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Results for "

SNAIL/SLUG

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Biochemical Assay Reagents

2

Natural
Products

4

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1647
    Ferric phosphate

    		Insecticide Others
    Ferric phosphate is used as food and feed supplement, particularly in bread enrichment. Ferric phosphate is also used as a fertilizer and as a molluscicide for a variety of slugs and snails including Deroceras reticulatum, D.laeve, Arion subfuscus .
    Ferric phosphate
  • HY-157435
    PELI1-IN-1

    		E1/E2/E3 Enzyme Cytochrome P450 Proteasome Cancer
    PELI1-IN-1 (compound 3d) is a potent inhibitor of PELI1, E3 ubiquitin ligase. PELI1-IN-1 has anti-tumPELI1-IN-1, a Resveratrol (HY-16561) derivative, is an orally active PELI1 Inhibitor (Kd = 8.2 μM). PELI1-IN-1 markedly interrupts the interaction of PELI1 and SNAIL/SLUG, and inhibits the K63-polyubiquitization of SNAIL/SLUG by PELI1, subsequently downregulating the protein levels of epithelial-mesenchymal transition (EMT) effectors SNAIL/SLUG. PELI1-IN-1 significantly reduces the level of SNAIL, SLUG and Vimentin without affecting the PELI1 expression. PELI1-IN-1 targets the FHA domain of PELI1 and disrupts the interaction, leading to the anti-metastasis of TNBC cells in vitro and in vivo. PELI1-IN-1 shows no evident toxicity in vivo .
    PELI1-IN-1
  • HY-B1870
    Metaldehyde

    		Environmental Pollutants Insecticide Infection
    Metaldehyde is a commonly used pesticide for mollusks such as slugs and snails.
    Metaldehyde
  • HY-N10449
    Resistomycin

    		Antibiotic Apoptosis Bacterial Cancer
    Resistomycin, a pentacyclic polyketide antibiotic, possesses anticancer activity and induces apoptosis .
    Resistomycin
  • HY-N15267
    Ovalitenone

    		FAK Akt mTOR Cancer
    Ovalitenone is a flavonoid compound that can be isolated from the plant Millettia peguensis. It shows no cytotoxic effects on lung cancer H460 and A549 cells, but it significantly inhibits anchorage-independent growth, CSC-like phenotypes, colony formation, and the migration and invasion capabilities of cancer cells. Ovalitenone can significantly reduce the levels of N-cadherin, snail, and slug, while increasing E-cadherin, thus inhibiting the EMT pathway. Additionally, Ovalitenone suppresses the signaling pathways regulated by focal adhesion kinase (FAK), ATP-dependent tyrosine kinase (AKT), mammalian target of rapamycin (mTOR), and cell division cycle 42 (Cdc42) .
    Ovalitenone
  • HY-B1870R
    Metaldehyde (Standard)

    		Insecticide Reference Standards Infection
    Metaldehyde (Standard) is the analytical standard of Metaldehyde. This product is intended for research and analytical applications. Metaldehyde is a commonly used pesticide for mollusks such as slugs and snails.
    Metaldehyde (Standard)

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