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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
HLB
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "HLB" in MCE Product Catalog:
Cat. No.: HY-168439
CAS No.: 2566733-45-5
Target:
Research Areas:
HLB-0532259 is a Aurora-A/N-Myc PROTAC degrader, with a DC50 of 20.2 nM against Aurora-A in MCF-7 cells; its DC50 values against N-Myc are 179 nM in SK-N-BE (2) cells and 229 nM in Kelly cells, respectively. HLB-0532259 induces apoptosis (apoptosis) in MYCN-amplified neuroblastoma cells and inhibits tumor growth in mouse xenograft models. HLB-0532259 can be used for the research of neuroblastoma .
Cat. No.: HY-W007791
CAS No.: 5399-87-1
Synonyms: 6-Chloropurine riboside
Research Areas:
Chloropurine (6-Chloropurine) riboside is an analog of Adenosine (HY-B0228). Chloropurine riboside acts as a chemical modifier for affinity labeling of RNase A. Chloropurine riboside exhibits antibacterial activity and can be used in studies related to citrus Huanglongbing (HLB) .
Cat. No.: HY-168440
CAS No.: 2541626-73-5
Research Areas:
Aurora-A ligand 1 is a high-affinity and specific Aurora-A inhibitor with a dissociation constant (Kd) value of 0.85 nM. Aurora-A ligand 1 can serve as a ligand for target protein (Ligands for Target Protein for PROTAC) for the development of PROTAC Aurora-A degraders with antitumor activity. Aurora-A ligand 1 can be used for the synthesis of HLB-0532259 (HY-168439). HLB-0532259 shows anti-tumor activity against neuroblastoma .
4-(2,4,4-Trimethylpentan-2-yl)benzene-PEG4-OH, a nonionic surfactant with a low hydrophile-lypophile balance (HLB) value and dispersible in aqueous solution at room temperature, has a Krafft point above the room temperature. 4-(2,4,4-Trimethylpentan-2-yl)benzene-PEG4-OH has the potential for the research of the hepatitis C virus (HCV) .
Cat. No.: HY-105035
CAS No.: 96497-67-5
Synonyms: Cytorhodin S; HLB 817
Target:
Research Areas:
Rodorubicin (Cytorhodin S) is a tetraglycosidic anthracycline with preclinical antitumor activity .
Cat. No.: HY-183873
CAS No.: 2850362-12-6
Target:
Research Areas:
HLB-0532247 is a cell-permeable phosphoramidate prodrug of 3'-deoxy-3',4'-didehydrocytidine (ddhC). HLB-0532247 increases the intracellular level of the endogenous antiviral nucleotide ddhCTP (HY-128788). HLB-0532247 reduces the titers of Zika virus and West Nile virus in cell cultures. HLB-0532247 can be used in studies related to Zika virus infection, West Nile virus infection, and coronavirus infection .
Cat. No.: HY-P700228AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFSF1B; Lymphotoxin-alpha (LT-α); LTalpha; Ltx; TNF-be; TNFSF1; Tnf; Tnfb; Tnfsf; Tnfsf1b; Tnlg1e; HLB38; HLB382; lymph
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
