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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
ERN1
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "ERN1" in MCE Product Catalog:
1
1 Cited Publications
Target:
Research Areas:
IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM. IRE1α kinase-IN-1 displays 100-fold selectivity for IRE1α over the IRE1β isoform. IRE1α kinase-IN-1 inhibits ER stress-induced IRE1α oligomerization and autophosphorylation, and also inhibits IRE1α RNase activity (IC50=80 nM) [1].
1
Cat. No.: HY-174497
eGFP mRNA expresses green fluorescent protein derived from the jellyfish Aequorea victoria. eGFP is a commonly used direct-detection reporter gene in mammalian cell culture, which produces bright green fluorescence. This product is synthesized without modified nucleosides, with a Cap1 version cap analog at the 5' end and a 100nt PolyA tail at the 3' end. It can be used as a positive reference for IVT (in vitro transcription) or LNP delivery systems.
Cat. No.: HY-RS04507
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ERN1 Human Pre-designed siRNA Set A contains three designed siRNAs for ERN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS04508
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Ern1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ern1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS04509
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Research Areas:
Ern1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ern1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P73858
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: Serine/threonine-protein kinase/endoribonuclease IRE1; IRE1a; ERN1; IRE1
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Source:
Cat. No.: HY-P73256
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Serine/threonine-protein kinase/endoribonuclease IRE1; IRE1a; ERN1; IRE1
Species:
Source:
Cat. No.: HY-P80828A
Synonyms: ERN1; IRE1; Serine/threonine-protein kinase/endoribonuclease IRE1; Endoplasmic reticulum-to-nucleus signaling 1; Inositol-requiring protein 1; hIRE1p; Ire1-alpha; IRE1a
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
