3 Results for "

Polyphosphoinositide

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Polyphosphoinositide" in MCE Product Catalog:

Cat. No.: HY-120589
CAS No.: 1310012-12-4
Purity:  98.07%
Target:  

mGluR

Research Areas:  

Neurological Disease

VU0360172 is a potent and selective mGlu5 receptor positive allosteric modulator with an EC50 value of 16 nM and a Ki of 195 nM, respectively. VU0360172 stimulates polyphosphoinositide (PI) hydrolysis in vivo, which is abrogated in mGlu5 receptors gene deleted mice . VU0360172 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No.: HY-107504
CAS No.: 1309976-62-2
Purity:  98.94%
Target:  

mGluR

Research Areas:  

Neurological Disease

VU0360172 hydrochloride is a potent and selective mGlu5 receptor positive allosteric modulator (PAM) with an EC50 value of 16 nM and a Ki of 195 nM, respectively. VU0360172 hydrochloride stimulates polyphosphoinositide (PI) hydrolysis in vivo, which is abrogated in mGlu5 receptors gene deleted mice .
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Cat. No.: HY-P2139
CAS No.: 139446-71-2
Research Areas:  

Others

Ranakinin is a NK1R agonist. Ranakinin inhibits the binding of selective NK1 radioligands to NK1 receptors. Ranakinin activates phospholipase C (Phospholipase C), thereby enhancing polyphosphoinositide hydrolysis. Ranakinin stimulates inositol phosphate production and reduces membrane polyphosphoinositide levels. Ranakinin stimulates corticosterone and aldosterone secretion .
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