29 Results for "

HeLa S3

" in MedChemExpress (MCE) Product Catalog:
Products (29)

29 Results for "HeLa S3" in MCE Product Catalog:

33
33 Publications Verification
Cat. No.: HY-B0350A
CAS No.: 156-54-7
Synonyms: Butanoic acid sodium; Butyric acid sodium
Target:  

HDAC

Sodium butyrate ((Butanoic acid; Butyric acid) sodium) is an orally active HDAC inhibitor. Sodium butyrate induces hyperacetylation of core histones and affects phosphorylation of H1/H2A, thereby altering chromatin structure and regulating gene expression. Sodium butyrate can be used in research related to various cancers, inflammatory bowel disease, and sickle cell anemia .
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3
3 Cited Publications
Cat. No.: HY-13057
CAS No.: 382607-78-5
Purity:  ≥95.0%
Synonyms: Glucose-conjugated MGMT inhibitor
Target:  

DNA Methyltransferase

Research Areas:  

Cancer

O6BTG-octylglucoside is a potent O 6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells.
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1
1 Cited Publications
Cat. No.: HY-113474
CAS No.: 775-01-9
Purity:  98.56%
3,4‑Dihydroxymandelic acid is a metabolite of Norepinephrine (HY-13715) with free radical scavenging and antioxidant activities. 3,4-Dihydroxymandelic acid acts as a chemoattractant for enterohaemorrhagic Escherichia coli (EHEC), regulates virulence gene expression and bacterial adhesion to intestinal epithelial cells in a QseC-dependent manner, and targets EHEC to preferred infection sites. 3,4‑Dihydroxymandelic acid can be used in studies related to oxidative stress and enterohaemorrhagic Escherichia coli infection .
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1
1 Cited Publications
Cat. No.: HY-136248
CAS No.: 174961-75-2
Purity:  96.15%
Synonyms: Tyramide-Cy3
Cyanine 3 Tyramide (Tyramide-Cy3) is an orange fluorescent dye used as a reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition, which serves as a signal amplification technique in immunoassays and in situ nucleic acid hybridization .
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Cat. No.: HY-23430
CAS No.: 7365-44-8
TES is an excellent hydrogen ion buffer. TES has characteristics such as an appropriate dissociation constant, a low metal-binding constant, and high water solubility. TES can be used in the research of mammalian cell culture, viruses, and so on .
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Cat. No.: HY-141466
CAS No.: 992-67-6
Crotonyl-CoA, a high-energy acyl donor, is an intermediate in the fermentation of butyric acid, and in the metabolism of lysine and tryptophan. Crotonyl-CoA is important in the metabolism of fatty acids and amino acids. Crotonyl-CoA acts as a substrate for p300’s histone crotonyltransferase activity, competing with acetyl-CoA for p300-mediated histone acylation reactions. Crotonyl-CoA regulates global and gene-specific histone crotonylation levels in cells, with cellular concentration changes altering histone crotonylation at regulatory elements of activated genes. Crotonyl-CoA serves as the substrate for crotonyl-CoA reductase/carboxylase (CCRC)-catalyzed NADPH-mediated reduction and carbon dioxide trapping to form unusual alkylmalonyl-CoA polyketide synthase extender units. Crotonyl-CoA can be used for the research of LPS-induced inflammatory response .
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Cat. No.: HY-108262
CAS No.: 121569-61-7
Synonyms: 7-epi-Hydroxystaurosporine
UCN-02 (7-epi-Hydroxystaurosporine) is a selective protein kinase C (PKC) inhibitor with a PKC IC50 value of 62 nM and a PKA IC50 value of 0.25 μM. UCN-02 can be produced by Streptomyces strain N-126. UCN-02 can be used for the research of breast carcinoma .
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Cat. No.: HY-101775A
CAS No.: 52238-35-4
Purity:  ≥99.0%
Target:  

Topoisomerase

Research Areas:  

Cardiovascular Disease Cancer

9-Hydroxyellipticine hydrochloride is a inhibitor of Topo II and RyR. 9-Hydroxyellipticine hydrochloride exhibits antitumor, antioxidant and catecholamine-releasing activities. 9-Hydroxyellipticine hydrochloride exhibits IC50 values of 1.6 μM and 1.2μM in Hela S-3 and 293T cells, respectively .
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Cat. No.: HY-N9172
CAS No.: 476630-49-6
Eupaglehnin C is a germacrane-type sesquiterpenoi. Eupaglehnin C can be isolated from the MeOH extract of Eupatorium glehni (Compositae). Eupaglehnin C has cytotoxic activity against HeLa-S3 cancer cell lines .
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Cat. No.: HY-142124
CAS No.: 174513-95-2
Kalimantacin A is an Antibiotic. Kalimantacin A is produced by Alcaligenes sp. YL-02632S. Kalimantacin A inhibits bacterial fatty acid biosynthesis. Kalimantacin A exerts selective antibacterial activity against staphylococci, including multidrug-resistant Staphylococcus aureus and Staphylococcus epidermidis. Kalimantacin A shows no activity against most Gram-negative bacteria and fungi. Kalimantacin A exhibits anticancer activity against leukemia and cervical cancer. Kalimantacin A can be used in studies related to staphylococcal infections .
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Cat. No.: HY-N13976
CAS No.: 189871-55-4
Target:  

Others

Belactosin C is found in the strain of Streptomyces sp. that inhibits HeLa S3 cells with the IC50 of 200 μM .
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Cat. No.: HY-N10542
CAS No.: 151923-86-3
Aplyronine C is an active compound. Aplyronine C shows potent antitumor activity and has cytotoxicity against HeLa-S3 cells with an IC50 values of 22 nM. Aplyronine C can be used for the research of cancer .
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Cat. No.: HY-N10541
CAS No.: 151923-85-2
Aplyronine B is an active compound. Aplyronine B shows potent antitumor activity and has cytotoxicity against HeLa-S3 cells with an IC50 values of 2.9 nM. Aplyronine B can be used for the research of cancer .
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Cat. No.: HY-N8512
CAS No.: 129277-10-7
Asperfuran is an antifungal dihydrobenzofuran derivative produced by a strain of Aspergillus oryzae. Asperfuran weakly inhibits chitin synthase from Coprinus cinereus. Asperfuran shows weak cytotoxicity In HeLa S3 and L1210 cells with an IC50 of 25 μg/ml .
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Cat. No.: HY-N5186
CAS No.: 154277-21-1
Cypemycin is a linaridin antibiotic that can inhibit cancer cell activity, inhibits P388 leukemia cells with IC50 of 1.3 μg/mL. Cypemycin can inhibit human tumor cells such as HeLa S3, HHCC-1, HCCS-M and Slex with IC50 of >25 μg/mL .
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Cat. No.: HY-101775
CAS No.: 51131-85-2
Target:  

Topoisomerase

Research Areas:  

Cardiovascular Disease Cancer

9-hydroxyellipticine is an inhibitor of Topo II and RyR, exhibiting high affinity for DNA with a Pka value of 9.8 at pH 7.4. It has antitumor, antioxidant, and catecholamine-releasing activities, with IC50 values of 1.6 μM and 1.2 μM for Hela S-3 and 293T cells, respectively. It also demonstrates anticancer effects in L1210 leukemia mice .
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Cat. No.: HY-101775AR
CAS No.: 52238-35-4
9-Hydroxyellipticine (hydrochloride) (Standard) is the analytical standard of 9-Hydroxyellipticine (hydrochloride). This product is intended for research and analytical applications. 9-Hydroxyellipticine hydrochloride is a inhibitor of Topo II and RyR. 9-Hydroxyellipticine hydrochloride exhibits antitumor, antioxidant and catecholamine-releasing activities. 9-Hydroxyellipticine hydrochloride exhibits IC50 values of 1.6 μM and 1.2μM in Hela S-3 and 293T cells, respectively .
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Cat. No.: HY-P10596
CAS No.: 1242413-05-3
Target:  

Bacterial Fungal

Research Areas:  

Infection Cancer

Lasioglossin-III is an antimicrobial peptide that can be isolated from the venom of wild bees. Lasioglossin-III has high antibacterial activity against Gram-positive and Gram-negative bacteria, antifungal activity and antitumor activity. Lasioglossin-III has certain cytotoxicity against three cancer cell lines (HeLa S3, CRC SW 480 and CCRF-CEM T) with IC50 values ​​of 4, 18 and 5 μM, respectively .
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Cat. No.: HY-N13975
CAS No.: 189871-53-2
Target:  

Others

Belactosin A is found in the strain of Streptomyces sp. that inhibits HeLa S3 cells with the IC50 of 51 μM .
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Cat. No.: HY-N14438
CAS No.: 125108-66-9
Furaquinocin A can kill HeLa S3 and B16 melanoma cells, but has no antibacterial activity .
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