Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
Optn
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "Optn" in MCE Product Catalog:
Cat. No.: HY-165298
CAS No.: 2504949-52-2
DGY-09-192 is a PROTAC FGFR1/2 degrader (FGFR1: DC50 = 4.35 nM; FGFR2: DC50 = 70 nM). DGY-09-192 preferentially degrades wild-type FGFR1/2 and multiple FGFR2 fusion proteins (including FGFR2-PHGDH and FGFR2-OPTN). DGY-09-192 suppresses downstream FGFR signaling (reducing phosphorylation of FRS2 Y196 and ERK1/2 T202/Y204) in vitro and vivo. DGY-09-192 can be used for the study of FGFR-driven cancers .
Cat. No.: HY-RS09809
Target:
Research Areas:
OPTN Human Pre-designed siRNA Set A contains three designed siRNAs for OPTN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24621
Target:
Research Areas:
Optn Rat Pre-designed siRNA Set A contains three designed siRNAs for Optn gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18146
Target:
Research Areas:
Optn Mouse Pre-designed siRNA Set A contains three designed siRNAs for Optn gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P701320
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Optn; Huntingtin-Interacting Protein L; Prev. GLC1E; Huntingtin Yeast Partner L; FIP-2; HIP-7; FIP2; Tumor Necrosis Factor Alpha-Inducible Cellular Protein Containing Leucine Zipper Domains; HYPL; Transcrption Factor IIIA-Interacting Protein; HIP7; Glauco
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P83382
Synonyms: FIP2; GLC1E; HIP7; HYPL; NRP; Optn; Optineurin; E3-14.7K-interacting protein; Huntingtin yeast partner L; Huntingtin-interacting protein 7; Huntingtin-interacting protein L; NEMO-related protein; Optic neuropathy-inducing protein; Transcription factor IIIA-interacting protein; FIP-2; HIP-7; TFIIIA-IntP
Cat. No.: HY-P86607
Synonyms: FIP2; GLC1E; HIP7; HYPL; NRP; Optn; Optineurin; E3-14.7K-interacting protein; Huntingtin yeast partner L; Huntingtin-interacting protein 7; Huntingtin-interacting protein L; NEMO-related protein; Optic neuropathy-inducing protein; Transcription factor IIIA-interacting protein; FIP-2; HIP-7; TFIIIA-IntP
Cat. No.: HY-P83382A
Synonyms: FIP2; GLC1E; HIP7; HYPL; NRP; Optn; Optineurin; E3-14.7K-interacting protein; Huntingtin yeast partner L; Huntingtin-interacting protein 7; Huntingtin-interacting protein L; NEMO-related protein; Optic neuropathy-inducing protein; Transcription factor IIIA-interacting protein; FIP-2; HIP-7; TFIIIA-IntP
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
