2 Results for "

SFTSV glycoprotein Gn

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "SFTSV glycoprotein Gn" in MCE Product Catalog:

Pronaphthalide A
Pronaphthalide A
0 Images
Cat. No.: HY-N21711
CAS No.: 1624617-93-1
Category:  

Acanthaceae Extract Conioselinum smithii (H. Wolff) Pimenov & Kljuykov Lignans Phenylpropanoids Plants

Target:  

Biochemical Assay Reagents

Pronaphthalide A is a cytotoxic agent and an inhibitor of SFTSV glycoprotein Gn (domain B) (Kd = 0.74 mM). It blocks viral binding and internalization by binding to the conserved B domain of SFTSV Gn, thereby inhibiting SFTSV infection at the viral entry stage, and exhibits broad-spectrum antiviral activity against bunyaviruses. Pronaphthalide A can be used for research on gastric cancer, severe fever with thrombocytopenia syndrome, and HIV/AIDS .
loading...
    loading...
View All Sizes
Procumbenoside I
Procumbenoside I
0 Images
Cat. No.: HY-N21657
CAS No.: 2243471-10-3
Category:  

Acanthaceae Extract Conioselinum smithii (H. Wolff) Pimenov & Kljuykov Lignans Phenylpropanoids Plants

Target:  

VSV SARS-CoV Influenza Virus Arenavirus

Procumbenoside I is a naturally derived broad-spectrum antiviral agent targeting the SFTSV glycoprotein Gn. Procumbenoside I binds to the conserved B domain of SFTSV Gn, blocking the binding and internalization steps during viral entry. Procumbenoside I inhibits the entry of VSV, H5N1, and SARS-CoV-2 pseudoviral particles, while exhibiting antiviral activity against bunyaviruses such as LCMV and WELV. Procumbenoside I protects mice against lethal SFTSV challenge, reducing mortality and alleviating pathological damage. Procumbenoside I is useful for research related to viral infections .
loading...
    loading...
View All Sizes
Assay Types