Negalstobart
Based on 1 Customer Validation
Negalstobart is an anti-LAG3 human IgG4 κ monoclonal antibody. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
For research use only. We do not sell to patients.
- Purity : 96.89%
- CAS No.: 2360418-68-2
- Molecular Weight:144.726 kDa
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Storage:Shipping with dry ice
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Isotype
Human IgG4 kappa
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
LAG3/CD223
Gene ID
Accession
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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IgG4-kappa
Application
ELISA, FACS, Functional assay
Verified Bioactivity
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Immobilized LAG-3 Protein, Human (HEK293, His, HY-P70722) can bind Negalstobart. The EC50 for this effect is 31.27 ng/mL. -
Flow cytometric analysis of 1X106 Jurkat cells labeling LAG3/CD223 with Negalstobart (HY-P990750, red). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa Isotype Control (HY-P99003, blue) was used as the isotype control.
Chemical Information
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CAS No. 2360418-68-2
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Appearance Liquid
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Molecular Weight 144.726 kDa
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Color Colorless to light yellow
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Synonyms
IBI-110
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (255 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
[1]. Negalstobart
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)