12 Results for "

NCI-H1650

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "NCI-H1650" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P99041
CAS No.: 339177-26-3
Synonyms: ABX-EGF

Target:  

EGFR

Research Areas:  

Cancer

Panitumumab (ABX-EGF) is a fully human IgG2 anti-EGFR monoclonal antibody with anti-tumor activity. Panitumumab inhibits tumor cell proliferation, survival and angiogenesis. Panitumumab can be used in the research of cancers, such as colon cancer .
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Cat. No.: HY-W250111
CAS No.: 83512-85-0
Carboxymethyl chitosan is a derivative of chitosan. Carboxymethyl chitosan inhibits Apoptosis and ROS. Carboxymethyl chitosan increases the expression of Bcl-2 and reduces the expression of Bax, cytochrome c and caspase-3. Carboxymethyl chitosan inhibits the migration of various cells. Carboxymethyl chitosan exerts antitumor effects on Lewis tumors and hepatocarcinoma .
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Cat. No.: HY-P99041A

Target:  

EGFR

Research Areas:  

Cancer

Panitumumab (anti-EGFR) is a fully human IgG2 anti-EGFR monoclonal antibody with anti-tumor activity. Panitumumab (anti-EGFR) inhibits tumor cell proliferation, survival and angiogenesis. Panitumumab (anti-EGFR) can be used in the research of cancers, such as colon cancer .
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Cat. No.: HY-N2039
CAS No.: 80952-72-3
20(R)-Ginsenoside Rg2 shows inhibitory effects on lung cancer NCI-H1650 cells. Anti-cancer activities .
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Cat. No.: HY-N1326
CAS No.: 4290-13-5
Synonyms: Santamarin; Balchanin
Santamarine (Santamarin; Balchanin) is a sesquiterpene lactone found in Artemisia scoparia. Santamarine shows anti-inflammatory, antioxidant, anticancer and anti-photoaging activities. Santamarine suppresses UVA-induced phosphorylation of JNK and p38 MAPK, nuclear translocation of phosphorylated c-Fos and c-Jun, and AP-1-mediated MMP-1 transcription and secretion. Santamarine suppresses NF-κB signaling, iNOS, COX-2, TNF-α, and IL-1β production. Santamarine inhibits thioredoxin reductase activity, induces ROS production, mitochondrial apoptosis, G2/M cell cycle arrest, and DNA damage, and reduces cancer cell growth. Santamarine can be used for the photoaging, inflammatory diseases and cancer .
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Cat. No.: HY-P99041B
CAS No.: 339177-26-3
Synonyms: ABX-EGF (powder)

Target:  

EGFR

Research Areas:  

Cancer

Panitumumab (ABX-EGF) (powder) is a fully human IgG2 anti-EGFR monoclonal antibody with anti-tumor activity. Panitumumab (powder) inhibits tumor cell proliferation, survival and angiogenesis. Panitumumab (powder) can be used in the research of cancers, such as colon cancer .
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Cat. No.: HY-N2039R
CAS No.: 80952-72-3
20(R)-Ginsenoside Rg2 (Standard) is the analytical standard of 20(R)-Ginsenoside Rg2. This product is intended for research and analytical applications. 20(R)-Ginsenoside Rg2 shows inhibitory effects on lung cancer NCI-H1650 cells. Anti-cancer activities .
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Cat. No.: HY-177967
CAS No.: 1616473-67-6
Target:  

Drug Derivative

Research Areas:  

Cancer

Antitumor agent-209 (Compound 10g), a quinolone derivative, is an antitumor agent. Antitumor agent-209 can inhibit proliferation of HCT-116, RKO, DLD1, HepG2, BGC-823, NCI-H1650 and SK-OV-3 cells with IC50 values of 0.37, 0.58, 0.81, 0.79, 0.89, 0.78 and 0.89 μM .
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Cat. No.: HY-W098807
CAS No.: 178984-50-4
Target:  

Drug Derivative

Research Areas:  

Cancer

4-Chloro-7-ethoxyquinoline (Compound 9a), a quinolone derivative, is an anticancer agent. 4-Chloro-7-ethoxyquinoline can inhibit proliferation of HCT-116, RKO, DLD1, HepG2, BGC-823, NCI-H1650 and SK-OV-3 cells with IC50 values of 3.16, 3.87, 2.75, 2.66, 3.91, 3.34 and 3.46μM .
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Cat. No.: HY-146046
CAS No.: 2411579-53-6
Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

Antitumor agent-56 (Compound 33) is a triptolide derivative with antitumor, anti-inflammatory and NO release activities. Antitumor agent-56 significantly inhibits the growth of melanoma. Antitumor agent-56 is orally active .
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Cat. No.: HY-N17466
CAS No.: 1536262-88-0
(7S,7′R,8S,8′S)-neo-Olivil is a lignan present in the rhizome of Iris tectorum. (7S,7′R,8S,8′S)-neo-Olivil shows no significant cytotoxicity against human tumor cells at a concentration of 10 μM .
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Cat. No.: HY-184434
CAS No.: 3064280-41-4
Research Areas:  

Cancer

PRMT5-IN-57 is an orally active andselective MTA-cooperative PRMT5 inhibitor, with an IC50 of 8.39 nM against PRMT5/MTA complex. PRMT5-IN-57 exhibits potent and selective antiproliferative activity against MTAP-null cancer cells. PRMT5-IN-57 demonstrates significant in vivo antitumor efficacy in an HCT116 MTAP-/- CDX model. PRMT5-IN-57 can be used for the research of MTAP-deleted cancers .
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