77 Results for "

S228P

" in MedChemExpress (MCE) Product Catalog:
Products (77)

77 Results for "S228P" in MCE Product Catalog:

11
11 Publications Verification
Cat. No.: HY-P99003

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Human IgG4 (S228P) kappa, Isotype Control, a human-derived monoclonal antibody, is an isotype control for human IgG4κ antibody.
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-P99176

Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

ATG-031 is a humanized anti-CD24 monoclonal antibody with high affinity and specificity. ATG-031 interacts with Siglec-10 expressed by tumor-associated macrophages. ATG-031 effectively stimulates macrophage-mediated phagocytosis and induces cancer cell destruction by blocking the anti-phagocytic surface proteins. ATG-031 can be used in the study of haematological malignancies as well as solid tumors. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P99100
CAS No.: 2556646-63-8
Synonyms: CTL-002

Research Areas:  

Cancer

Visugromab (CTL-002) is a GDF-15 neutralizing IgG4 mAb. Visugromab has synergistic anticancer activity with the anti-PD1 antibody Nivolumab (HY-P9903) and can effectively act on PD-1/PD-L1 relapsed/refractory metastatic solid tumors. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P99044
CAS No.: 2252262-24-9
Synonyms: MBG453

Target:  

Tim3

Research Areas:  

Inflammation/Immunology Cancer

Sabatolimab (MBG453) is a high-affinity, humanized, IgG4 (S228P) antibody targeting TIM-3, an inhibitory receptor that regulates adaptive and innate immune responses. Sabatolimab is a potential immunosuppression agent that can target TIM-3 on immune and myeloid cells .
loading...
    loading...
Cat. No.: HY-P99971
CAS No.: 2924764-21-4

Research Areas:  

Cancer

Gemtuzumab is a monoclonal IgG4-κ antibody targeting CD33 antigen. Gemtuzumab affects cell necrosis by specifically targeting CD33 expressed on the surface of leukaemic cell blasts in acute myeloid leukemia (AML). Gemtuzumab can be used for synthesis of antibody-drug conjugate (ADC), Gemtuzumab ozogamicin (HY-109539). Gemtuzumab ozogamicin consists of a cytotoxic derivative of Calicheamicin (a cytotoxic antibiotic), and a monoclonal antibody. Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
loading...
    loading...
Cat. No.: HY-P99987

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Human IgG4 (S228P) lambda1, Isotype Control, a human-derived antibody, is an isotype control for human IgG4 (S228P) λ1 antibody.
loading...
    loading...
Cat. No.: HY-P99613
CAS No.: 2231068-83-8
Synonyms: MK-4280; Mavezelimab

Target:  

LAG-3

Research Areas:  

Cancer

Favezelimab (MK-4280) is a humanized monoclonal antibody targeting LAG-3. Favezelimab blocks the interaction between LAG-3 and its ligand, MHC class II molecules. Favezelimab is applicable to research on relapsed/refractory classical Hodgkin lymphoma, relapsed/refractory diffuse large B-cell lymphoma, and relapsed/refractory indolent B-cell lymphoma . For the isotype control of Favezelimab, refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
loading...
    loading...
Cat. No.: HY-P990091
CAS No.: 2756228-76-7
Synonyms: SAR 445088
Riliprubart (SAR 445088) is a selective anti-C1s humanized IgG4 monoclonal antibody with mutations that enhance its binding to the neonatal Fc receptor. Riliprubart blocks activation of the classical complement pathway, prevents the formation of the C3 convertase C4b2a, and inhibits complement-mediated hemolytic activity. Riliprubart can be used in research related to classical complement-mediated diseases, cold agglutinin disease, and chronic inflammatory demyelinating polyneuropathy. For the isotype control of Riliprubart, refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
loading...
    loading...
Cat. No.: HY-P990319

Target:  

NAMPT

Research Areas:  

Inflammation/Immunology

ALT-100 (Human IgG4) is a humanized antibody expressed in CHO, targeting NAMPT. ALT-100 (Human IgG4) consists of a huIgG1/huIgG4 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. For inflammatory or fibrotic diseases, the isotype control for ALT-100 (Human IgG4) can refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
loading...
    loading...
Cat. No.: HY-P990737
CAS No.: 2484883-56-7
Synonyms: LY-3041658

Target:  

CXCR

Research Areas:  

Inflammation/Immunology

Eltrekibart is an anti-CXCL human IgG4 κ monoclonal antibody . Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
loading...
    loading...
Cat. No.: HY-P990773
CAS No.: 2635407-50-8
Synonyms: LY-3361237

Target:  

CD28

Research Areas:  

Inflammation/Immunology

Venanprubart is an anti-BTLA human IgG4 κ monoclonal antibody . Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
loading...
    loading...
Cat. No.: HY-P990726
CAS No.: 2765071-95-0
Synonyms: KPL-404

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Abiprubart is an anti-CD40 human IgG4 κ monoclonal antibody . Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
loading...
    loading...
Cat. No.: HY-P990743
CAS No.: 2704554-77-6
Synonyms: AB023; Xisomab 3G3; MAB 14E11

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Gruticibart is an anti-F11 human IgG4 κ monoclonal antibody . Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
loading...
    loading...
Cat. No.: HY-P991038
CAS No.: 2904575-77-3

Target:  

CD28

Research Areas:  

Inflammation/Immunology

HY-P991038 is an BTLA-targeting IgG4κ type humanized antibody, the recommed isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
loading...
    loading...
Cat. No.: HY-P990751
CAS No.: 2669823-48-5
Synonyms: HSTC-810

Research Areas:  

Inflammation/Immunology

Nelmastobart is an anti-BTN1A1 human IgG4 κ monoclonal antibody . Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
loading...
    loading...
Cat. No.: HY-P990913
CAS No.: 2765077-69-6
Synonyms: bsAb7075; REGN-7075; Marlotamig

Target:  

EGFR

Research Areas:  

Inflammation/Immunology

HY-P990913 is an EGFR/CD28-targeting IgG4κ type human antibody, the recommed isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
loading...
    loading...
Cat. No.: HY-P990917
CAS No.: 2572467-73-1
Synonyms: ENT-001

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

HY-P990917 is an TMEM219-targeting IgG4λ type human antibody, the recommed isotype control is Human IgG4 (S228P) lambda1, Isotype Control (HY-P99987) .
loading...
    loading...
Cat. No.: HY-P991067
CAS No.: 2724922-85-2
Synonyms: KP-104

Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Vensobafusp alfa (KP-104) is a fusion protein composed of an IgG4 monoclonal antibody directed against terminal complement protein C5 fused to the complement factor H 1-5 domain (FH1-5). Vensobafusp alfa shows anti-inflammatory and immunomodulatory activities. The isotype control for Vensobafusp alfa can refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) . .
loading...
    loading...
Cat. No.: HY-P991057
CAS No.: 2376730-61-7

Target:  

CD47

Research Areas:  

Cancer

STI-6643 is a fully human IgG4 antibody that targets CD47. STI-6643 blocks CD47-SIRPα interaction, and enables macrophage-mediated phagocytosis of tumor cells. STI-6643 shows anti-tumor activity in mouse lymphoma xenograft models. STI-6643 can be used for the research of Burkitt's lymphoma, solid tumors, relapsed or refractory tumors, and lymphoma. The isotype control for STI-6643 can refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
loading...
    loading...
Cat. No.: HY-P990750
CAS No.: 2360418-68-2
Synonyms: IBI-110

Target:  

LAG-3

Research Areas:  

Inflammation/Immunology

Negalstobart is an anti-LAG3 human IgG4 κ monoclonal antibody . Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
loading...
    loading...