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Results for "

PEX14

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

2

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-155531
    PEX5-PEX14 PPI-IN-2

    		Biochemical Assay Reagents Infection
    PEX5-PEX14 PPI-IN-2 (compound 12) is a PEX14-PEX5 protein-protein interaction (PPI) inhibitor. PEX5-PEX14 PPI-IN-2 inhibits PEX14-PEX5 PPI with EC50 values of 5 and 17 µM in T. b. brucei and HepG2 cells, respectively. PEX5-PEX14 PPI-IN-2 can be used in the research of diseases related to trypanosome infection .
    PEX5-PEX14 PPI-IN-2
  • HY-RS10345
    PEX14 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    PEX14 Human Pre-designed siRNA Set A contains three designed siRNAs for PEX14 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    PEX14 Human Pre-designed siRNA Set A
    PEX14 Human Pre-designed siRNA Set A
  • HY-155530
    PEX5-PEX14 PPI-IN-1

    		Bacterial Infection
    PEX5-PEX14 PPI-IN-1 (Compound 8) is a PEX14-PEX5 PPI inhibitor. PEX5-PEX14 PPI-IN-1 disrupts the PEX5-TbPEX14 PPI with a Ki of 53 μM. PEX5-PEX14 PPI-IN-1 inhibits the bloodstream form of T. b. brucei (EC50: 5 μM) .
    PEX5-PEX14 PPI-IN-1
  • HY-175517
    PEX5-PEX14 PPI-IN-3

    		Parasite Infection
    PEX5-PEX14 PPI-IN-3 (Compound 7) is an inhibitor of the PEX5-PEX14 protein-protein interaction (PPI) with an EC50 of 95 μM. PEX5-PEX14 PPI-IN-3 has an EC50 of 7.2 μM against Trypanosoma brucei (T. brucei). PEX5-PEX14 PPI-IN-3 exhibits low cytotoxicity towards HepG2 cells and possesses antiparasitic activity .
    PEX5-PEX14 PPI-IN-3
  • HY-182443
    PEX5-PEX14 PPI-IN-4

    		Parasite Infection
    PEX5-PEX14 PPI-IN-4 is a potent PEX14-PEX5 PPI inhibitor, with EC50 values of 7.78 μM, 27.5 μM and 9.31 μM against the protein-protein interactions of TbPEX14-PEX5, TcPEX14-PEX5 and HsPEX14-PEX5, respectively. PEX5-PEX14 PPI-IN-4 exhibits trypanocidal activity against Trypanosoma brucei rhodesiense and Trypanosoma cruzi. PEX5-PEX14 PPI-IN-4 shows cytotoxic activity against mammalian cells. PEX5-PEX14 PPI-IN-4 can be used in the research of human African trypanosomiasis and Chagas disease .
    PEX5-PEX14 PPI-IN-4

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