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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
RbAp48
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "RbAp48" in MCE Product Catalog:
Cat. No.: HY-174372
CAS No.: 3095068-20-2
Target:
Research Areas:
EZH2-IN-23 (Compound 25) is an EZH2 inhibitor that exhibits potent enzymatic inhibition of the PRC2 complex (EZH2, EED, SUZ12, AEBP2, RbAp48) with a biochemical IC50 of 0.8 nM. EZH2-IN-23 inhibits H3K27 trimethylation in cellular assays, showing an IC50 of 40 nM. EZH2-IN-23 displays good rat PKproperties with 100 % oral bioavailability.
Cat. No.: HY-168131
CAS No.: 3098718-46-5
Research Areas:
PROTAC EZH2 Degrader-3 is a EZH2 PROTAC degrader. PROTAC EZH2 Degrader-3 induces the global degradation of the PRC2 complex (including EZH2, SUZ12, EED, RbAp48) via the ubiquitin-proteasome pathway and downregulates H3K27me3 levels. PROTAC EZH2 Degrader-3 inhibits cancer cell proliferation and induces their apoptosis. PROTAC EZH2 Degrader-3 can be used in research related to lymphoblastoma and diffuse large B-cell lymphoma .
Cat. No.: HY-181320
CAS No.: 2653338-65-7
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Research Areas:
PROTAC EZH2 Degrader-19 (compound 6) is a is a PROTAC protein degrader targeting EZH2 with an IC50 of 15.00 nM. PROTAC EZH2 Degrader-19 induces strong degradation of all PRC2 subunits (EZH2, SUZ12, EED, RbAp48) in a concentration- and time-dependent manner.PROTAC EZH2 Degrader-19 exhibits antiproliferative effects in cancer cells.PROTAC EZH2 Degrader-19 can be used for the research of cancer .
Cat. No.: HY-P74601
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Histone-binding protein RBBP4; CAF-I p48; RBBP-4; RbAp48
Species:
Source:
Cat. No.: HY-P74600
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Histone-binding protein RBBP4; CAF-I p48; RBBP-4; RbAp48
Species:
Source:
Cat. No.: HY-RS11716
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Research Areas:
RBBP4 Human Pre-designed siRNA Set A contains three designed siRNAs for RBBP4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18187
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Research Areas:
Rbbp4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Rbbp4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-181308
CAS No.: 2653338-63-5
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Research Areas:
PROTAC EZH2 Degrader-13 is an EZH2-targeting PROTAC with an IC50 of 2.70 nM. PROTAC EZH2 Degrader-13 exerts antiproliferative effects in cancer cells. PROTAC EZH2 Degrader-13 can be used for the research of cancer .
Cat. No.: HY-181323
CAS No.: 2653338-66-8
Target:
Research Areas:
PROTAC EZH2 Degrader-22 (compound 7) is a PROTAC protein degrader targeting EZH2. PROTAC EZH2 Degrader-22 is applicable to cancer-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
