4 Results for "

HT-29 (colon adenocarcinoma)

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "HT-29 (colon adenocarcinoma)" in MCE Product Catalog:

Cat. No.: HY-N8491
CAS No.: 38049-26-2
Dihydrocarveol is an anticancer agent. Dihydrocarveol shows inhibitory activity against human colon adenocarcinoma cells (HCT-116, HT-29, COLO320DM) with an IC50 value of 28.31 μM in HCT-116 cells. Dihydrocarveol is promising for research of colon cancer .
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Cat. No.: HY-155152
CAS No.: 3052839-42-3
Target:  

P-glycoprotein BCRP

Research Areas:  

Cancer

P-gp/BCRP-IN-2 (compound 15) is an oxadiazole derivative and a dual inhibitor of the ABC transporter P-glycoprotein (IC50: 1.6 nM) and BCRP (IC50: 600 nM). P-gp/BCRP-IN-2 also enhances the anti-proliferative effects of Doxorubicin (HY-15142A) in drug-resistant human adenocarcinoma colon cancer cell lines HT29/DX and MDCK-MDR1 cells .
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Cat. No.: HY-170966
Target:  

HDAC

Research Areas:  

Cancer

HDAC1-IN-9 (13c) is a HDAC1 inhibitor. HDAC1-IN-9 inhibits HDAC1 enzyme with an IC50 of 1.07 µM. HDAC1-IN-9 exhibits the highest anti-proliferative effect against HT-29 (human colon adenocarcinoma), with anIC50 of 1.78 μM. HDAC1-IN-9 induces substantial Apoptosis in HCT-116 (human colon cancer) cells. HDAC1-IN-9 possesses antiangiogenic property. HDAC1-IN-9 reduces the expression levels of VEGFR-2 and phosphorylated VEGFR-2 (pVEGFR-2) by approximately 80 % .
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Cat. No.: HY-N17610
CAS No.: 53596-71-7
2',4'-Dihydroxydihydrochalcone exhibits cytotoxic activity against HT-29 colon adenocarcinoma cells (IC50 = 1.8 μM). 2',4'-Dihydroxydihydrochalcone may be used in research on cancers such as colon adenocarcinoma .
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