Search Result
Results for "
Solanum
" in MedChemExpress (MCE) Product Catalog:
3
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N0069
-
Solamargine
Maximum Cited Publications
12 Publications Verification
Solamargin; δ-Solanigrine
|
P-glycoprotein
Apoptosis
|
Cancer
|
|
Solamargine, a derivative from the steroidal solasodine in Solanum species, exhibits anticancer activities in numerous types of cancer. Solamargine induces non-selective cytotoxicity and P-glycoprotein inhibition. Solamargine significantly inhibits migration and invasion of HepG2 cells by down-regulating MMP-2 and MMP-9 expression and activity .
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- HY-N0070
-
|
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Ferroptosis
Glutathione Peroxidase
Reactive Oxygen Species (ROS)
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Cancer
|
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Solasonine is a ferroptosis inducer which can be isolated from Solanum melongena that has anti-infection, anti-cancer, and neurogenesis promoting properties. Solasonine promotes ferroptosis of HCC cells via destruction of the glutathione redox system induced by inhibiting GPX4, and can be used for cancer research .
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- HY-N6602
-
-
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- HY-P11056
-
|
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MDM-2/p53
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Others
|
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REF1 peptide is a PORK1 agonist with an EC50 of 0.028 nM in tomato. REF1 peptide binds to the extracellular domain of PORK1, triggers receptor autophosphorylation, and drives downstream MPK3/MPK6 activation, thereby initiating defense and regeneration signaling cascades. REF1 peptide induces callus formation, inhibits shoot regeneration upon continuous exposure, and enhances the regeneration and transformation efficiency of recalcitrant dicotyledonous and monocotyledonous crops .
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-
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- HY-121497
-
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3-MBA
|
PARP
Bacterial
|
Cancer
|
|
3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells . 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum) .
|
-
-
- HY-118020A
-
|
Loliolid; Digiprolactone
|
Endogenous Metabolite
Caspase
PI3K
Apoptosis
Akt
Sirtuin
Reactive Oxygen Species (ROS)
NF-κB
MMP
|
Neurological Disease
Cancer
|
|
Loliolide (Loliolid) is a β-carotene metabolite. Loliolide reduces caspase 3, 8, 9 expression, enhances PI3K, AKT, SIRT1, inhibits ROS, apoptosis, and blocks NF-κB p65 nuclear translocation. Loliolide protects mitochondria, reduces oxidative stress, and increases cell viability in neuroblastoma cells. Loliolide can be used for the research of UV-induced skin damage and Parkinson’s disease .
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- HY-N2322
-
|
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Others
|
Cancer
|
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Khasianine is a steroidal glycoalkaloid which is obtained from black nightshade (Solanum Nigrum L.), which displays antitumor activity.
|
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- HY-N7271
-
|
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RAD51
MDM-2/p53
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Cardiovascular Disease
Cancer
|
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Solanidine is an orally active cholestane alkaloid. Solanidine can be isolated from potato. Solanidine decreases RAD51 and increases γH2AX and p53. Solanidine has anti-tumor effects on LLC tumors and lung cancer. Solanidine promotes breast cancer cell proliferation. Solanidine reduces neovascularization. Solanidine causes abortion in some pregnant mice .
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- HY-NP188
-
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LEL (FITC)
|
Fluorescent Dye
Biochemical Assay Reagents
|
Others
|
|
Lycopersicon esculentum (Tomato) Lectin (FITC) is Lycopersicon esculentum (Tomato) Lectin (HY-NP071) labeled with FITC (HY-66019). Lycopersicon esculentum (Tomato) Lectin (FITC) binds to poly-N-acetyllactosamine oligosaccharides. Lycopersicon esculentum (Tomato) Lectin (FITC) is a major component of carbohydrates on the surface of endothelial and epithelial cells .
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- HY-N1917
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-
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- HY-N4012
-
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3-Indoleglyoxamide
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Others
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Others
|
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Indole-3-glyoxylamide (Compound 4) is a type of indole alkaloid. Indole-3-glyoxylamide shows no significant cytotoxic activity against Hela, Ishikawa, and MGC-803 cells .
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- HY-N9551
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Cytochrome P450
Parasite
COX
Lipoxygenase
|
Infection
Neurological Disease
Cancer
|
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Eriodictyol chalcone is an antioxidant that inhibits multiple key enzymes including 5-LOX (IC50=0.043 μM), aromatase/CYP19A1 (IC50=2.8 μM), PTPase 1B (IC50=1.26 μM), and COX (IC50=34 μM). Eriodictyol chalcone exhibits excellent free radical scavenging activity. Eriodictyol chalcone not only inhibits the growth of plasmodia and enhances the efficacy of Artemisinin (HY-B0094), but also reduces depression-like behaviors in animal models. Eriodictyol chalcone serves as a biosynthetic precursor for Aureusidin (HY-N9834). Eriodictyol chalcone is a potential dietary supplement and herbicide, and it can be applied to research on malaria, depression, breast cancer and other related diseases .
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- HY-E70425
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Glycosyltransferase
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Metabolic Disease
|
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Sucrose synthase belongs to glycosyltransferases and is a reversible catalyst present in plants, which catalyzes the conversion of sucrose into fructose and UDP-G or ADP-G. Sucrose synthase localizes to the cytoplasm, plasma membrane, cell wall, vacuole and mitochondria of plants. Sucrose synthase regulates sugar metabolism, supports the development of taproots, fruits, seeds and vascular tissues, drives the synthesis of starch, cellulose and callose, and enhances nitrogen fixation capacity. Sucrose synthase mediates signal transduction in plant meristems. Sucrose synthase is associated with plant growth, anaerobic stress tolerance, as well as shoot apical meristem and leaf morphology; overexpression of this enzyme promotes plant growth, increases xylem size, and elevates cellulose and starch contents .
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- HY-N11086
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Others
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Metabolic Disease
|
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Tris(dihydrocaffeoyl)spermidine is an active compound. Tris(dihydrocaffeoyl)spermidine can be isolated from potato (Solanum tuberosum) tubers. Tris(dihydrocaffeoyl)spermidine can be used for the research of metabolism .
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- HY-N2231
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|
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Others
|
Metabolic Disease
|
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N-trans-p-coumaroyloctopamine is a phenylpropanoid amide isolated from eggplant (Solanum melongena L.) .
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- HY-N12574
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Others
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Others
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Petunidin-3-(p-coumaroyl-rutinoside)-5-glucoside is an anthocyanin that can be isolated from potatoes (Solanum tuberosum L.) .
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- HY-N6602R
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-
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- HY-NP081
-
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STL
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Fluorescent Dye
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Others
|
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Solanum Tuberosum (Potato) Lectin (STL) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Solanum Tuberosum (Potato) Lectin (STL) is a biological material or organic compound that can be used in life science research .
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- HY-NP0187
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STL (Biotinylated)
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Fluorescent Dye
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Others
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Solanum Tuberosum (Potato) Lectin (STL) Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Solanum Tuberosum (Potato) Lectin (STL) Biotinylated is a biological material or organic compound that can be used in life science research .
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- HY-N12270
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Others
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Others
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Petanin (chloride) is a p-coumaroyl anthocyanin from the tuber epidermis of colored potato (Solanum tuberosum L. cv JAYOUNG) .
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- HY-N11912
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Biochemical Assay Reagents
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Cancer
|
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Soladulcoside A is a steroidal glycoside and antineoplastic agent that can be obtained from the whole plant of Solanum nigrum. Soladulcoside A can inhibit A549 cells and has the potential to study cancers such as non-small cell lung cancer (NSCLC) .
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- HY-N3662
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|
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Others
|
Others
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Cycloartanol is a cycloalkanol compound that can be isolated from the seeds of Solanum dulcamara .
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-
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- HY-N13534
-
|
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Others
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Others
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Torvoside D is a steroid product that can be isolated from Solanum chrysotrichum Schldl .
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-
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- HY-N13502
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|
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Others
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Others
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Neochlorogenin 6-O-β-D-quinovopyranoside is a Triterpene product that can be isolated from Solanum torvum .
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-
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- HY-N2685
-
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5-Pentacosyl-1,3-benzenediol; 1,3-Dihydroxy-5-pentacosylbenzene
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Others
|
Others
|
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5-Pentacosylresorcinol (5-Pentacosyl-1,3-benzenediol) is a Triterpene product that can be isolated from Solanum torvum .
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- HY-N2322R
-
|
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Reference Standards
Others
|
Cancer
|
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Khasianine (Standard) is the analytical standard of Khasianine. This product is intended for research and analytical applications. Khasianine is a steroidal glycoalkaloid which is obtained from black nightshade (Solanum Nigrum L.), which displays antitumor activity.
|
-
-
- HY-N0070R
-
|
|
Reference Standards
Ferroptosis
Glutathione Peroxidase
Reactive Oxygen Species (ROS)
|
Cancer
|
|
Solasonine (Standard) is the analytical standard of Solasonine. This product is intended for research and analytical applications. Solasonine is a ferroptosis inducer which can be isolated from Solanum melongena that has anti-infection, anti-cancer, and neurogenesis promoting properties. Solasonine promotes ferroptosis of HCC cells via destruction of the glutathione redox system induced by inhibiting GPX4, and can be used for cancer research .
|
-
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- HY-N0069R
-
|
Solamargin (Standard); δ-Solanigrine (Standard)
|
P-glycoprotein
Reference Standards
Apoptosis
|
Cancer
|
|
Solamargine (Standard) is the analytical standard of Solamargine. This product is intended for research and analytical applications. Solamargine, a derivative from the steroidal solasodine in Solanum species, exhibits anticancer activities in numerous types of cancer. Solamargine induces non-selective cytotoxicity and P-glycoprotein inhibition. Solamargine significantly inhibits migration and invasion of HepG2 cells by down-regulating MMP-2 and MMP-9 expression and activity .
|
-
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- HY-W017378R
-
|
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Drug Intermediate
Reference Standards
|
Others
|
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Solamargine (Standard) is the analytical standard of Solamargine. This product is intended for research and analytical applications. Solamargine, a derivative from the steroidal solasodine in Solanum species, exhibits anticancer activities in numerous types of cancer. Solamargine induces non-selective cytotoxicity and P-glycoprotein inhibition. Solamargine significantly inhibits migration and invasion of HepG2 cells by down-regulating MMP-2 and MMP-9 expression and activity .
|
-
-
- HY-N8270
-
|
|
Hedgehog
Endogenous Metabolite
|
Cancer
|
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Physalin H is a natural product that can be isolated from Solanum nigrum. Physalin H is an inhibitor of Hedgehog (Hh) signaling and it disrupts GLI1-DNA-complex formation. Physalin H inhibits GLI1 transcription with an IC50 value of 0.7 μM. Physalin H shows cytotoxicity to PANC1 and DU145 cells with IC50 values of 5.7 and 6.8 μM, respectively .
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- HY-121497R
-
|
3-MBA (Standard)
|
PARP
Bacterial
Reference Standards
|
Cancer
|
|
3-Methoxybenzamide (Standard) is the analytical standard of 3-Methoxybenzamide. This product is intended for research and analytical applications. 3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells . 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum) .
|
-
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- HY-N7271R
-
|
|
Reference Standards
RAD51
MDM-2/p53
|
Cardiovascular Disease
Cancer
|
|
Solanidine (Standard) is the analytical standard of Solanidine. This product is intended for research and analytical applications. Solanidine is an orally active cholestane alkaloid. Solanidine can be isolated from potato. Solanidine decreases RAD51 and increases γH2AX and p53. Solanidine has anti-tumor effects on LLC tumors and lung cancer. Solanidine promotes breast cancer cell proliferation. Solanidine reduces neovascularization. Solanidine causes abortion in some pregnant mice .
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-
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- HY-N15309
-
|
Torvoside K
|
Fungal
|
Infection
|
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Torvoside C (Torvoside K) is a compound found in Solanum torvum with antifungal activity. The ZOIs and MIC values of Torvoside C against the tested fungi (Alternaria brassicicola, Alternaria geophila, Aspergillus flavus, etc.) range from 33.4% to 87.4% and 31.25 to 250 μg/mL, respectively. Additionally, it exhibits a dose-dependent inhibitory effect on the production of mycotoxins aflatoxin B1 and fumonisin B1, which are produced by A. flavus and F. verticillioides, respectively. Torvoside C can be used for research in the field of antifungal infection .
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- HY-N12475
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|
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Fungal
Cytochrome P450
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Infection
|
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Solavetivone is a Sesquiterpenoid phytoalexin and Antifungal agent. Solavetivone is isolated from stress-challenged potato plants. Solavetivone is hydroxylated by sesquiterpenoid phytoalexin hydroxylase (SPH/CYP76A2L). Solavetivone helps solanaceous plants defend against pathogens, damages plant cells after pathogen threat, and inhibits mycelial growth of Rhizoctonia solani. Solavetivone is applicable to studies related to Rhizoctonia solani infection .
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- HY-N18755
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- HY-N19427A
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Others
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Others
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Anguivioside XV is a steroidal saponin. Anguivioside XV can be isolated from the fruits of Solanum anguivi .
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- HY-N18350
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Glycosidase
Drug Derivative
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Others
|
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26-Degluco-torvoside H (Compound 4) is a Furostanol glycoside derivative. 26-Degluco-torvoside H forms via hydrolysis of Torvoside H by β-glucosidase from Solanum torvum leaves .
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- HY-N17464
-
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Drug Derivative
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Metabolic Disease
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Methyl (9Z,12Z,14E)-16-hydroxy-9,12,14-octadecatrienoate is an esterified oxylipin and esterified hydroxy linolenic acid (HOT-Me) that can be found in potato tubers (Solanum tuberosum L. cv. Bintje) .
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- HY-N19427
-
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NO Synthase
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Inflammation/Immunology
Cancer
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25S-Anguivioside XV (Compound 8) is a steroidal glycoside. 25S-Anguivioside XV is isolated from the unripe berries of Solanum nigrum L. 25S-Anguivioside XV inhibits LPS-induced NO production with an IC50 of 49.35 μM. 25S-Anguivioside XV exhibits antiproliferative activity against hepatoma cells .
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- HY-N2231R
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-
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- HY-N13524
-
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Others
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Others
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Solagenin 6-O-β-D-quinovopyranoside is a steroid product that can be isolated from Solanum torvum .
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- HY-W540078
-
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Others
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Others
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1,2,3-Trimethylcyclohexane is a volatile compound found in potato tubers (Solanum tuberosum CV: Maris Piper) .
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- HY-W978590
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Drug Derivative
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Others
|
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2-Carene is an active ingredient that can be extracted from Solanum lycopersicum. 2-Carene belongs to monoterpenoid compounds .
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- HY-N16989
-
|
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Others
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Others
|
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Neochlorogenin is a spirostan-type steroidal saponin aglycone that can be naturally extracted from the dried leaves of Solanum torvum Sw. (Indian nightshade) .
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- HY-N19636
-
|
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Others
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Others
|
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N1,N8-Bis(dihydrocaffeoyl) spermidine (Compound B) is dihydrocaffeoyl polyamine found in Solanum tuberosum .
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- HY-N16838
-
|
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Drug Derivative
|
Inflammation/Immunology
|
|
cis-Oxyresveratrol-4'-O-glucoside (compound 2a) is a β-D-glucoside derivative of oxyresveratrol, whose parent compound possesses potential anti-inflammatory, antioxidant, free radical scavenging, and tyrosinase inhibitory activities, and can be used in anti-inflammatory, antioxidant, and whitening-related research. cis-Oxyresveratrol-4'-O-glucoside is a product obtained by the biotransformation of oxyresveratrol using cell suspension cultures of Solanum mammosum (a plant of the genus Solanum in the Solanaceae family) .
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- HY-N9684
-
|
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EGFR
GSK-3
Hedgehog
Akt
ERK
Apoptosis
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Cancer
|
|
Degalactotigonin is a saponin-selective inhibitor targeting the EGFR, GSK3β and Hedgehog/Gli1 pathways and can be isolated from Solanum nigrum (Solanum nigrum). Degalactotigonin inhibits EGFR phosphorylation and the downstream Akt/ERK signaling pathway, and at the same time inhibits the Hedgehog/Gli1 pathway through GSK3β inactivation, thereby inducing cancer cell apoptosis, arresting the cell cycle, and inhibiting migration and invasion. Degalactotigonin can be used in targeted research on malignant tumors such as pancreatic cancer and osteosarcoma .
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- HY-W783913
-
|
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Others
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Others
|
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(9E,12Z)-Methyl-octadecadienoate is a diterpenoid. (9E,12Z)-Methyl-octadecadienoate can be isolated from eggplant fruit .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-NP188
-
|
LEL (FITC)
|
Biochemical Assay Reagents
|
|
Lycopersicon esculentum (Tomato) Lectin (FITC) is Lycopersicon esculentum (Tomato) Lectin (HY-NP071) labeled with FITC (HY-66019). Lycopersicon esculentum (Tomato) Lectin (FITC) binds to poly-N-acetyllactosamine oligosaccharides. Lycopersicon esculentum (Tomato) Lectin (FITC) is a major component of carbohydrates on the surface of endothelial and epithelial cells .
|
-
- HY-NP081
-
|
STL
|
Biochemical Assay Reagents
|
|
Solanum Tuberosum (Potato) Lectin (STL) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Solanum Tuberosum (Potato) Lectin (STL) is a biological material or organic compound that can be used in life science research .
|
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- HY-NP0187
-
|
STL (Biotinylated)
|
Biochemical Assay Reagents
|
|
Solanum Tuberosum (Potato) Lectin (STL) Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Solanum Tuberosum (Potato) Lectin (STL) Biotinylated is a biological material or organic compound that can be used in life science research .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P11056
-
|
|
MDM-2/p53
|
Others
|
|
REF1 peptide is a PORK1 agonist with an EC50 of 0.028 nM in tomato. REF1 peptide binds to the extracellular domain of PORK1, triggers receptor autophosphorylation, and drives downstream MPK3/MPK6 activation, thereby initiating defense and regeneration signaling cascades. REF1 peptide induces callus formation, inhibits shoot regeneration upon continuous exposure, and enhances the regeneration and transformation efficiency of recalcitrant dicotyledonous and monocotyledonous crops .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-N0069
-
-
-
- HY-N0070
-
-
-
- HY-N6602
-
-
-
- HY-118020A
-
|
Loliolid; Digiprolactone
|
Natural Products
Classification of Application Fields
Metabolic Disease
Plants
Compositae
Millettia usaramensis Taub.
Disease Research Fields
Source Classification
|
Endogenous Metabolite
Caspase
PI3K
Apoptosis
Akt
Sirtuin
Reactive Oxygen Species (ROS)
NF-κB
MMP
|
|
Loliolide (Loliolid) is a β-carotene metabolite. Loliolide reduces caspase 3, 8, 9 expression, enhances PI3K, AKT, SIRT1, inhibits ROS, apoptosis, and blocks NF-κB p65 nuclear translocation. Loliolide protects mitochondria, reduces oxidative stress, and increases cell viability in neuroblastoma cells. Loliolide can be used for the research of UV-induced skin damage and Parkinson’s disease .
|
-
-
- HY-N2322
-
-
-
- HY-N7271
-
-
-
- HY-N1917
-
-
-
- HY-N4012
-
-
-
- HY-N9551
-
-
-
- HY-N11086
-
-
-
- HY-N2231
-
-
-
- HY-N12574
-
-
-
- HY-N6602R
-
-
-
- HY-N12270
-
-
-
- HY-N11912
-
-
-
- HY-N3662
-
-
-
- HY-N13534
-
-
-
- HY-N13502
-
-
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- HY-N2685
-
-
-
- HY-N2322R
-
-
-
- HY-N0070R
-
-
-
- HY-N0069R
-
-
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- HY-N8270
-
-
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- HY-N7271R
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-
-
- HY-N15309
-
|
Torvoside K
|
Structural Classification
Solanum torvum Swartz
Solanaceae
Plants
Steroids
Source Classification
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Fungal
|
|
Torvoside C (Torvoside K) is a compound found in Solanum torvum with antifungal activity. The ZOIs and MIC values of Torvoside C against the tested fungi (Alternaria brassicicola, Alternaria geophila, Aspergillus flavus, etc.) range from 33.4% to 87.4% and 31.25 to 250 μg/mL, respectively. Additionally, it exhibits a dose-dependent inhibitory effect on the production of mycotoxins aflatoxin B1 and fumonisin B1, which are produced by A. flavus and F. verticillioides, respectively. Torvoside C can be used for research in the field of antifungal infection .
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-
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- HY-N12475
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-
-
- HY-N18755
-
|
|
Structural Classification
Extract
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Bacterial
|
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Solanum xanthocarpum extract possesses anti-inflammatory, analgesic, antibacterial, and antiviral properties, and is rich in various bioactive compounds, such as alkaloids, triterpenoids, saponins, steroidal glycoalkaloids, and flavonoids.
|
-
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- HY-N19427A
-
-
-
- HY-N18350
-
-
-
- HY-N17464
-
-
-
- HY-N19427
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-
-
- HY-N2231R
-
-
-
- HY-N13524
-
-
-
- HY-W540078
-
-
-
- HY-W978590
-
-
-
- HY-N16989
-
-
-
- HY-N19636
-
-
-
- HY-N16838
-
|
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Structural Classification
Solanum mammosum L.
Phenols
Polyphenols
Solanaceae
Plants
Source Classification
|
Drug Derivative
|
|
cis-Oxyresveratrol-4'-O-glucoside (compound 2a) is a β-D-glucoside derivative of oxyresveratrol, whose parent compound possesses potential anti-inflammatory, antioxidant, free radical scavenging, and tyrosinase inhibitory activities, and can be used in anti-inflammatory, antioxidant, and whitening-related research. cis-Oxyresveratrol-4'-O-glucoside is a product obtained by the biotransformation of oxyresveratrol using cell suspension cultures of Solanum mammosum (a plant of the genus Solanum in the Solanaceae family) .
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-
-
- HY-N9684
-
|
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Plantaginaceae
Digitalis purpurea L.
Structural Classification
Natural Products
Plants
Source Classification
|
EGFR
GSK-3
Hedgehog
Akt
ERK
Apoptosis
|
|
Degalactotigonin is a saponin-selective inhibitor targeting the EGFR, GSK3β and Hedgehog/Gli1 pathways and can be isolated from Solanum nigrum (Solanum nigrum). Degalactotigonin inhibits EGFR phosphorylation and the downstream Akt/ERK signaling pathway, and at the same time inhibits the Hedgehog/Gli1 pathway through GSK3β inactivation, thereby inducing cancer cell apoptosis, arresting the cell cycle, and inhibiting migration and invasion. Degalactotigonin can be used in targeted research on malignant tumors such as pancreatic cancer and osteosarcoma .
|
-
-
- HY-W783913
-
-
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