4 Results for "

GPR173

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "GPR173" in MCE Product Catalog:

Cat. No.: HY-RS05683
Research Areas:  

Others

GPR173 Human Pre-designed siRNA Set A contains three designed siRNAs for GPR173 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS20162
Research Areas:  

Others

Gpr173 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gpr173 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS26666
Research Areas:  

Others

Gpr173 Rat Pre-designed siRNA Set A contains three designed siRNAs for Gpr173 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P5762A
Synonyms: PNX-14 TFA
Phoenixin-14 (PNX-14) TFA is an endogenous neuropeptide with multiple biological activities, and serves as the endogenous ligand of GPR173. Phoenixin-14 TFA reduces ROS production by inhibiting the HMGB1/TLR4/MyD88/NF-κB signaling axis, thereby exerting antioxidant and mitochondrial protective effects. Phoenixin-14 TFA inhibits FOXO3 phosphorylation by upregulating SIRT3 expression, suppresses apoptosis, and improves myocardial systolic/diastolic function. Phoenixin-14 TFA resists ferroptosis by activating the ATF4/SLC7A11/GPX4 axis; it activates ERK1/2 phosphorylation via GPR173. Phoenixin-14 TFA can be used in researches on neuroprotection, diabetes, cardiomyopathy, reproductive protection and so on .
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