11 Results for "

SRE

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "SRE" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-137862
CAS No.: 65528-98-5
Purity:  99.90%
Synonyms: 1-Oleoyl-sn-glycero-3-phosphate; 1-Oleoyl-LPA
Target:  

LPL Receptor

Research Areas:  

Neurological Disease

1-Oleoyl lysophosphatidic acid (1-Oleoyl-sn-glycero-3-phosphate) is an abundant lysophosphatidic acid (LPA) species with high biological activity due to its strong affinity for the LPA receptors. 1-Oleoyl lysophosphatidic acid is commonly used in most laboratories as a reagent for LPA receptor activation . 1-Oleoyl lysophosphatidic acid increases SRE-driven β-galactosidase activity .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-108361
CAS No.: 1443437-74-8
Purity:  99.89%
Target:  

Ras

Research Areas:  

Inflammation/Immunology Cancer

CCG-203971 is a second-generation Rho/MRTF/SRF pathway inhibitor. CCG-203971 potently targets RhoA/C-activated SRE-luciferase (IC50 =6.4 μM). CCG-203971 inhibits PC-3 cell migration with an IC50 of 4.2 μM. Potential anti-metastasis Agent .
loading...
    loading...
Cat. No.: HY-10957
CAS No.: 145455-23-8
Purity:  99.90%
Synonyms: MK-0751
Target:  

GHSR

Research Areas:  

Metabolic Disease

L-692429 (MK-0751) is a benzolactam derivative and a nonpeptidyl growth hormone secretagogue (GHS) agonist. L-692429 binds to G protein-coupled receptor with a Ki of 63 nM .
loading...
    loading...
Cat. No.: HY-P10256A
Research Areas:  

Endocrinology

Kiss2 peptide acetate is the acetate form of Kiss2 pepride (HY-P10256). Kiss2 peptide acetate is a positive regulator of reproduction. Kiss2 peptide acetate binds with its cognate receptor Kiss2R (GPR54) in COS-7 cells, activates PKA and PKC signaling pathways through Gas and Gaq proteins, and thus enhances the activity of cAMP response element-dependent luciferase (CRE-luc) and serum response element-dependent luciferase (SRE-luc) .
loading...
    loading...
Cat. No.: HY-155070
Research Areas:  

Cancer

SRE-II, an amide derivative, is an activatable photosensitizer for photodynamic cancer research with decreased fluorescence and photosensitizing capabilities. SRE-II can be further converted into the active photosensitizer SDU Red via carboxylesterase-catalyzed amide bond cleavage. SRE-II induces DNA damage and cell apoptosis in the presence of light. SRE-II can act as a promising theranostic agent for triple-negative breast cancer .
loading...
    loading...
Cat. No.: HY-158652
CAS No.: 2309931-09-5
Target:  

Ras Akt PI3K

Research Areas:  

Cancer

(R)-CCG-1423 is an inhibitor of RhoA. (R)-CCG-1423 inhibits downstream of Rho and shows specificity for SRE .
loading...
    loading...
Cat. No.: HY-136942
CAS No.: 372497-52-4
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

DS1 is a potent GABAA agonist. DS1 increases the activity of serum response element (SRE) and cAMP response element (CRE) promoters. DS1 induces luteinizing hormone beta (LHbeta) and follicle-stimulating hormone beta (FSHbeta) promoter activity .
loading...
    loading...
Cat. No.: HY-P10256
CAS No.: 1111070-93-9
Research Areas:  

Endocrinology

Kiss2 peptide is a positive regulator of reproduction. Kiss2 peptide binds with its cognate receptor Kiss2R (GPR54) in COS-7 cells, activates PKA and PKC signaling pathways through Gas and Gaq proteins, and thus enhances the activity of cAMP response element-dependent luciferase (CRE-luc) and serum response element-dependent luciferase (SRE-luc) .
loading...
    loading...
Cat. No.: HY-10957A
CAS No.: 169188-19-6
Synonyms: MK-0751 hydrochloride
Target:  

GHSR

Research Areas:  

Metabolic Disease

L-692429 (MK-0751) hydrochloride is a benzolactam derivative and a nonpeptidyl growth hormone secretagogue (GHS) agonist. L-692429 hydrochloride binds to G protein-coupled receptor with a Ki of 63 nM .
loading...
    loading...
Cat. No.: HY-108361R
CAS No.: 1443437-74-8
Target:  

Reference Standards Ras

Research Areas:  

Inflammation/Immunology Cancer

CCG-203971 (Standard) is the analytical standard of CCG-203971 (HY-108361). This product is intended for research and analytical applications. CCG-203971 is a second-generation Rho/MRTF/SRF pathway inhibitor. CCG-203971 potently targets RhoA/C-activated SRE-luciferase (IC50 =6.4 μM). CCG-203971 inhibits PC-3 cell migration with an IC50 of 4.2 μM. Potential anti-metastasis Agent .
loading...
    loading...
Cat. No.: HY-180419
CAS No.: 1883721-73-0
Target:  

ERK Apoptosis c-Myc

Research Areas:  

Inflammation/Immunology Cancer

SF-3-030 is a potent, selective and non-ATP competitive ERK1/2 inhibitor. SF-3-030 selectively induces apoptosis in melanoma cells containing mutated BRaf and constitutively active ERK1/2 signalling. SF-3-030 mitigates multiple features of asthma in a murine model of asthma. SF-3-030 can be used for the research of asthma and melanomasup .
loading...
    loading...
  • 1