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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
HSP72
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "HSP72" in MCE Product Catalog:
5
5 Cited Publications
CCT251236 is an orally available pirin ligand from a heat shock transcription factor 1 (hsf1) phenotypic screen with an IC50 of 19 nM for inhibition of HSF1-mediated HSP72 induction.
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CCT018159 is an ATP-competitive HSP90β inhibitor, with an IC50 of 3.2 μM against human HSP90β ATPase and 6.6 μM against yeast HSP90β ATPase. CCT018159 induces cell cycle arrest and apoptosis in tumor cells, and inhibits invasion and angiogenesis. CCT018159 is applicable to cancer-related research .
Cat. No.: HY-P11052
CAS No.: 1140483-17-5
Cat. No.: HY-RS06424
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HSPA1A Human Pre-designed siRNA Set A contains three designed siRNAs for HSPA1A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-185764
CAS No.: 2614310-11-9
TCI 18 is a ligand of HSP72 with a Ki value of 4.7 μM. TCI 18 forms a covalent bond with Lys56 residue of HSP72 via a process involving initial reversible binding, conversion to a pre-covalent complex, and subsequent covalent bond formation. TCI 18 addresses the undruggable target HSP72 .
Cat. No.: HY-123303
CAS No.: 75041-32-6
Synonyms: NZ-28
NSC-134754 (NZ-28) is a dehydroemetine derivative and heat shock protein (HSP) induction inhibitor. NSC-134754 acts at the post-transcriptional level, targets Hsp72 and Hsp27, and does not alter general protein synthesis, HSF-1 transcriptional activity, or Hsp mRNA levels. NSC-134754 can be used for the research of multiple myeloma, prostate carcinoma, colon carcinoma .
Cat. No.: HY-P701004
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HSP70-1; HSPA1A; HSP72 ; HSPA1; HSX70
Cat. No.: HY-101026R
CAS No.: 1693731-40-6
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CCT251236 (Standard) is the analytical standard of CCT251236 (HY-101026). This product is intended for research and analytical applications. CCT251236 is an orally available pirin ligand from a heat shock transcription factor 1 (hsf1) phenotypic screen with an IC50 of 19 nM for inhibition of HSF1-mediated HSP72 induction.
Cat. No.: HY-P73105
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Heat shock 70 kDa protein 1B; HSP70-2; HSPA1B; HSP72
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Cat. No.: HY-RS18094
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Hspa1a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Hspa1a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS06425
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HSPA1B Human Pre-designed siRNA Set A contains three designed siRNAs for HSPA1B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P85508
Synonyms: DAQB 147D11.1 001; FLJ54303; FLJ54370; FLJ54392; FLJ54408; FLJ75127; Heat shock 70 kDa protein 1; Heat shock 70 kDa protein 1/2; Heat shock 70 kDa protein 1A/1B; heat shock 70kDa protein 1A; Heat shock 70kDa protein 1B; Heat shock induced protein; heat shock protein 70; HSP70 1; HSP70 2; HSP70-1/HSP70-2; HSP70-1A; HSP70.1; HSP70.1/HSP70.2; HSP70I; HSP71_HUMAN; HSP72; HSPA1; HSPA1A; HSPA1B; XXbac BCX40G17.3 001.
Cat. No.: HY-RS24569
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Hspa1a Rat Pre-designed siRNA Set A contains three designed siRNAs for Hspa1a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25750
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Hspa1b Rat Pre-designed siRNA Set A contains three designed siRNAs for Hspa1b gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-117252
CAS No.: 1118861-60-1
HS-72 is a selective allosteric inducible heat shock protein 70 Hsp70i inhibitor. HS-72 reduces ATP affinity of Hsp70i, elevates caspase 3/7 apoptotic activity, and promotes degradation of Hsp70 client proteins, including HER2 and Akt, and blocks DENV entry by disrupting Hsp70i association with the DENV receptor complex. HS-72 can be used for breast cancer and dengue virus infection research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
