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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
MHC class II molecules
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "MHC class II molecules" in MCE Product Catalog:
Cat. No.: HY-P99613
CAS No.: 2231068-83-8
Synonyms: MK-4280; Mavezelimab
Cat. No.: HY-P11303
CAS No.: 161147-59-7
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Cat. No.: HY-157269
CAS No.: 1069110-72-0
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J10-1 is a hapten small molecule. J10-1 accelerates peptide exchange in MHC class II molecules in an HLA-DM-independent manner, and its effect is not affected by the polymorphism of the P1 pocket of MHC class II molecules. J10-1 enhances the processes of peptide dissociation, peptide binding and peptide association of MHC class II molecules on the surface of B cells. J10-1 can be used for research on immunoregulation .
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1-Adamantaneethanol is an allele-selective MHC II class molecule loading enhancer (MHC loading enhancer, MLE) that enhances peptide loading and ligand exchange of HLA-DR molecules. 1-Adamantaneethanol targets the polymorphic P1 pocket of HLA-DR molecules and preferentially acts on HLA-DR subtypes with Gly at position β86, thereby stabilizing the peptide-receptor conformation and accelerating antigen loading. 1-Adamantaneethanol can be used in studies related to MHC II antigen presentation, peptide vaccines, adaptive immunity and tumor immunity .
Cat. No.: HY-P5453
CAS No.: 646997-09-3
CFP10 (71–85) is a biological active peptide. (CFP1071–85, that elicited IFN-γ production and CTL activity by both CD4+ and CD8+ T cells from persons expressing multiple MHC class II and class I molecules)
Cat. No.: HY-P2525
CAS No.: 245124-26-9
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Cat. No.: HY-157171
CAS No.: 126530-17-4
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Ac-YR-NH2 is a small molecule modulator of MHC class II antigen presentation. Ac-YR-NH2 can influence peptide binding by MHC II to influence immune response .
Cat. No.: HY-P10246
CAS No.: 139644-18-1
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Cat. No.: HY-W179151
CAS No.: 105026-81-1
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N-Octanoyl dopamine is superior to dopamine in protecting graft contractile function when administered to the heart transplant recipients from brain-dead donors. N-Octanoyl dopamine inhibits cytokine production in activated T-cells and diminishes MHC-class-II expression as well as adhesion molecules in IFNγ-stimulated endothelial cells .
Cat. No.: HY-P2507
CAS No.: 508230-31-7
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Cat. No.: HY-P10525
CAS No.: 167278-49-1
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Cat. No.: HY-168384
CAS No.: 875158-73-9
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M04 is an agonist of STING. It induces the expression of the IFN reporter gene in HEK293T cells expressing wild-type human STING, but does not induce this expression in HEK293T cells expressing the R71H-G230A-R293Q (HAQ) STING variant or in mouse RAW 264.7 cells, indicating that its activity is dependent on allelic and species variations. M04 induces the production of TNF-α, IL-10, IL-1β, and IL-12p70 in human peripheral blood mononuclear cells (PBMCs). At a concentration of 50 µM, M04 stimulates dendritic cells isolated from PBMCs to express the MHC class II cell surface receptor HLA-DR and co-stimulatory molecules CD40, CD80, and CD86, and also enhances their ability to activate T cells in an ex vivo assay. M04 can be used in research on inflammatory immune diseases .
Cat. No.: HY-W387035
CAS No.: 2799-15-7
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D-α-Methyl DOPA is an inhibitor of the binding of DQ8 peptide to MHC class II molecules. D-α-Methyl DOPA occupies a pocket along the DQ8 peptide binding groove. D-α-Methyl DOPA inhibits the binding of a DQ8 peptide to an MHC class II molecule for presentation to CD4 + T cells, thereby slowing the development or progression of type 1 diabete or celiac disease .
Cat. No.: HY-171239
CAS No.: 656831-19-5
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Ste2Cys is a diacylglycerol cysteine-type immunologic adjuvant lipid molecule. Ste2Cys can bind to TLR2 and activate NF-κB signaling pathway. Ste2Cy can upregulate the expression of MHC II class molecules on the surface of mouse bone marrow-derived D1 dendritic cells. Ste2Cys can be used for research of the development of immunologic vaccines .
Cat. No.: HY-P705359
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HLA-A; MHC class 1 Antigen; Major Histocompatibility Complex, class I, A; MHC classI Antigen; HLA class I Histocompatibility Antigen, A Alpha Chain; Lymphocyte Antigen; MHC class I Antigen HLA-A Heavy Chain; HLA-A*6602 Antigen; Leukocyte Antigen class I-A; HLA-Aw34.2 Antigen; HLAA; HLA-A-6802 Protein; Major Histocompatibility Complex class I HLA-A-32 Protein; HLA-A-0203 Protein; HLA class I Histocompatibility Antigen, A-1 Alpha Chain; MHC class1 Antigen; HLA class I Histocompatibility Antigen A Alpha Chain; Leukocyte Antigen; Signal Peptide Alpha1 And Alpha2 Domain; HLA-A26.4 Antigen; HLA class I Histocompatibility Antigen; HLA-A10SA Antigen; MHC HLA-A Cell Surface Glycoprotein; MHC class I HLA-A; HLA class I A Locus Antigen A*68new; HLA-A26.3 Antigen; MHC class I Human Leukocyte Antigen; HLA-A30.2 Antigen; Ig-Like Domain-Containing Protein; HLA-A2new Protein; MHC class I Antigen Null Protein; Leucocyte Antigen; HLA-A Alpha1 And Alpha2 Domains; HLA-A9HH Antigen; MHC class I Antigen Heavy Chain; MHC class I Anti; Leucocyte Antigen A Alpha Chain; HLA-A29 Variant; Truncated MHC class I Antigen; HLA-A25 Protein; Truncated MHC class I Protein; MHC Alpha Chain; MHC class I Antigen Precusor; HLA-A*02:01NEW; MHC class I Protein (HLA-A); HLA-A Protein; HLA-A Locus Alpha 2 Domain; HLA class I A; Lymphocyte Antigen M7-A2.2; Alpha1 Domain; MHC class I Antigen R69772; MHC class I; Human Leukocyte Antigen A; HLA-A*24var; HLA-A*24:02:01:01 Variant; HLA-A*0210; MHC class I Antigen HLA-A; HLA-A*2903; Cell Surface Glycoprotein; HLA-A-6802; Leucocyte Antigen class I; HLA-A-0203; Leukocyte Antigen class I; HLA-A*3303; Transplantation Antigen; HLA-A*0218; HLA class I Heavy Chain; HLA-A2 SLU; HLA-A11 Antigen A11.2; HLA-A-02; MHC class I Antigen A; HLA-A-32; MHC Leukocyte Antigen; HLA-A30; MHC class II Antigen; HLA-A25; MHC class I Antigene; HLA-A26; Cell Surface Antigen; HLA-A*; HLA-A Alpha 1 Domain; HLA-A2; MHC class I Antigen; A1102; MHC class I Protein; Hla-A; HLA class I Antigen; HLA-H; Leucocyte Antigen A; HLA_A; MCH class I Antigen; HLA; B2M; Beta 2-Microglobulin; Beta-2-Microglobulin; Beta-2-Microglobin; Beta Chain Of MHC class I molecules; AMYLD6; Beta 2-Microglobulin Protein; MHC1D4; Human Nkt Tcr Alpha Chain; IMD43; Human Nkt Tcr Beta Chain
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
