53 Results for "

Programmed death-ligand 1 (PD-L1)

" in MedChemExpress (MCE) Product Catalog:
Products (53)

53 Results for "Programmed death-ligand 1 (PD-L1)" in MCE Product Catalog:

42
42 Publications Verification
Cat. No.: HY-P9904
CAS No.: 1380723-44-3
Synonyms: MPDL3280A; RG-7446; RO-5541267

Research Areas:  

Cancer

Atezolizumab (MPDL3280A) is a selective humanized monoclonal IgG1 antibody against programmed death ligand 1 (PD-L1), used for cancer research.
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10
10 Cited Publications
Cat. No.: HY-P73361
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD274; B7 Homolog 1; Prev. PDCD1LG1; B7-H; PD-L1; PDCD1 ligand 1; B7H1; PDCD1L1; PDL1; HPD-L1; Programmed Cell death 1 ligand 1; Programmed death ligand 1; CD274 Antigen; ADMIO5; CD274 Molecule; B7-H1
Species:  
Human
Source:  
HEK293
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4
4 Cited Publications
Cat. No.: HY-N0596
CAS No.: 19666-76-3
Synonyms: 20(R)-Panaxadiol
Panaxadiol (20(R)-Panaxadiol) is an orally active HIF-1α/STAT3 inhibitor. Panaxadiol can suppress HIF-1α and STAT3 then lead to downregulation of programmed cell death-ligand 1 (PD-L1) expression. Panaxadiol shows anticancer, cardioprotective, anti-arrhythmic, and antioxidative activities .
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3
3 Cited Publications
Cat. No.: HY-P99052
CAS No.: 1858168-59-8
Synonyms: BGB-A317
Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology Cancer

Tislelizumab is a monoclonal antibody that specifically binds to programmed cell death receptor 1 (PD-1), blocking its interaction with programmed death ligand 1 (PD-L1) and programmed death ligand 2 (PD-L2). Tislelizumab can reactivate immune cells such as T lymphocytes and enhance anti-tumor activity. Tislelizumab can be used for the research of a variety of tumors including typical Hodgkin's lymphoma, urothelial carcinoma, non-small cell lung cancer and hepatocellular carcinoma .
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3
3 Cited Publications
Cat. No.: HY-P70632
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD274; B7 Homolog 1; Prev. PDCD1LG1; B7-H; PD-L1; PDCD1 ligand 1; B7H1; PDCD1L1; PDL1; HPD-L1; Programmed Cell death 1 ligand 1; Programmed death ligand 1; CD274 Antigen; ADMIO5; CD274 Molecule; B7-H1
Species:  
Mouse
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P84982
Synonyms: Programmed cell death 1 ligand 1; PD-L1; PDCD1 ligand 1; Programmed death ligand 1; B7 homolog 1; B7-H1; CD antigen CD274; CD274 nanobody; PD-L1 nanobody;

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

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1
1 Cited Publications
Cat. No.: HY-P7397
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD274; B7 Homolog 1; Prev. PDCD1LG1; B7-H; PD-L1; PDCD1 ligand 1; B7H1; PDCD1L1; PDL1; HPD-L1; Programmed Cell death 1 ligand 1; Programmed death ligand 1; CD274 Antigen; ADMIO5; CD274 Molecule; B7-H1
Species:  
Human
Source:  
CHO
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Cat. No.: HY-138139A
CAS No.: 2490497-93-1
Purity:  99.46%
Synonyms: T785 hydrochloride
Research Areas:  

Inflammation/Immunology Cancer

AXC-715 (T785) hydrochloride is a TLR7/TLR8 dual agonist. AXC-715 can be used for synthesis of antibody-adjuvant immunoconjugates, comprising an antibody construct that binds programmed death-ligand 1 (PD-L1) linked to one or more adjuvants .
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Cat. No.: HY-P10439
CAS No.: 2349354-64-7
Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology Cancer

CVRARTR is a programmed cell death ligand-1 (PD-L1) antagonist with a KD of 281 nM. CVRARTR induces the internalization of PD-L1 and downregulates PD-L1 on the cell surface. CVRARTR restores cytokine secretion and T cell proliferation in cell CT26. CVRARTR exhibits antitumor efficacy against in CT26 homograft mouse model. CVRARTR can be used in melanoma research .
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Cat. No.: HY-P99114
CAS No.: 2256084-03-2

Target:  

PD-1/PD-L1

Research Areas:  

Cancer

Sugemalimab is a fully human, full length, anti-programmed death ligand 1 (PD-L1) immunoglobulin G4 (IgG4) monoclonal antibody (mAb). Sugemalimab shows anticancer activities and can be used for non-small cell lung cancer research .
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Cat. No.: HY-P3440
CAS No.: 1886057-64-2
Research Areas:  

Cancer

WL12 is a specifically targeting programmed death ligand 1 (PD-L1) binding peptide. WL12 can be radiolabeled by different radionuclides, generating radiotracers, which can assess the tumor PD-L1 expression .
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Cat. No.: HY-128605
CAS No.: 2349372-98-9
Purity:  98.99%
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor with an IC50 of 92.3 nM .
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Cat. No.: HY-138139B
CAS No.: 2479276-17-8
Purity:  99.76%
Synonyms: T785 trihydrochloride
Research Areas:  

Inflammation/Immunology Cancer

AXC-715 (T785) trihydrochloride is a TLR7/TLR8 dual agonist. AXC-715 trihydrochloride can be used for synthesis of antibody-adjuvant immunoconjugates, comprising an antibody construct that binds programmed death-ligand 1 (PD-L1) linked to one or more adjuvants .
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Cat. No.: HY-P10950
CAS No.: 1931111-41-9
Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology Cancer

PD-L1 inhibitory peptide is an inhibitor peptide targeting programmed cell death ligand 1 (PD-L1). PD-L1 inhibitory peptide binds to PD-L1, relieving immunosuppression and restoring the antitumor activity of T cells. PD-L1 inhibitory peptide is promising for research of cancers .
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Cat. No.: HY-175323
Target:  

Integrin PD-1/PD-L1

Research Areas:  

Cancer

NOTA-IMB-RGD is a dual molecular probe targeting integrin αvβ3 and programmed death ligand-1 (PD-L1). NOTA-IMB-RGD blocks the PD-1/PD-L1 signaling pathway and integrin αvβ3-overexpressing tumor vasculature. NOTA-IMB-RGD is promising for research of solid tumors co-expressing PD-L1 and αvβ3 (e.g., glioma, breast cancer) .
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Cat. No.: HY-P990757
CAS No.: 2763222-58-6
Synonyms: ABL503, TJ-L14B

Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology

Ragistomig can simultaneously target programmed death-ligand 1 (PD-L1) and the 4-1BB receptor. Ragistomig elicits potent anti-tumor T-cell responses without inducing significant toxicity. Ragistomig is applicable for tumor research .
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Cat. No.: HY-151066
CAS No.: 2447065-99-6
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

BMS-1233 is an orally active inhibitor for programmed cell death-ligand 1 (PD-L1), with IC50 of 14.5 nM. BMS-1233 promotes cell death of HepG2 in a Jurkat T cell and HepG2 cell co-culture model, exhibits antitumor activity against melanoma in mouse model .
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Cat. No.: HY-P991151
CAS No.: 2923499-76-5
Synonyms: LBL-024
Target:  

PD-1/PD-L1 TNF Receptor

Research Areas:  

Cancer

Opamtistomig is a humanized immunoglobulin (H-γ1-scFv-L-κ) dimer monoclonal antibody targeting human programmed death ligand 1 (PD-L1), CD274 and tumor necrosis factor receptor superfamily member 9 (TNFRSF9). Opamtistomig is promising for research of various solid tumors and hematological malignancies .
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Cat. No.: HY-158052
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

PD-1/PD-L1 antagonist 1 (Compound A5) is an antagonist for programmed cell death-1 (PD-1) and programmed cell death ligand-1 (PD-L1) interaction, with an IC50 of 23.78 nM .
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Cat. No.: HY-N0596R
CAS No.: 19666-76-3
Synonyms: 20(R)-Panaxadiol (Standard)
Panaxadiol (Standard) is the analytical standard of Panaxadiol. This product is intended for research and analytical applications. Panaxadiol (20(R)-Panaxadiol) is an orally active HIF-1α/STAT3 inhibitor. Panaxadiol can suppress HIF-1α and STAT3 then lead to downregulation of programmed cell death-ligand 1 (PD-L1) expression. Panaxadiol shows anticancer, cardioprotective, anti-arrhythmic, and antioxidative activities .
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