Eltrekibart
Based on 1 Customer Validation
Eltrekibart is an anti-CXCL human IgG4 κ monoclonal antibody. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
For research use only. We do not sell to patients.
- Purity : 98.00%
- CAS No.: 2484883-56-7
- Molecular Weight:146.537 kDa
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Storage:Shipping with dry ice
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Isotype
Human IgG4 kappa
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
CXCR1
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | 2011-05 | PHASE1 |
Gene ID
Accession
Conjugated
Unconjugated
Reconstitution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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IgG4-kappa
Application
ELISA, FACS, Functional assay
Verified Bioactivity
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Immobilized GRO-alpha/CXCL1 Protein, Human (HEK293, HY-P70508) can bind Eltrekibart. The ED50 for this effect is 19.68 ng/mL. -
Loaded Eltrekibart on AHC2 biosensor, can bind IL-8/CXCL8 Protein, Human (HY-P7224) with an affinity constant of <1.000E-11 M as determined in BLI assay.
Chemical Information
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CAS No. 2484883-56-7
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Appearance Liquid
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Molecular Weight 146.537 kDa
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Color Colorless to light yellow
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Synonyms
LY-3041658
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (253 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
[1]. Eltrekibart
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)