Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
MRP3
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "MRP3" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-D0194
CAS No.: 111843-78-8
Target:
Research Areas:
5 (6)-Carboxy-2',7'-dichlorofluorescein is a fluorescent probe substrate that acts on MRP1 and MRP3/Mrp3, passively diffuses across cell membranes, and is actively effluxed by MRP1 in MRP1-positive cells. 5 (6)-Carboxy-2',7'-dichlorofluorescein is transported across membranes in an ATP-dependent manner, but does not stimulate ATPase activity .
Cat. No.: HY-156701
CAS No.: 1428988-21-9
Target:
Research Areas:
BAY-1128688 is a selective, orally active aldo-keto reductase family 1 member C3 (AKR1C3) inhibitor with an IC50 of 1.4 nM. BAY-1128688 inhibits OATP, BSEP, MRP4, NTCP, UGT1A1, MRP2, and MRP3. BAY-1128688 induces reactive oxygen species (ROS) production, inhibits the mitochondrial electron transport chain, and increases circulating androsterone, etiocholanolone, dihydrotestosterone, and serum bilirubin concentrations. BAY-1128688 alters bilirubin disposition, leading to elevated plasma bilirubin, independent of liver injury. BAY-1128688 can be used in research on endometriosis and polycystic ovary syndrome [3].
Cat. No.: HY-125737
Synonyms: 15-Deoxy-Δ12,14-PGJ2 Glutathione
Target:
Research Areas:
15-Deoxy-Δ12,14-prostaglandin J2 glutathione (15-Deoxy-Δ12,14-PGJ2 Glutathione) is a glutathione conjugate that can be obtained by the reaction of 15-deoxy-Δ12,14-prostaglandin J2 with glutathione. 15-Deoxy-Δ12,14-prostaglandin J2 glutathione is an ATP-dependent transport substrate of MRP1 and MRP3. 15-Deoxy-Δ12,14-prostaglandin J2 glutathione can be used for breast cancer research .
Cat. No.: HY-W702907
CAS No.: 1346599-56-1
Target:
Research Areas:
DM-4103 is a major metabolite of Tolvaptan (HY-17000) that is metabolized primarily by the CYP3A4 enzyme in the liver. DM-4103 inhibits the ability of human liver transporters NTCP, BSEP, MRP2, MRP3, MRP4 (IC50 values are 16.3, 4.15, 51.0, 44.6, 4.26 μM, respectively) and bile acid transport in SCHH cells. DM-4103 can be used in the study of autosomal dominant polycystic kidney disease (ADPKD) .
Cat. No.: HY-W702908
CAS No.: 1346599-75-4
Target:
Research Areas:
DM-4107 is a major metabolite of Tolvaptan (HY-17000) that is metabolized primarily by the CYP3A4 enzyme in the liver. DM-4107 inhibits the ability of human liver transporters NTCP, BSEP, MRP3, MRP4 (IC50 values are 95.6, 119, 61.2, 37.9 μM, respectively) and bile acid transport in SCHH cells. DM-4107 can be used in the study of autosomal dominant polycystic kidney disease (ADPKD) .
Cat. No.: HY-N9440
CAS No.: 66695-14-5
Target:
Research Areas:
7-Hydroxycoumarin glucuronide is a transport substrate and main human coumarin metabolite. 7-Hydroxycoumarin glucuronide undergoes ATP-dependent efflux transport via MRP3 and MRP4. 7-Hydroxycoumarin glucuronide undergoes active transport processes for urinary excretion and is primarily excreted into urine in humans.
Cat. No.: HY-RS26480
Target:
Research Areas:
Abcc3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Abcc3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00062
Target:
Research Areas:
ABCC3 Human Pre-designed siRNA Set A contains three designed siRNAs for ABCC3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19977
Target:
Research Areas:
Abcc3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Abcc3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
