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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
HADA
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "HADA" in MCE Product Catalog:
14
14 Cited Publications
Synonyms: HCC-Amino-D-alanine hydrochloride
Cat. No.: HY-DY1044
CAS No.: 2253733-10-5
Solvent and concentration: DMSO: 50 mM
Cat. No.: HY-W014692
CAS No.: 76387-70-7
Synonyms: N-t-Boc-amino-D-alanine; Boc-D-Dap-OH
Target:
Research Areas:
Boc-D-2,3-diaminopropionic acid (N-t-Boc-amino-D-alanine; Boc-D-Dap-OH) is a Boc-protected D-diamino acid building block that serves as a precursor for the synthesis of fluorescent carbon dots and fluorescent D-amino acid probes (such as HADA and NADA), and can be used in amide coupling reactions. Boc-D-2,3-diaminopropionic acid is applicable to fluorescent probe development and chemical biology research .
Cat. No.: HY-187335
Target:
Research Areas:
HadAB/InhA=IN-1 is a dual inhibitor of Mycobacterium tuberculosis InhA and HadAB with an InhA IC50 of 0.81 μM. HadAB/InhA=IN-1 inhibits InhA enzymatic activity in the FAS-II pathway of mycolic acid biosynthesis. HadAB/InhA=IN-1 undergoes EthA-mediated activation to covalently bind HadA and inhibit HadAB dehydratase function in the same FAS-II pathway. HadAB/InhA=IN-1 reduces mycolic acid-containing lipid and mycolic acid production, and accumulates standard fatty acids in Mycobacterium tuberculosis. HadAB/InhA=IN-1 exhibits antimycobacterial activity against drug-susceptible, ethA-deficient, and multi-drug-resistant Mycobacterium tuberculosis isolates. HadAB/InhA=IN-1 shows cytotoxic effects against human cancer and immortalized normal lung fibroblast cells. HadAB/InhA=IN-1 can be used for the research of tuberculosis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
