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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
Rab10
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "Rab10" in MCE Product Catalog:
Cat. No.: HY-RS11514
Target:
Research Areas:
RAB10 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS21710
Target:
Research Areas:
Rab10 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Rab10 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS28228
Target:
Research Areas:
Rab10 Rat Pre-designed siRNA Set A contains three designed siRNAs for Rab10 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P703647
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Rab10; Ras-Related Protein Rab-10; Rab10, Member RAS Oncogene Family; GTP-Binding Protein Rab10; Ras-Related GTP-Binding Protein; Small Monomeric GTPase
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P706189
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Ras-related protein Rab-10; EC:3.6.5.2; Rab10
Species:
Human
Source:
P. pastoris
Cat. No.: HY-184198
CAS No.: 1427947-55-4
Target:
Research Areas:
LRRK2-IN-22 is a LRRK2 inhibitor, with IC50 values of 315.7 nM and 255.4 nM against LRRK2 WT and LRRK2 G2019S, respectively. LRRK2-IN-22 effectively inhibits LRRK2 kinase activity and downstream Rab10 phosphorylation, reduces ROS, and exhibits low cytotoxicity. LRRK2-IN-22 can be used for research on Parkinson's disease .
Cat. No.: HY-180320
CAS No.: 1632368-13-8
Target:
Research Areas:
Lu AF58786 is a potent and selective LRRK2 inhibitor with an IC50 of 12 nM. Lu AF58786 also exhibits inhibition activity against LRRK2 G2019S and LRRK2 A2016T with IC50s of 19 and 93 nM. Lu AF58786 inhibits phosphorylation of LRRK2, Rab10 and Rab12 in human peripheral blood mononuclear cells. Lu AF58786 can be used for parkinson’s disease research .
Cat. No.: HY-189065
CAS No.: 2765654-79-1
Target:
Research Areas:
STF-3600 is a LRRK2 G2019S inhibitor with an IC50 of 0.9 nM against the human target. It has oral activity and can cross the blood-brain barrier. STF-3600 selectively inhibits kinase activity, including autophosphorylation at Ser935 and Ser1292, as well as phosphorylation of the endogenous substrate Rab10 at Thr73. STF-3600 inhibits vacuolization of type II pulmonary epithelial cells in wild-type/heterozygous mice, while it induces this vacuolization phenotype in homozygous mice. STF-3600 can be used in Parkinson's disease research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
