Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
GSC cells
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "GSC cells" in MCE Product Catalog:
Target:
研究分野:
CP681301 is a potent CDK5 inhibitor. CP681301 shows antiproliferative activity. CP681301 decreases the expression of CD133, OLIG2, SOX2, KI67, pCDK5 protein level in GSCs (Glioma stem cells). CP681301 reduces self-renewal in mouse glioma xenografts. CP681301 shows anti-tumor activity in Drosophila .
Target:
研究分野:
2-Fluoropalmitic acid, an acyl-CoA synthetase inhibitor, acts as a candidate anti-glioma agent. 2-Fluoropalmitic acid suppresses the viability and stem-like phenotype of glioma stem cells (GSCs). 2-Fluoropalmitic acid also inhibits proliferation and invasion of glioma cell lines .
製品番号: HY-13768S1
CAS 番号: 1044904-10-0
製品番号: HY-174212
CAS 番号: 3037024-97-5
MXC-017 is a blood-brain barrier (BBB)-penetrant apoptosis inducer that directly targets Vimentin (VIM). MXC-017 prevents radiation-induced glioma stem cell (GSC) formation, while promoting G0/G1 cell cycle arrest and apoptosis. MXC-017 exhibits minimal off-target effects and shows no significant cytotoxicity. MXC-017 significantly prolongs median survival when used in combination with radiation therapy in glioblastoma (GBM) mouse models.
製品番号: HY-13768S
CAS 番号: 1133355-98-2
別名: SKF 104864A-d5; NSC 609669-d5
製品番号: HY-171172
CAS 番号: 2493080-16-1
Target:
GSC-718 is a CD22 inhibitor with an IC50 of 0.161 μM against mouse CD22. GSC-718 competitively blocks the binding of mouse CD22 to natural glycan ligands, and inhibits the interaction between CD22 and α2,6-sialylated ligands. GSC-718 promotes B cell proliferation and enhances antibody production. GSC-718 can be used in the research of B cell lymphoma and rheumatoid arthritis .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
