9 Results for "

Noscapine

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "Noscapine" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-13716
CAS No.: 128-62-1
Purity:  99.98%
Synonyms: (S,R)-Noscapine
Noscapine ((S,R)-Noscapine) is an orally active phthalideisoquinoline alkaloid with potent antitussive. Noscapine exerts its antitussive effects by activating sigma opioid receptors and is a non-competitive Bradykinin inhibitor. Noscapine disrupts microtubule dynamics, induces mitotic arrest and apoptosis. Noscapine possesses anticancer, neuroprotective, anti-inflammatory activities, and can cross the blood-brain barrier .
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2
2 Cited Publications
Cat. No.: HY-13716A
CAS No.: 912-60-7
Purity:  99.87%
Synonyms: (S,R)-Noscapine hydrochloride
Noscapine ((S,R)-Noscapine) hydrochloride is an orally active phthalideisoquinoline alkaloid with potent antitussive. Noscapine hydrochloride exerts its antitussive effects by activating sigma opioid receptors and is a non-competitive Bradykinin inhibitor. Noscapine hydrochloride disrupts microtubule dynamics, induces mitotic arrest and apoptosis. Noscapine hydrochloride possesses anticancer, neuroprotective, anti-inflammatory activities, and can crosse the blood-brain barrier .
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Cat. No.: HY-W019151
CAS No.: 569-31-3
Meconine is the urinary metabolite of Noscapine (HY-13716) and also a phase I metabolite of Bromonoscapine. Meconine can serve as a complementary biomarker in addition to opioid metabolites .
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Cat. No.: HY-W019151R
CAS No.: 569-31-3
Meconine (Standard) is the analytical standard of Meconine (HY-W019151). This product is intended for research and analytical applications. Meconine is the urinary metabolite of Noscapine (HY-13716) and also a phase I metabolite of Bromonoscapine. Meconine can serve as a complementary biomarker in addition to opioid metabolites .
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Cat. No.: HY-W019151S
CAS No.: 29809-15-2
Meconine-d3 is the deuterium labeled Meconine (HY-W019151). Meconine is an endogenous metabolite of Noscapine (HY-13716). Meconine is the major metabolite in all three species, accounting for about 3, 8 and 2% of the dose in the first 24 h urines of rats, rabbits and humans, respectively. Meconine can be used as a marker to detect illicit opiate use.
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Cat. No.: HY-172915
CAS No.: 2531685-87-5
Target:  

MDM-2/p53 DNA-PK Apoptosis

Research Areas:  

Cancer

p53 Stabilizer 2 is a 9'-cycloheptylselenomethyl-noscapine derivative and DNA-PKcs-dependent p53 stabilizer with low tubulin-binding affinity.p53 Stabilizer 2 induces S-phase arrest and apoptosis in cancer cells.p53 Stabilizer 2 can be used for the research of cancer .
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Cat. No.: HY-13716R
CAS No.: 128-62-1
Synonyms: (S,R)-Noscapine (Standard)
Noscapine (Standard) is the analytical standard of Noscapine. This product is intended for research and analytical applications. Noscapine ((S,R)-Noscapine) is an orally active phthalideisoquinoline alkaloid with potent antitussive. Noscapine exerts its antitussive effects by activating sigma opioid receptors and is a non-competitive Bradykinin inhibitor. Noscapine disrupts microtubule dynamics, induces mitotic arrest and apoptosis. Noscapine possesses anticancer, neuroprotective, anti-inflammatory activities, and can cross the blood-brain barrier [4] .
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Cat. No.: HY-13716S
CAS No.: 1217680-57-3
Noscapine- 13C,d3 is a 13C- labeled and deuterated labeled Noscapine . Noscapine ((S,R)-Noscapine) is an orally active phthalideisoquinoline alkaloid with potent antitussive. Noscapine exerts its antitussive effects by activating sigma opioid receptors and is a non-competitive Bradykinin inhibitor. Noscapine disrupts microtubule dynamics, induces mitotic arrest and apoptosis. Noscapine possesses anticancer, neuroprotective, anti-inflammatory activities, and can cross the blood-brain barrier .
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Cat. No.: HY-W746289
CAS No.: 521-40-4
Narcotoline, a phenylpyridine isoquinoline alkaloid, is a by-product in the biosynthetic pathway of Noscapine (HY-13716). Narcotoline can be used to study the metabolic regulatory agents of Noscapine .
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