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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
38 Results for "
SANK 60501
" in MedChemExpress (MCE) Product Catalog:
Products (38)
38 Results for "SANK 60501" in MCE Product Catalog:
67
67 Publications Verification
Synonyms: GM6001; Galardin
Ilomastat (GM6001) is a potent and broad spectrum matrix metalloprotease (MMP) inhibitor, inhibits MMPs (IC50s, 1.5 nM for MMP-1; 1.1 nM for MMP-2; 1.9 nM for MMP-3; 0.5 nM for MMP-9), with a Ki of 0.4 nM for human skin fibroblast collagenase (MMP-1).
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3 Cited Publications
Synonyms: DS-6051b; AB-106; IBI-344
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Research Areas:
Taletrectinib (DS-6051b) is a potent, orally active, and next-generation selective ROS1/NTRK inhibitor. Taletrectinib potently inhibits recombinant ROS1, NTRK1, NTRK2, and NTRK3 with IC50s of 0.207, 0.622, 2.28, and 0.98 nM, respectively. Taletrectinib also inhibits ROS1 G2032R and other Crizotinib-resistant ROS1 mutants .
1
1 Cited Publications
Synonyms: 5-Hydroxy-1H-imidazole-4-carboxamide; FF-10501
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Bredinin aglycone (5-Hydroxy-1H-imidazole-4-carboxamide) is a purine nucleotide analogue. Bredinin aglycone can be used to examine the efficiency of catalysts for the preparation of purine nucleotide analogues .
Cat. No.: HY-P99191
CAS No.: 1709815-23-5
Synonyms: NI-0501
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Cat. No.: HY-19929
CAS No.: 1239278-59-1
Synonyms: CHF-6001
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Tanimilast (CHF-6001) is an orally active and selective phosphodiesterase 4 inhibitor (IC50=0.026 nM) with robust anti-inflammatory activity and suitable for topical pulmonary administration. Tanimilast increases cellular cAMP levels, and inhibits NF-κB signaling pathway. Tanimilast is used for the research of obstructive lung diseases .
Cat. No.: HY-P990040
CAS No.: 2642171-64-8
Synonyms: LVGN-6051
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Cat. No.: HY-P9994
CAS No.: 2500674-05-3
Synonyms: SBT6050
Research Areas:
Synonyms: (8S)-8-Fluoroerythromycin A; P-0501A
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Flurithromycin ((8S)-8-Fluoroerythromycin A) is an orally active broad spectrum antibiotic. Flurithromycin can be used in the research of bacterial infections .
Cat. No.: HY-131003A
CAS No.: 1505514-27-1
Synonyms: DS-6051b free base; AB-106 free base; IBI-344 free base
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Taletrectinib (DS-6051b) free base is a potent, orally active, and next-generation selective ROS1/NTRK inhibitor. Taletrectinib free base potently inhibits recombinant ROS1, NTRK1, NTRK2, and NTRK3 with IC50s of 0.207, 0.622, 2.28, and 0.98 nM, respectively. Taletrectinib free base also inhibits ROS1 G2032R and other Crizotinib-resistant ROS1 mutants .
Cat. No.: HY-P991566
CAS No.: 2983061-18-1
Cat. No.: HY-15768R
CAS No.: 142880-36-2
Synonyms: GM6001 (Standard); Galardin (Standard)
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Ilomastat (Standard) is the analytical standard of Ilomastat. This product is intended for research and analytical applications. Ilomastat (GM6001) is a potent and broad spectrum matrix metalloprotease (MMP) inhibitor, inhibits MMPs (IC50s, 1.5 nM for MMP-1; 1.1 nM for MMP-2; 1.9 nM for MMP-3; 0.5 nM for MMP-9), with a Ki of 0.4 nM for human skin fibroblast collagenase (MMP-1).
Cat. No.: HY-106138
CAS No.: 140703-49-7
Synonyms: Meterelin; MF 6001
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Cat. No.: HY-101643
CAS No.: 117705-18-7
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RP-60503 is an orally active anxiolytic cyclopyrrolone derivative with low sedative potential. RP-60503 binds to the gamma-aminobutyric acidA (GABA)/benzodiazepine receptor with a Ki value of 1.16 nM. RP-60503 can be used for the research of neurological disease .
Cat. No.: HY-19929A
Synonyms: (R)-CHF-6001
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(R)-Tanimilast is a isomeride of Tanimilast (HY-19929). Tanimilast (CHF-6001) is a novel highly potent and selective phosphodiesterase 4 inhibitor (IC50=0.026 nM) .
Cat. No.: HY-RI01930
hsa-miR-6501-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
Cat. No.: HY-106048R
CAS No.: 56973-26-3
Synonyms: 5-Hydroxy-1H-imidazole-4-carboxamide (Standard); FF-10501 (Standard)
Cat. No.: HY-W182790
CAS No.: 150985-54-9
Synonyms: LSL 60101
Garsevil (LSL 60101) is a biphasic, selective imidazoline I2 receptor (I2-IR) ligand, with a pKi of 9.03 and a Ki of 0.9 nM at the high-affinity site, and a pKi of 5.25 and a Ki of 5.6 nM at the low-affinity site. Garsevil is applicable to research related to Alzheimer's disease .
Cat. No.: HY-189002
CAS No.: 866554-59-8
Synonyms: ZHD 0501
ACT-007 (ZHD 0501) is an indolocarbazole alkaloid derived from Actinomadura sp., which selectively inhibits the proliferation of lung cancer cells and induces G2/M phase cell cycle arrest in breast cancer cells. ACT-007 can be applied in the research of lung cancer and breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
