7 Results for "

SEMA4A

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "SEMA4A" in MCE Product Catalog:

Cat. No.: HY-RS12657
Research Areas:  

Others

SEMA4A Human Pre-designed siRNA Set A contains three designed siRNAs for SEMA4A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS18312
Research Areas:  

Others

Sema4a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sema4a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS24790
Research Areas:  

Others

Sema4a Rat Pre-designed siRNA Set A contains three designed siRNAs for Sema4a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P71283
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SEMAphorin-4A; SEMAphorin-B; SEMA B; SEMA4A; SEMAb; SemB
Species:  
Source:  
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Cat. No.: HY-P76056
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SEMAphorin-4A; SEMAphorin-B; SEMA B; SEMA4A; SEMAb; SemB
Species:  
Source:  
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Cat. No.: HY-P76055
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SEMAphorin-4A; SEMAphorin-B; SEMA B; SEMA4A; SEMAb; SemB
Species:  
Source:  
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Cat. No.: HY-P992388

Target:  

LILRB

Research Areas:  

Cancer

IO-108 is a humanized IgG4 monoclonal antibody and a competitive inhibitor of LILRB2, with a KD value of 1.97 nM. IO-108 competitively blocks the binding of LILRB2 to its ligands including HLA-G, MHC-I, ANGPTL2 and SEMA4A, reprograms tumor-associated myeloid cells, drives the conversion of suppressive myeloid cells into a pro-inflammatory phenotype, and restores the cytotoxic activity of T cells and NK cells. IO-108 inhibits tumor growth in LILRB2 transgenic mouse models. IO-108 can be used for the research of solid tumors .
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