11 Results for "

MRP3

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "MRP3" in MCE Product Catalog:

Cat. No.: HY-113083
CAS No.: 16110-10-4
Purity:  ≥99.0%
Synonyms: APAP-glu
Acetaminophen glucuronide (APAP-glu) is an inactive glucuronide metabolite of Acetaminophen (HY-66005) . Acetaminophen is a selective cyclooxygenase-2 (COX-2) inhibitor and a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor [3] .
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Cat. No.: HY-D1078
CAS No.: 127770-45-0
5 (6)-Carboxy-2',7'-dichlorofluorescein diacetate is a fluorescein-based reactive oxygen species (ROS) probe and also a MRP2 substrate. 5 (6)-Carboxy-2',7'-dichlorofluorescein diacetate serves as a substrate for intracellular esterases, which cleave its acetate groups to generate a fluorescent product capable of detecting intracellular ROS. 5 (6)-Carboxy-2',7'-dichlorofluorescein diacetate is ATP-dependent and is transported via a single MRP2 binding site; it competes with LTC4 for MRP2 binding sites and inhibits MRP2-mediated LTC4 transport (Ex/Em = 496/525 nm) [3] .
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Cat. No.: HY-W702907
CAS No.: 1346599-56-1
Target:  

P-glycoprotein

Research Areas:  

Metabolic Disease

DM-4103 is a major metabolite of Tolvaptan (HY-17000) that is metabolized primarily by the CYP3A4 enzyme in the liver. DM-4103 inhibits the ability of human liver transporters NTCP, BSEP, MRP2, MRP3, MRP4 (IC50 values are 16.3, 4.15, 51.0, 44.6, 4.26 μM, respectively) and bile acid transport in SCHH cells. DM-4103 can be used in the study of autosomal dominant polycystic kidney disease (ADPKD) .
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Cat. No.: HY-W702908
CAS No.: 1346599-75-4
Target:  

P-glycoprotein

Research Areas:  

Metabolic Disease

DM-4107 is a major metabolite of Tolvaptan (HY-17000) that is metabolized primarily by the CYP3A4 enzyme in the liver. DM-4107 inhibits the ability of human liver transporters NTCP, BSEP, MRP3, MRP4 (IC50 values are 95.6, 119, 61.2, 37.9 μM, respectively) and bile acid transport in SCHH cells. DM-4107 can be used in the study of autosomal dominant polycystic kidney disease (ADPKD) .
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Cat. No.: HY-P83832A
Synonyms: MLP2; MRP3; ABC31; MOAT-D; cMOAT2; EST90757

Host:  

Mouse

Application:  

IHC-P, FC, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P83832
Synonyms: MLP2; MRP3; ABC31; MOAT-D; cMOAT2; EST90757

Host:  

Mouse

Application:  

IHC-P, FC, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-N9440
CAS No.: 66695-14-5
Target:  

Drug Metabolite

Research Areas:  

Inflammation/Immunology Cancer

7-Hydroxycoumarin glucuronide is a transport substrate and main human coumarin metabolite. 7-Hydroxycoumarin glucuronide undergoes ATP-dependent efflux transport via MRP3 and MRP4. 7-Hydroxycoumarin glucuronide undergoes active transport processes for urinary excretion and is primarily excreted into urine in humans.
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Cat. No.: HY-RS26480
Research Areas:  

Others

Abcc3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Abcc3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-113083R
CAS No.: 16110-10-4
Synonyms: APAP-glu (Standard)
Acetaminophen glucuronide (Standard) is the analytical standard of Acetaminophen glucuronide. This product is intended for research and analytical applications. Acetaminophen glucuronide (APAP-glu) is an inactive glucuronide metabolite of Acetaminophen (HY-66005) . Acetaminophen is a selective cyclooxygenase-2 (COX-2) inhibitor and a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor [3] .
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Cat. No.: HY-RS00062
Research Areas:  

Others

ABCC3 Human Pre-designed siRNA Set A contains three designed siRNAs for ABCC3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS19977
Research Areas:  

Others

Abcc3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Abcc3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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