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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
OPP
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "OPP" in MCE Product Catalog:
4
Research Areas:
Farudodstat (ASLAN003) is an orally active and potent Dihydroorotate Dehydrogenase (DHODH) inhibitor with an IC50 of 35 nM for human DHODH enzyme. Farudodstat inhibits protein synthesis via activation of AP-1 transcription factors. Farudodstat induces apoptosis and substantially prolongs survival in acute myeloid leukemia (AML) xenograft mice .
Cat. No.: HY-P11106
CAS No.: 116355-81-8
Cat. No.: HY-118707
CAS No.: 14486-15-8
Synonyms: Met-met-met
Target:
Research Areas:
Trimethionine (Met-met-met) is an orally active tripeptide substrate of peptide transport systems. Trimethionine interacts with the triple-leucine-triple-threonine transport system and the oligopeptide permease (Opp) system in Escherichia coli, competing for uptake and transport processes. Trimethionine antagonizes the toxicity of threonine tripeptide and ornithine tripeptide, and competes with peptide-supported growth and amino acid source utilization processes in Escherichia coli strains. Trimethionine is taken up by Candida albicans via a carrier-mediated, energy-dependent manner, and is subsequently hydrolyzed into free methionine intracellularly. Trimethionine can be used in studies related to Candida albicans infections .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
