10 Results for "

IL-1RI

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "IL-1RI" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P99171
CAS No.: 1129435-60-4

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Gevokizumab is a potent anti-IL-1β antibody, negatively modulates IL-1β signaling through an allosteric mechanism. Gevokizumab selectively decreases the binding affinity of IL-1β for the IL-1 receptor type I (IL-1RI) signaling receptor instead of IL-1 counter-regulatory decoy receptor (IL-1 receptor type II) [1] .
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1
1 Cited Publications
Cat. No.: HY-108810
CAS No.: 914613-48-2
Purity:  99.64%
Synonyms: ILaris; ACZ 885
Canakinumab (ACZ885) is a recombinant human anti-IL-1β monoclonal antibody. Canakinumab shows IC50 values of 43.6 and 40.8 pM for human and marmoset IL-1β, respectively. The mode of action of canakinumab is based on the neutralization of IL-1β signaling, resulting in suppression of inflammation related to disorders of autoimmune origin [1] .
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Cat. No.: HY-P70286
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rMuInterleukin-1 receptor type 1/IL-1R1, His ; Interleukin-1 receptor type 1; IL-1R-1; IL-1RT1; IL-1 RI; CD121a
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Cat. No.: HY-P74822
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-1 receptor type 1; IL-1R-1; CD121a; IL1R1; IL1R; IL1RA; IL1RT1
Species:  
Rat
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Cat. No.: HY-P76995
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-1 receptor type 1; IL-1R-1; CD121a; IL1R1; IL1R; IL1RA; IL1RT1
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Cat. No.: HY-P76996
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-1 receptor type 1; IL-1R-1; CD121a; IL1R1; IL1R; IL1RA; IL1RT1
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Cat. No.: HY-P74821
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-1 receptor type 1; IL-1R-1; CD121a; IL1R1; IL1R; IL1RA; IL1RT1
Species:  
Rat
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Cat. No.: HY-P72569
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-1 receptor type 1; IL-1R-1; IL-1RT-1; Interleukin-1 receptor alpha; IL-1R-alpha; p80; CD121a    
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Cat. No.: HY-P74823
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-1 receptor type 1; IL-1R-1; CD121a; IL1R1; IL1R; IL1RA; IL1RT1
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Cat. No.: HY-P73185
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-1 receptor type 1; IL-1R-1; CD121a; IL1R1; IL1R; IL1RA; IL1RT1
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