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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
Monomethyl Dolastatin-10
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "Monomethyl Dolastatin-10" in MCE Product Catalog:
61
61 Cited Publications
Synonyms: MMAE; SGD-1010
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Research Areas:
Monomethyl auristatin E (MMAE; SGD-1010) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types.
Cat. No.: HY-15162R
CAS No.: 474645-27-7
Synonyms: MMAE (Standard); SGD-1010 (Standard); Vedotin (Standard)
Research Areas:
Monomethyl auristatin E (MMAE) (Standard) is the analytical standard of Monomethyl auristatin E (HY-15162). This product is intended for research and analytical applications. Monomethyl auristatin E is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) against several different cancer types .
Synonyms: DemethylDolastatin 10; Monomethylauristatin D; Monomethyl Dolastatin 10
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Research Areas:
MMAD is a potent tubulin inhibitor, is a toxin payload in antibody agent conjugates (ADCs).
Cat. No.: HY-126492
CAS No.: 1415329-13-3
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Research Areas:
Vat-Cit-PAB-Monomethyl Dolastatin 10 is a agent-linker conjugate for ADC with potent antitumor activity by using Monomethyl Dolastatin 10 (a potent tubulin inhibitor), linked via the ADC linker Vat-Cit-PAB.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
