9 Results for "

HGS

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "HGS" in MCE Product Catalog:

Cat. No.: HY-P99299
CAS No.: 845816-02-6
Synonyms: HGS-ETR 2; ETR2-ST01

Target:  

Apoptosis

Research Areas:  

Cancer

Lexatumumab (HGS-ETR 2) is a human agonistic TRAIL receptor 2 (TRAIL-R2, DR5, APO-2) IgG4κ type monoclonal antibody. Lexatumumab induces apoptosis in malignant mesothelioma. Lexatumumab can be used for malignant pleural mesothelioma (MPM) research .
loading...
    loading...
Cat. No.: HY-P99265
CAS No.: 658052-09-6
Synonyms: HGS-ETR1; Anti-Human TNFRSF10A Recombinant Antibody

Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

Mapatumumab (HGS-ETR1) is a fully human IgG1 agonistic monoclonal antibody that targets tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1). Mapatumumab can be used for the research of cancer .
loading...
    loading...
Cat. No.: HY-P990592
Synonyms: E-6071; HGS-1035

Target:  

CCR

Research Areas:  

Inflammation/Immunology

GSK-3050002 (E-6071) is a CHO-expressed humanized antibody that targets CCL20. GSK-3050002 (E-6071) features a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for GSK-3050002 (E-6071) can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
loading...
    loading...
Cat. No.: HY-120434
CAS No.: 949963-04-6
Synonyms: HGS1029
Target:  

IAP

Research Areas:  

Cancer

AEG40826 (HGS1029), a second mitochondria-derived activator of caspases (SMAC) mimetic, is an inhibitor of apoptosis (IAP) inhibitor. AEG40826 degrades cellular IAP1 (cIAP1) and blocks TNF-α pro-survival signaling. AEG40826 can be used for cancer research .
loading...
    loading...
Cat. No.: HY-P991541

Target:  

CCR HIV

Research Areas:  

Infection

HGS101 is a fully human CCR5 monoclonal antibody with high affinity to CCR5. HGS101 binds to the 2nd extracellular loop (ECL-2) and acts as a signal antagonist. HGS101 restores Maraviroc (HY-13004) inhibition of Maraviroc-resistant HIV-1 infection of PBMCs. HGS101 shows anti-HIV activity by inhibiting CCR5 signaling in simian immunodeficiency virus-uninfected RMs models .
loading...
    loading...
Cat. No.: HY-P991653

Target:  

CCR HIV

Research Areas:  

Infection

HGS004 is a humanized IgG4 monoclonal antibody inhibitor targeting CCR5. HGS004 has potent antivival activity against a diverse panel of CCR5-tropic HIV-1 and durg (such as Maraviroc (HY-13004))-resistant strains. HGS004 can be used for HIV-1 infections research .
loading...
    loading...
Cat. No.: HY-RS06155
Research Areas:  

Others

HGS Human Pre-designed siRNA Set A contains three designed siRNAs for HGS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-P88079
Synonyms: HRS

Host:  

Mouse

Application:  

ICC/IF

Reactivity:  

Human, Mouse, Rat

loading...
    loading...
Cat. No.: HY-P88079A
Synonyms: HRS

Host:  

Mouse

Application:  

ICC/IF

Reactivity:  

Human, Mouse, Rat

loading...
    loading...