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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
Hydroxy bosentan
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "Hydroxy bosentan" in MCE Product Catalog:
Cat. No.: HY-121385
CAS No.: 253688-60-7
Synonyms: Ro 48-5033
Target:
Cat. No.: HY-121385S
CAS No.: 1246817-57-1
Synonyms: Ro 48-5033-d6
Cat. No.: HY-135390
CAS No.: 253688-62-9
Synonyms: Ro 64-1056
Target:
Research Areas:
Hydroxy desmethyl Bosentan (Ro 64-105) is a Bosentan metabolism produced by the cytochrome P450 enzymes CYP2C9 and CYP3A4 in the liver . Bosentan is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively. Bosentan can be used in treatment of pulmonary arterial hypertension .
Cat. No.: HY-121385S1
CAS No.: 1065472-91-4
Synonyms: Ro 48-5033-d4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
