8 Results for "

OMTX705

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "OMTX705" in MCE Product Catalog:

Cat. No.: HY-148127
CAS No.: 1802499-21-3
Purity:  99.29%
Research Areas:  

Cancer

TAM558 is a payload molecule used for the synthesis of OMTX705. OMTX705 is a humanized anti-fibroblast-activating protein (FAP) antibody conjugated to the cytolysin TAM470 (HY-148128), with antitumor activity .
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Cat. No.: HY-148128
CAS No.: 1802498-63-0
Purity:  98.53%
Research Areas:  

Cancer

TAM470 is a novel cytolysin, inhibiting tubulin polymerization and microtubule depolymerization. TAM470 can be used in the synthesis of OMTX705 as payload molecule, OMTX705 is a novel FAP-targeting antibody-drug conjugates (ADCs) with antitumor activity .
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Cat. No.: HY-P991995
Synonyms: OMTX705 antibody

Target:  

ADC Antibodies FAP

Research Areas:  

Cancer

OMTX005 (OMTX705 antibody) is a humanized anti-FAP IgG1 monoclonal antibody that specifically binds to human (EC50: 0.33 nM)/mouse (EC50: 0.14 nM) FAP proteins and FAP-positive cells. OMTX005 exhibits no cytotoxicity when used alone and fails to induce an increase in caspase 3/7 activity in relevant cells. OMTX005 can be used to synthesize the ADC molecule OMTX705 for tumor research .
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Cat. No.: HY-400687
Target:  

Drug Intermediate

Research Areas:  

Cancer

TAM558 intermediate-1 is an intermediate in the synthesis of TAM558 (HY-148127).TAM558 is the payload molecule used in the synthesis of OMTX705.OMTX705 is a humanized anti-fibroblast activation protein (FAP) antibody that binds to the cytolysin TAM470 (HY-148128) and has anti-tumor activity .
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Cat. No.: HY-400688
CAS No.: 2135877-76-6
Target:  

ADC Payloads

Research Areas:  

Cancer

TAM558 intermediate-24 is an intermediate in the synthesis of TAM558 (HY-148127).TAM558 is the payload molecule used in the synthesis of OMTX705.OMTX705 is a humanized anti-fibroblast activation protein (FAP) antibody that binds to the cytolysin TAM470 (HY-148128) and has anti-tumor activity .
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Cat. No.: HY-400689
Target:  

Drug Intermediate

Research Areas:  

Cancer

TAM558 intermediate-34 is an intermediate in the synthesis of TAM558 (HY-148127).TAM558 is the payload molecule used in the synthesis of OMTX705.OMTX705 is a humanized anti-fibroblast activation protein (FAP) antibody that binds to the cytolysin TAM470 (HY-148128) and has anti-tumor activity .
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Cat. No.: HY-400690
Target:  

Drug Intermediate

Research Areas:  

Cancer

TAM558 intermediate-4 is an intermediate in the synthesis of TAM558 (HY-148127).TAM558 is the payload molecule used in the synthesis of OMTX705.OMTX705 is a humanized anti-fibroblast activation protein (FAP) antibody that binds to the cytolysin TAM470 (HY-148128) and has anti-tumor activity .
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Cat. No.: HY-48564
CAS No.: 1415659-15-2
Target:  

ADC Payloads

Research Areas:  

Cancer

TAM558 intermediate-54 is an intermediate in the synthesis of TAM558 (HY-148127).TAM558 is the payload molecule used in the synthesis of OMTX705.OMTX705 is a humanized anti-fibroblast activation protein (FAP) antibody that binds to the cytolysin TAM470 (HY-148128) and has anti-tumor activity .
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