AEG40826
AEG40826 (HGS1029), a second mitochondria-derived activator of caspases (SMAC) mimetic, is an inhibitor of apoptosis (IAP) inhibitor. AEG40826 degrades cellular IAP1 (cIAP1) and blocks TNF-α pro-survival signaling. AEG40826 can be used for cancer research.
For research use only. We do not sell to patients.
- CAS No.: 949963-04-6
- Formula: C58H80N10O8
- Molecular Weight:1045.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 949963-04-6
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Molecular Weight 1045.32
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Formula C58H80N10O8
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SMILES
CN[C@@H](C)C(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@@H](C1)NC(C2=CC=C(C=C2)C(N[C@@H]3CN([C@@H](C3)C(N[C@H]4C5=CC=CC=C5CCC4)=O)C([C@H](C(C)(C)C)NC([C@H](C)NC)=O)=O)=O)=O)C(N[C@H]6C7=CC=CC=C7CCC6)=O)=O)=O
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Synonyms
HGS1029
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AEG40826 Related Classifications
HY-120434 Related Classifications
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