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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
INCENP
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "INCENP" in MCE Product Catalog:
Research Areas:
SK-3-91 is a multi-kinase PROTAC degrader that induces the degradation of the maximum number of unique kinases (over 125 distinct kinases) simultaneously. SK-3-91 induces protein degradation via the ubiquitin biotinylation (E-STUB) pathway, such as inducing the degradation of YTHDF2. SK-3-91 also inhibits cell proliferation and induces cell morphological changes. SK-3-91 can be used in research related to acute lymphoblastic leukemia, multiple myeloma, neuroblastoma, ovarian cancer, mantle cell lymphoma, and gastric cancer .
Cat. No.: HY-RS06805
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INCENP Human Pre-designed siRNA Set A contains three designed siRNAs for INCENP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS21874
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Incenp Mouse Pre-designed siRNA Set A contains three designed siRNAs for Incenp gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-116190
CAS No.: 1430741-35-7
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CFI-401870 is an orally active threonine tyrosine kinase (TTK (Mps1)) inhibitor with an IC50 of 3.1 nM. CFI-401870 exhibits IC50s against PLK4, KDR, AURKA and other kinases such as AURKB/INCENP were all greater than 1 μM.CFI-401870 inhibits the growth of various cancer cells, causing chromosome lag, an increase in aneuploidy and cell cycle arrest. CFI-401870 can be used for the study of cancers such as colon cancer .
Cat. No.: HY-P702967
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Inner centromere protein; INCENP
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Cat. No.: HY-RS28391
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Incenp Rat Pre-designed siRNA Set A contains three designed siRNAs for Incenp gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-184329
CAS No.: 3114874-73-3
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PROTAC AURKB Degrader-1 is a selective AURKB PROTAC degrader with a DC50 value of 0.6 nM. PROTAC AURKB Degrader-1 promotes ubiquitination and degradation of AURKB. PROTAC AURKB Degrader-1 downregulates the expression levels of chromosomal passenger complex components Borealin, INCENP, Survivin as well as the transcription factor YY1. PROTAC AURKB Degrader-1 induces G2/M phase arrest and triggers Apoptosis in cells. PROTAC AURKB Degrader-1 serves as a chemical probe for biological studies of the chromosomal passenger complex. PROTAC AURKB Degrader-1 can be used in research related to acute myeloid leukemia, colorectal cancer, and non-small cell lung cancer .
Cat. No.: HY-P87277
Synonyms: binds and activates aurora B and C in vivo and in vitro antibody; Chromosomal passenger protein antibody; INCE_HUMAN antibody; INCENP antibody; Inner centromere protein antibody; Inner centromere protein antigens 135/155kDa antibody; Inner centromere protein antigens 135kD 155kD antibody; Inner centromere protein INCENP antibody
Cat. No.: HY-P87277A
Synonyms: binds and activates aurora B and C in vivo and in vitro antibody; Chromosomal passenger protein antibody; INCE_HUMAN antibody; INCENP antibody; Inner centromere protein antibody; Inner centromere protein antigens 135/155kDa antibody; Inner centromere protein antigens 135kD 155kD antibody; Inner centromere protein INCENP antibody
Cat. No.: HY-P705736
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: AURC-INCENP complex; Aurora kinase C; Serine/threonine-protein kinase aurora-C; Serine/threonine-protein kinase 13; AIE2; AIK3; AIRK3; ARK3; STK13; Inner centromere protein
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Cat. No.: HY-P703463
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: AIK2; AIM1; AIRK2; ARK2; STK1; STK12; STK5
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Cat. No.: HY-P702867
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: AURKA; aurora kinase A; AIK; ARK1; AURA; BTAK; STK6; STK7; STK15; PPP1R47
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
