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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
37 Results for "
HaloTag protein
" in MedChemExpress (MCE) Product Catalog:
Products (37)
37 Results for "HaloTag protein" in MCE Product Catalog:
2
2 Cited Publications
Target:
Research Areas:
HaXS8 is a dimerizer that can promote a covalent and irreversible intracellular dimerization of HaloTag and SNAP-tagged proteins of interest. HaXS8 does not interfere with PI3K/mTOR signaling .
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Synonyms: JF646, SE; JF646, NHS
Cat. No.: HY-131027
Purity: 99.87%
Synonyms: JF646, Azide
Cat. No.: HY-131028
Purity: ≥95.0%
Synonyms: JF646 TFA
Cat. No.: HY-131029
Purity: ≥95.0%
Synonyms: JF646, Maleimide
Cat. No.: HY-151071
CAS No.: 2488761-18-6
Research Areas:
TMX-3013 is a CDK inhibitor capable of inhibiting the activity of CDK1, CDK2, CDK4, CDK5, and CDK6, with IC50 values of 0.9 nM, <0.5 nM, 24.5 nM, 0.5 nM, and 15.6 nM, respectively. TMX-3013 can be used as a target protein ligand, conjugated with the PROTAC linker and the CRBN ligand Thalidomide (HY-14658) for the synthesis of PROTAC TMX-2138 (HY-164906). TMX-3013 can also act as an effector ligand, binding to target proteins HaloTag or FKBP, and can be used in the synthesis of regulated induced proximity targeting chimeras (RIPTACs) .
Cat. No.: HY-W008425
CAS No.: 10160-24-4
Synonyms: 7-Bromoheptan-1-ol
Research Areas:
7-Bromo-1-heptanol (7-Bromoheptan-1-ol) acts as a HaloTag-GPSM2 inhibitor and an organic synthesis intermediate. It forms a covalent irreversible bond with HaloTag-GPSM2, thereby blocking the subsequent labeling effect of fluorescent HaloTag ligands and enabling pulse-chase analysis of protein turnover. 7-Bromo-1-heptanol can be used to synthesize PROTAC BET degraders and multivalent glycoporphyrin antiviral compounds. It is applicable to cancer-related research .
Cat. No.: HY-131026
Synonyms: JF635, SE; JF635, NHS
Synonyms: JF646, Tetrazine
Cat. No.: HY-131030
CAS No.: 2127150-20-1
Synonyms: JF669, SE; JF669, NHS
Cat. No.: HY-130736
CAS No.: 1811539-32-8
Synonyms: JF549, SE; JF549, NHS
Synonyms: JF525, SE; JF525, NHS
Synonyms: JF549 TFA
Target:
Research Areas:
VL285 Phenol is a phenol-based VL285 analog. VL285 is an E3 ubiquitin ligase VHL ligand and can be used in the synthesis of HaloPROTAC3, degrading HaloTag7 fusion protein (IC50=0.34 μM).
Cat. No.: HY-160902
CAS No.: 2241668-58-4
2G-HaloAUTAC (Compound tt44) is a Autophagy-targeting chimera (2G-HaloAUTAC) that improves the activity of AUTACs by replacing the L-Cysteine (L-Cys) linker with other structures. 2G-HaloAUTAC exhibits degradation activity against EGFP-HaloTag protein through an Autophagic mechanism .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
