80952-72-3
80952-72-3
Chemical Structure
20(R)-Ginsenoside Rg2
- CAS No.: 80952-72-3
- Formula:C42H72O13
- Molecular Weight:785.01
IUPAC Name: (2S,3R,4R,5R,6S)-2-(((2R,3R,4S,5S,6R)-2-(((3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-17-((R)-2-hydroxy-6-methylhept-5-en-2-yl)-4,4,8,10,14-pentamethylhexadecahydro-1H-cyclopenta[a]phenanthren-6-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H
InChIKey: AGBCLJAHARWNLA-RPNKVCLTSA-N
SMILES: C[C@]12[C@@]3(C)[C@]([C@](CC[C@H](O)C4(C)C)(C)[C@@]4([H])[C@@H](O[C@H]5[C@H](O[C@H]6[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O6)[C@@H](O)[C@H](O)[C@@H](CO)O5)C3)([H])C[C@@H](O)[C@]1([H])[C@]([C@@](CC/C=C(C)/C)(O)C)([H])CC2
Biological Activity: 20(R)-Ginsenoside Rg2 shows inhibitory effects on lung cancer NCI-H1650 cells. Anti-cancer activities[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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20(R)-Ginsenoside Rg2 | 99.88% | 20(R)-Ginsenoside Rg2 shows inhibitory effects on lung cancer NCI-H1650 cells. Anti-cancer activities. | ||||||||||||||||||||
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20(R)-Ginsenoside Rg2 (Standard) | ≥98% | 20(R)-Ginsenoside Rg2 (Standard) is the analytical standard of 20(R)-Ginsenoside Rg2. This product is intended for research and analytical applications. 20(R)-Ginsenoside Rg2 shows inhibitory effects on lung cancer NCI-H1650 cells. Anti-cancer activities. | ||||||||||||||||||||
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Ginsenoside Re (Standard) | ≥98% | Ginsenoside Re (Standard) is the analytical standard of Ginsenoside Re. This product is intended for research and analytical applications. Ginsenoside Re (Ginsenoside B2) is an extract from Panax notoginseng. Ginsenoside Re decreases the β-amyloid protein (Aβ). Ginsenoside Re plays a role in antiinflammation through inhibition of JNK and NF-κB. | ||||||||||||||||||||
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Ginsenoside Rf | 99.48% | Ginsenoside Rf is a trace component of ginseng root. Ginsenoside Rf inhibits N-type Ca2+ channel. | ||||||||||||||||||||
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Ginsenoside Rg2 (Standard) | ≥98% | Ginsenoside Rg2 (Standard) is the analytical standard of Ginsenoside Rg2. This product is intended for research and analytical applications. Ginsenoside Rg2 is one of the major active components of ginseng. Ginsenoside Rg2 inhibits VCAM-1 and ICAM-1 expressions stimulated with lipopolysaccharide (LPS). Ginsenoside Rg2 also reduces Aβ1-42 accumulation. | ||||||||||||||||||||
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Ginsenoside Rh1 | 98.72% | Ginsenoside Rh1 (Prosapogenin A2) inhibits the expression of PPAR-γ, TNF-α, IL-6, and IL-1β. | ||||||||||||||||||||
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Ginsenoside Rg6 | 99.87% | Ginsenoside Rg6 inhibits TNF-α-induced NF-κB transcriptional activity with an IC50 of 29.34 μM in HepG2 cells. Ginsenoside Rg6 also exhibits apoptosis-inducing effect. | ||||||||||||||||||||
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Notoginsenoside R2 | 99.80% | Notoginsenoside R2 (20(S)-Notoginsenoside R2; Ginsenoside Ng-R2) is an orally active notoginsenoside. Notoginsenoside R2 activates P90RSK and Nrf2 via the MEK1/2-ERK1/2 pathway to inhibit 6-OHDA-induced apoptotic damage in nerve cells. Notoginsenoside R2 upregulates SOX8/β-catenin by reducing miR-27a, thereby suppressing Aβ25-35-induced neuronal apoptosis and inflammatory responses. Notoginsenoside R2 alleviates lipid accumulation and mitochondrial dysfunction in diabetic nephropathy by inhibiting c-Src. Notoginsenoside R2 alleviates hepatic fibrosis by inducing hepatic stellate cell senescence and inhibiting the inflammatory microenvironment via JAK/STAT3 suppression. Notoginsenoside R2 can be used in research related to Parkinson's disease, Alzheimer's disease, diabetic nephropathy and hepatic fibrosis. | ||||||||||||||||||||
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(20R)-Ginsenoside Rh1 (Standard) | ≥98% | (20R)-Ginsenoside Rh1 (Standard) is the analytical standard of (20R)-Ginsenoside Rh1 (HY-N1400). This product is intended for research and analytical applications. (20R)-Ginsenoside Rh1 is the R-isomer of Ginsenoside Rh1 (HY-N0604), and it is found in red ginseng, ginseng, and other sources. (20R)-Ginsenoside Rh1 inhibits thrombin-induced conversion of fibrinogen to fibrin, exerting anticoagulant and antithrombotic effects. | ||||||||||||||||||||
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20(R)-Notoginsenoside R2 | 99.75% | 20(R)-Notoginsenoside R2 is an isolated notoginsenoside from Panax notoginseng. | ||||||||||||||||||||
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Ginsenoside F4 | 98.54% | Ginsenoside F4 (GF4), ginseng saponinis, isolated from notoginseng or red ginseng. Ginsenoside F4 (GF4) has inhibitory effect on human lymphocytoma JK cell by inducing its apoptosis. Ginsenoside F4 (GF4) inhibits matrix metalloproteinase 13 (MMP 13) expression in IL-1β-treated chondrocytes and blocks cartilage breakdown in rabbit cartilage tissue culture, shows therapeutic potential for preventing cartilage collagen matrix breakdown in diseased tissues. | ||||||||||||||||||||
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Gynosaponin I | Gynosaponin I (compound 1) is a natural product that can be found in Gynostemma pentaphyllum. | |||||||||||||||||||||
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