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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
IBAT
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "IBAT" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: A 3309; AZD 7806
Research Areas:
Elobixibat (A 3309; AZD 7806) is an orally active, bile acid transporter (IBAT) inhibitor with IC50 values ??of 0.53 nM (human IBAT), 0.13 nM (mouse IBAT), and 5.8 nM (canine IBAT). Elobixibat can lower LDL cholesterol, increase serum GLP-1, promote colonic motility, and has the potential to study metabolic syndrome. Elobixibat can be used in the study of chronic functional constipation (CIC), dyslipidemia, non-alcoholic hepatitis, and liver tumors in the elderly .
1
1 Cited Publications
Synonyms: A 3309 hydrate; AZD 7806 hydrate
Research Areas:
Elobixibat (A 3309; AZD 7806) hydrate is an orally active, bile acid transporter (IBAT) inhibitor with IC50 values ??of 0.53 nM (human IBAT), 0.13 nM (mouse IBAT), and 5.8 nM (canine IBAT). Elobixibat hydrate can lower LDL cholesterol, increase serum GLP-1, promote colonic motility, and has the potential to study metabolic syndrome. Elobixibat hydrate can be used in the study of chronic functional constipation (CIC), dyslipidemia, non-alcoholic hepatitis, and liver tumors in the elderly .
Cat. No.: HY-16747
CAS No.: 228113-66-4
Synonyms: SHP625 chloride; LUM001 chloride; LopixIBAT chloride
Research Areas:
Maralixibat (SHP625) chloride is an orally active ileal bile acid transporter (IBAT) inhibitor. Maralixibat chloride can be used for the research of rare cholestatic liver diseases including Alagille syndrome (ALGS), progressive familial intrahepatic cholestasis (PFIC) and biliary atresia .
Cat. No.: HY-148795
CAS No.: 2460667-52-9
Research Areas:
Ritivixibat is an apical sodium-dependent bile acid transporter (ASBT/IBAT) inhibitor. Ritivixibat blocks ASBT/IBAT function, thereby reducing bile acid reabsorption, regulating bile acid homeostasis and alleviating liver injury. Ritivixibat protects cholangiocytes from damage caused by cytotoxic bile acids. Ritivixibat is applicable to research related to primary sclerosing cholangitis .
Cat. No.: HY-19264
CAS No.: 178961-24-5
Research Areas:
264W94 is a potent ileal bile acid transporter (IBAT) inhibitor and a new cholesterol lowering agent. 264W94 has CYP7A1 induction, and antilipemic action .
Cat. No.: HY-15790H
CAS No.: 439087-68-0
Synonyms: (S)-A 3309; (S)-AZD 7806
Research Areas:
(S)-Elobixibat is the S enantiomer of Elobixibat (HY-15790). (S)-Elobixibat is an orally effective Apical Sodium-Dependent Bile (IBAT) inhibitor. (S)-Elobixibat decreases LDL cholesterol, increases serum GLP-1, promotes colon motility, and has the potential to study metabolic syndrome. (S)-Elobixibat can be used to study constipation, dyslipidemia, non-alcoholic hepatitis, and liver tumors .
Cat. No.: HY-15790S
Synonyms: A 3309-d5; AZD 7806-d5
Cat. No.: HY-15790R
CAS No.: 439087-18-0
Synonyms: A 3309 (Standard); AZD 7806 (Standard)
Research Areas:
Elobixibat (Standard) is the analytical standard of Elobixibat (HY-15790). This product is intended for research and analytical applications. Elobixibat (A 3309; AZD 7806) is orally active, bile acid transporter (IBAT) inhibitor with IC50 values ??of 0.53 nM (human IBAT), 0.13 nM (mouse IBAT), and 5.8 nM (canine IBAT). Elobixibat can lower LDL cholesterol, increase serum GLP-1, promote colonic motility, and has the potential to treat metabolic syndrome. Elobixibat can be used in the study of chronic functional constipation (CIC), dyslipidemia, non-alcoholic hepatitis, and liver tumors in the elderly .
Cat. No.: HY-19298
CAS No.: 151165-96-7
Research Areas:
S-8921 is an ileal Na +/bile acid cotransporter (IBAT) inhibitor.
Cat. No.: HY-RS12987
Target:
Research Areas:
Slc10a2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc10a2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS12988
Target:
Research Areas:
Slc10a2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Slc10a2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS12986
Target:
Research Areas:
SLC10A2 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC10A2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P705614
Purity: Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: Apical sodium-dependent bile acid transporter; ASBT; Ileal sodium-dependent bile acid transporter; IBAT; ISBT; Na+; Sodium/taurocholate cotransporting polypeptide, ileal; Solute carrier family 10 member 2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
