Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
MAPKAPK5
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "MAPKAPK5" in MCE Product Catalog:
Research Areas:
SM1-71 (compound 5) is a potent TAK1 inhibitor, with a Ki of 160 nM, it also can covalently inhibit MKNK2, MAP2K1/2/3/4/6/7, GAK, AAK1, BMP2K, MAP3K7, MAPKAPK5, GSK3A/B, MAPK1/3, SRC, YES1, FGFR1, ZAK (MLTK), MAP3K1, LIMK1 and RSK2. SM1-71 can inhibit proliferation of multiple cancer cell lines .
Target:
PROTACs CDK AAK1 Cyclin G-associated Kinase (GAK) Salt-inducible Kinase (SIK) LIM Kinase (LIMK) Wee1 SnRK
Research Areas:
RSS0680 is a small noncoding RNA (sRNA) targeting the mRNA ribosome binding site (RBS) and a PROTAC. RSS0680 competitively binds to RBS through the conserved CCUCCUCCC anti-Shine-Dalgarno (aSD) sequence and inhibits the translation initiation of target genes. RSS0680 can interact with the DUF1127 protein CcaF1, regulate its own stability and participate in bacterial oxidative stress defense, enhancing the host's resistance to heat shock and oxidative damage by affecting pathways such as C1 metabolism and pyruvate dehydrogenase complex. RSS0680 degrades AAK1, CDK1, CDK16, CDK2, CDK4, CDK6, EIF2AK4, GAK, LATSl, LIMK2, MAPK6, MAPKAPK5, MARK2, MARK4, MKNK2, NEK9, RPS6KB1, SIK2, SNRK, STK17A, STK17B, STK35, and WEEl. RSS0680 can be used to study diseases or disorders mediated by aberrant kinase activity and regulatory mechanisms of noncoding RNAs in α-proteobacteria[1][2].
Cat. No.: HY-RS08135
Target:
Research Areas:
MAPKAPK5 Human Pre-designed siRNA Set A contains three designed siRNAs for MAPKAPK5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23581
Target:
Research Areas:
Mapkapk5 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mapkapk5 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17135
Target:
Research Areas:
Mapkapk5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mapkapk5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W782935
CAS No.: 1195065-29-2
Target:
Research Areas:
MAPKAPK5-IN-1 is a substitutedtriazolopyrazine or imidazopyrazine compound and MAPKAPK5 inhibitor.MAPKAPK5-IN-1 can be used for the research of rheumatoid arthritis .
Cat. No.: HY-P702664
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: MAPKAPK5; MAPK activated protein kinase 5; MK5; MK-5; NCFD; PRAK; MAPKAP-K5
Species:
Source:
Cat. No.: HY-P85333A
Synonyms: MAPKAPK5; PRAK; MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPKAP kinase 5; MAPKAP-K5; MAPKAPK-5; MK-5; MK5; p38-regulated/activated protein kinase; PRAK
Cat. No.: HY-P74621
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MAP kinase-activated protein kinase 5; MAPKAP-K5; MK5; PRAK
Species:
Source:
Cat. No.: HY-P703736
Purity: ≥ 90%, as determined by reducing SDS-PAGE.;≥ 95%, as determined by HPLC.
Species:
Source:
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
