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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
33 Results for "
S16
" in MedChemExpress (MCE) Product Catalog:
Products (33)
33 Results for "S16" in MCE Product Catalog:
20
20 Cited Publications
Synonyms: ITMN-191; R7227; RO5190591; RG7227
Target:
Research Areas:
Danoprevir (ITMN-191) is an orally active NS3/4A protease inhibitor for hepatitis C virus (HCV) with an IC50 of 0.29 nM and is selective for NS3/4A over a panel of 53 proteases (IC50 higher than 10 μM). Danoprevir (ITMN-191) inhibits HCV genotypes 1a, 1b, 4, 5, and 6 (IC50s=0.2-0.4 nM) as well as 2b and 3a (IC50s=1.6, 3.5 nM) . Danoprevir is also a SARS-CoV 3CL pro inhibitor with an IC50 of 0.05 μM .
Cat. No.: HY-B0389S16
CAS No.: 40762-22-9
Synonyms: Glucose-1-13C; D-(+)-Glucose-1-13C; Dextrose-1-13C
Cat. No.: HY-N0210S16
CAS No.: 74134-89-7
Synonyms: D-(+)-Galactose-13C6
Cat. No.: HY-B0400S16
CAS No.: 121067-66-1
Synonyms: Sorbitol-13C6; D-Glucitol-13C6
Cat. No.: HY-N0229S16
CAS No.: 19470-97-4
Synonyms: L-2-Aminopropionic acid-d3-1
Cat. No.: HY-N0473S16
CAS No.: 2483830-06-2
Cat. No.: HY-N0830S16
CAS No.: 83293-32-7
Cat. No.: HY-N7092S16
CAS No.: 285979-75-1
Synonyms: D(-)-Fructose-d2
Cat. No.: HY-W018772S16
CAS No.: 209909-88-6
Target:
Research Areas:
D-Ribose-1,2- 13C2 is the 13C labled D-Ribose(mixture of isomers) (HY-W018772) . D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner .
Cat. No.: HY-N0215S16
CAS No.: 136056-01-4
Synonyms: (S)-2-Amino-3-phenylpropionic acid-13C-1
Target:
Research Areas:
CC-3060 is a molecular glue modulator targeting Cereblon (CRBN) E3 ubiquitin ligase and ZBTB16 degrader with a DC50 of 0.47 nM in HT-1080 cells. CC-3060 engages structural degrons on ZBTB16’s ZnF1 or ZnF3 domains for fusion protein substrates. CC-3060 can be used for the research of acute promyelocytic leukemia .
Cat. No.: HY-161043
Target:
Research Areas:
ECDD-S16 is a potent inhibitor of pyroptosis. ECDD-S16 inhibits surface and endosomal TLR ligands activated pyroptosis in Raw264.7 cells .
Cat. No.: HY-161331
CAS No.: 2653349-51-8
Target:
Research Areas:
S16–1029 is a selective and orally active butyrylcholinesterase (BChE) inhibitor with IC50s of 11.35 nM and 48.1 nM for eqBChE and hBChE, respectively. S16–1029 could cross the blood-brain barrier (BBB) and reach the central nervous system (CNS). S16–1029 can be used for Alzheimer's disease (AD) research .
Cat. No.: HY-Z1917S
CAS No.: 1217617-88-3
Cat. No.: HY-179008A
CAS No.: 2841458-00-0
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Research Areas:
(S)-5-HT2CR agonist 1 (Compound (S)-16k) is selective 5-HT2CR agonist, with an EC50 of 14 nM. FXa-IN-2 can be used in the research of hyperlocomotion .
Cat. No.: HY-N8664
CAS No.: 213905-35-2
Target:
Cat. No.: HY-N11496
CAS No.: 2569209-22-7
Category:
Terpenoids Bituminaria morisiana (Pignatti & Metlesics) Greuter Diterpenoids Plants Compositae Extract
Target:
Cat. No.: HY-RS12227
Target:
Research Areas:
RPS16 Human Pre-designed siRNA Set A contains three designed siRNAs for RPS16 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-181499
CAS No.: 3132225-37-4
Target:
Research Areas:
RA190-PEG1-NH2 (Compound S16) is a derivative of RA190 (HY-100739) and acts as a Proteasome ligand. RA190-PEG1-NH2 can be used for the synthesis of the FKBP12 PROTAC degrader RAFKBP12 (HY-181498) .
Cat. No.: HY-161820
CAS No.: 3049492-11-4
Target:
Research Areas:
IAV-IN-3 (Compound (R,S)-16s) is an anti-influenza A virus (IAV) agent (EC50 = 0.134 μM) with weak cytotoxicity (CC50 = 15.35 μM for MDCK cells). IAV-IN-3 inhibits IAV polymerase with an IC50 of 0.045 μM .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
