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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
ERAP2
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "ERAP2" in MCE Product Catalog:
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1 Cited Publications
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ERAP2-IN-1 (compound 61) is an uncompetitive ERAP2 inhibitor. ERAP2-IN-1 specifically inhibits the ERAP2 peptide hydrolysis activity, inhibiting Arg-AMC hydrolysis with an IC50 of 27 μM and model peptide hydrolysis with an IC50 of 44 μM .
Cat. No.: HY-176778
CAS No.: 2790420-60-7
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BDM88951 (Compound 4 d) is a selective ERAP2 inhibitor with an IC50 of 19 nM. BDM88951 significantly inhibits antigen presentation. BDM88951 can be used for autoimmune diseases and cancers research .
Cat. No.: HY-139907B
Purity: 99.60%
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DG013A (formate) is a phosphinic acid tripeptide mimetic inhibitor. DG013A (formate) displays significantly weak affinity for both ERAP1 (IC50=33 nM) and ERAP2 (IC50=11 nM). DG013A (formate) can be used for the research of autoimmune disease and cancer .
Cat. No.: HY-RS04464
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ERAP2 Human Pre-designed siRNA Set A contains three designed siRNAs for ERAP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-139907
CAS No.: 2007955-07-7
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DG013A is a phosphinic acid tripeptide mimetic inhibitor. DG013A displays significantly weak affinity for both ERAP1 (IC50=33 nM) and ERAP2 (IC50=11 nM). DG013A can be used for the research of autoimmune disease and cancer .
Cat. No.: HY-139907A
CAS No.: 2758817-06-8
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DG013B is an epimer of DG013A (HY-139907). DG013B has weak affinity for ERAP1 and ERAP2 and is often used as a negative control to study the binding properties of DG013A and its analogues to ERAP1 and ERAP2 .
Cat. No.: HY-139907C
Purity: 99.57%
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DG013B formate is an epimer of DG013A (HY-139907). DG013B formate has weak affinity for ERAP1 and ERAP2 and is often used as a negative control to study the binding properties of DG013A and its analogues to ERAP1 and ERAP2 .
Cat. No.: HY-173022
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BDM_92499 is a nanomolar selective IRAP inhibitor, with an IC50 of 3.4 nM. BDM_92499 also inhibits ERAP1 and ERAP2, with IC50 values of 0.46 μM and 4.2 μM, respectively .
Cat. No.: HY-176778A
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(rac)-BDM88951 is the racemate of BDM88951 (HY-176778). BDM88951 (Compound 4 d) is a selective ERAP2 inhibitor with an IC50 of 19 nM. BDM88951 significantly inhibits antigen presentation in HEK cells. BDM88951 can be used for research on autoimmune diseases and cancer .
Cat. No.: HY-179625
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GSK235 is an orally active, selective and allosteric endoplasmic reticulum aminopeptidase 1 (ERAP1) inhibitor with pIC50 values of 8.45 and 7.59 for human and mouse ERAP1, respectively. GSK235 exhibits over 1000-fold selectivity for the two most homologous enzymes, ERAP2 and IRAP. GSK235 can regulate the immunopeptidome of cancer cells and enhance cancer cell antigenicity. GSK235 can be used for the study of colorectal cancer and arthritis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
