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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
TGase-2
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "TGase-2" in MCE Product Catalog:
12
12 Cited Publications
Target:
Domaines de recherche:
GK921 is a transglutaminase 2 (TGase) inhibitor with an IC50 of 7.71 μM for human recombinant TGase 2.
Cat. No.: HY-E70437
CAS No.: 80146-85-6
Synonyms: Tissue-type transglutaminase; TG2; TGase 2
Target:
Domaines de recherche:
Guinea pig liver transglutaminase (Tissue-type transglutaminase) is a calcium-dependent tissue-type transglutaminase and serves as the prototype of intracellular tissue transglutaminases purified from guinea pig liver. Guinea pig liver transglutaminase catalyzes acyl transfer reactions via a ping-pong mechanism, forming a transient thioester acyl-enzyme intermediate that mediates the hydrolysis of glutamine amides, displacement by primary amines, and the formation of isopeptide cross-links between peptide-bound glutamine and the amino groups of lysine or polyamines [2] .
Cat. No.: HY-159962
CAS No.: 2244702-64-3
Target:
Domaines de recherche:
TGase2-IN-1 (Compound 22) is an orally active inhibitor for TGase2 with an IC50 of 1.12 μM. TGase2-IN-1 inhibits TGase2 in human retinal microvascular endothelial cells with an IC50 of 0.07 μM. TGase2-IN-1 exhibits 74.6% oral bioavailability. TGase2-IN-1 inhibits retinal vascular leakage in mouse Streptozotocin (HY-13753)-induced diabetic model .
Cat. No.: HY-RS16889
Target:
Domaines de recherche:
Tgm2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tgm2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P76114Y
Pureté: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGM2; Transglutaminase C; Transglutaminase 2; Transglutaminase H; TGC; Transglutaminase-2; Protein-Glutamine Noradrenalinyltransferase TGM2; Heart G Alpha(H); Protein-Glutamine Gamma-Glutamyltransferase 2; HhG Alpha(H); Protein-Glutamine Histaminyltransfe
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P71132A
Pureté: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGM2; Transglutaminase C; Transglutaminase 2; Transglutaminase H; TGC; Transglutaminase-2; Protein-Glutamine Noradrenalinyltransferase TGM2; Heart G Alpha(H); Protein-Glutamine Gamma-Glutamyltransferase 2; HhG Alpha(H); Protein-Glutamine Histaminyltransfe
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P78361
Pureté: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TGM2; Transglutaminase C; Transglutaminase 2; Transglutaminase H; TGC; Transglutaminase-2; Protein-Glutamine Noradrenalinyltransferase TGM2; Heart G Alpha(H); Protein-Glutamine Gamma-Glutamyltransferase 2; HhG Alpha(H); Protein-Glutamine Histaminyltransfe
Species:
Mouse
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
