(R)-CCG-1423
Based on 14 publication(s) in Google Scholar
(R)-CCG-1423 is an inhibitor of RhoA. (R)-CCG-1423 inhibits downstream of Rho and shows specificity for SRE.
For research use only. We do not sell to patients.
- CAS No.: 2309931-09-5
- Formula: C18H13ClF6N2O3
- Molecular Weight:454.75
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) (R)-CCG-1423
More- Exp Mol Med. 2023 May;55(5):898-909. [Abstract]
- Redox Biol. 2026 Mar:90:104049. [Abstract]
- Cell Rep. 2025 Jun 10;44(6):115842. [Abstract]
- Cell Rep. 2025 Mar 5;44(3):115397. [Abstract]
- Clin Transl Med. 2022 Jun;12(6):e850. [Abstract]
- Cell Biosci. 2021 Jan 28;11(1):25. [Abstract]
- Life Sci. 2024 Aug 31:123036. [Abstract]
- Commun Biol. 2021 Mar 25;4(1):399. [Abstract]
- Cancers (Basel). 2020 Nov 27;12(12):3540. [Abstract]
- Tissue Eng Part A. 2023 Aug;29(15-16):424-438. [Abstract]
- Theriogenology. 2019 Oct 15:138:84-93. [Abstract]
- Arch Dermatol Res. 2024 Jun 14;316(7):385. [Abstract]
- Reprod Fertil Dev. 2020 Mar;32(5):522-530. [Abstract]
- bioRxiv. 2024 Dec 5:2024.12.04.626665. [Abstract]
Biological Activity
Chemical Information
-
CAS No. 2309931-09-5
-
Molecular Weight 454.75
-
Formula C18H13ClF6N2O3
-
SMILES
ClC(C=C1)=CC=C1NC([C@@H](C)ONC(C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)=O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (14)
-
Journal Impact Factor
-
Most Recent
-
Exp Mol Med
Glia maturation factor beta deficiency protects against diabetic osteoporosis by suppressing osteoclast hyperactivity. [Abstract]2023 May;55(5):898-909. PMID: 37121966 -
Redox Biol
Myo1f regulates monocyte adhesion and contributes to atherosclerosis via MRTFA-dependent ITGB2 expression. [Abstract]2026 Mar:90:104049. PMID: 41610517 -
Cell Rep
Lysophosphatidic acid and sphingosine-1-phosphate are apical polarity cues in multiple organoid systems. [Abstract]2025 Jun 10;44(6):115842. PMID: 40503936 -
Cell Rep
ENKD1 modulates innate immune responses through enhanced geranylgeranyl pyrophosphate synthase activity. [Abstract]2025 Mar 5;44(3):115397. PMID: 40048432 -
Clin Transl Med
Uterus globulin associated protein 1 (UGRP1) binds podoplanin (PDPN) to promote a novel inflammation pathway during Streptococcus pneumoniae infection. [Abstract]2022 Jun;12(6):e850. PMID: 35652821 -
Cell Biosci
ACTA1 is inhibited by PAX3-FOXO1 through RhoA-MKL1-SRF signaling pathway and impairs cell proliferation, migration and tumor growth in Alveolar Rhabdomyosarcoma. [Abstract]2021 Jan 28;11(1):25. PMID: 33509264 -
Life Sci
Macrophage MKL1 contributes to cardiac fibrosis in a mouse model of myocardial infarction. [Abstract]2024 Aug 31:123036. PMID: 39222836 -
Commun Biol
A genome-scale CRISPR Cas9 dropout screen identifies synthetically lethal targets in SRC-3 inhibited cancer cells. [Abstract]2021 Mar 25;4(1):399. PMID: 33767353 -
Cancers (Basel)
Inhibition of Serum Response Factor Improves Response to Enzalutamide in Prostate Cancer. [Abstract]2020 Nov 27;12(12):3540. PMID: 33260953 -
Tissue Eng Part A
The inhibitory effect of RADKPS on pyroptosis of nucleus pulposus-derived mesenchymal stem cells. [Abstract]2023 Aug;29(15-16):424-438. PMID: 37279291 -
Theriogenology
Influence of Wilms' tumor suppressor gene WT1 on bovine Sertoli cells polarity and tight junctions via non-canonical WNT signaling pathway. [Abstract]2019 Oct 15:138:84-93. PMID: 31302435 -
Arch Dermatol Res
Annexin A1 protects epidermal stem cells against ultraviolet-B irradiation-induced mitochondrial dysfunction. [Abstract]2024 Jun 14;316(7):385. PMID: 38874830 -
Reprod Fertil Dev
Wilms' tumour 1 (WT1) negatively regulates the expression of connexin 43 via a non-canonical Wnt signalling pathway in cultured bovine Sertoli cells. [Abstract]2020 Mar;32(5):522-530. PMID: 32023428 -
bioRxiv
Inhibition of RhoA-mediated secretory autophagy in megakaryocytes mitigates myelofibrosis in mice. [Abstract]2024 Dec 5:2024.12.04.626665. PMID: 39677616
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz