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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
REM
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "REM" in MCE Product Catalog:
Cat. No.: HY-162566
CAS No.: 1417823-67-6
Research Areas:
REM127 is an orally active, blood-brain barrier-penetrant septin 6/7 molecular glue degrader. REM127 binds to SEPT6 with high affinity and promotes the assembly of SEPT2/6/7 cortical filaments, thereby normalizing cytoplasmic calcium levels, cerebrospinal fluid hyperphosphorylated tau protein levels, synaptic function and cognitive function. REM127 can be used in research related to Alzheimer's disease .
Cat. No.: HY-RS19637
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Rem1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Rem1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS11837
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REM1 Human Pre-designed siRNA Set A contains three designed siRNAs for REM1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS11838
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REM2 Human Pre-designed siRNA Set A contains three designed siRNAs for REM2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24105
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Rem2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Rem2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26131
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Rem1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Rem1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-168365
CAS No.: 26126-01-2
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(±)-Pellotine hydrochloride (Compound 2) is an alkaloid, which is found in L. diffusa and L. fricii. (±)-Pellotine hydrochloride decreases locomotor activity and the amount of rapid eye movement (REM) sleep in mice .
Cat. No.: HY-RS17645
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Rem2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Rem2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-150192
CAS No.: 21489-20-3
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Talsupram is a selective noradrenaline inhibitor that has a high affinity for the noradrenaline transporter. Talsupram exhibits anti-hyperalgesic effects. Talsupram can decrease ethanol intake to the levels prior to REM-induced deprivation in rat model .
Cat. No.: HY-124492
CAS No.: 21489-22-5
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Prindamine is a noradrenaline transporter inhibitor with very weak anticholinergic and serotonin (5-HT) uptake inhibiting effects. Prindamine blocks noradrenaline uptake, increasing synaptic availability of noradrenaline in the brain. Prindamine decreases rapid eye movement sleep (REMS) in cats. Prindamine initially increases the proportion of time spent in active wakefulness in cats .
Cat. No.: HY-184060
CAS No.: 1704716-36-8
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ASP8062 is an orally active, blood-brain barrier-permeable selective GABAB receptor positive allosteric modulator. ASP8062 enhances GABA-mediated activation of GABAB receptors and strengthens GABAergic neurotransmission. ASP8062 reverses Reserpine (HY-N0480)-induced myalgia, regulates the sleep-wake cycle, increases delta wave power during non-REM sleep, and impairs motor coordination at high doses. ASP8062 penetrates the central nervous system with a half-life of 40-50 h. ASP8062 can be used in research related to opioid use disorder, fibromyalgia, chronic pain, and alcohol use disorder .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
