2 Results for "

RA-FLS cell

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "RA-FLS cell" in MCE Product Catalog:

Cat. No.: HY-W668749
CAS No.: 2374782-82-6
Target:  

FAP

Research Areas:  

Inflammation/Immunology

3BP-3580 (compound 11) is a conjugate targeting FAP that binds to FAP-positive cells via the FAPI moiety and internalizes, delivering the payload to FAP-expressing cells, thereby inhibiting RA FLS proliferation, migration, and invasion, reducing inflammatory cytokine expression, and suppressing pannus formation. 3BP-3580 can be used for research on rheumatoid arthritis .
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Cat. No.: HY-N11957
CAS No.: 77165-80-1
Angeloylbinankadsurin A (compound 7) is an anti-rheumatoid arthritis (RA) agent that can be isolated from EtOAc and CH2Cl2 extracts of Black Tiger Beard. Angeloylbinankadsurin A exhibits inhibitory activity on RA-FLS cells (IC50=11.70 μM). Angeloylbinankadsurin A is slightly toxic to human cancer cell lines (Hela and BGC-823) (IC50=19.9 μM, 21.93 μM) .
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