39 Results for "

TM4

" in MedChemExpress (MCE) Product Catalog:
Products (39)

39 Results for "TM4" in MCE Product Catalog:

Cat. No.: HY-N5109
CAS No.: 138664-32-1
Cheilanthifoline, an alkaloid, is isolated from Corydalis calliantha. Cheilanthifoline exhibits antiplasmodial activities against Plasmodium falciparum, with IC50s of 0.90 μg/mL and 1.22 μg/mL for wild type (TM4) and multidrug resistant (K1) strains, respectively .
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Cat. No.: HY-N5005
CAS No.: 4758-99-0
Synonyms: Atisinium chloride
Guanfu base H (Atisinium chloride) is a diterpenoid alkaloid isolated from Aconitum coreanum and has antiplasmodial activity against the malarial Plasmodium falciparum strains TM4/8.2 (wild type) and K1CB1 with IC50 values of 4 μM and 3.6 μM, respectively .
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Cat. No.: HY-P990521

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

The Anti-TM4SF1 Antibody is a CHO-expressed human antibody that targets TM4SF1. The Anti-TM4SF1 Antibody is equipped with a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for the Anti-TM4SF1 Antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P991187
Synonyms: AGX-101 Antibody
Research Areas:  

Cancer

Anti-TM4SF1 Antibody (AGX-A07) is a humanized IgG1 monoclonal antibody that targets TM4SF1. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-129359
CAS No.: 160580-70-1
Purity:  98.27%
Target:  

ADC Linkers

Research Areas:  

Cancer

PDP-Pfp is a reducible ADC Linker used as an active molecule targeting the extracellular loop 1 (ECL1) of TM4SF1 .
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Cat. No.: HY-143862
CAS No.: 2340432-40-6
Target:  

PPAR

Research Areas:  

Metabolic Disease

Pparδ agonist 7 is a potent agonist of Pparδ. The peroxisome proliferator-activated receptor (PPAR) is a member of the intranuclear receptor transcription factor superfamily that plays a key role in the regulation of metabolic homeostasis, inflammation, cell growth and differentiation in vivo. Pparδ agonist 7 has the potential for the research of non-alcoholic fatty liver disease (NAFLD) (extracted from patent WO2019105234A1, compound TM4) .
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Cat. No.: HY-P10874
Target:  

Bacterial

Research Areas:  

Infection

SMR efflux inhibitor targets the small multidrug resistance (SMR) efflux pump, blocks the interaction of TM4-TM4, and exhibits board-spectrum antibacterial activity .
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Cat. No.: HY-W012423
CAS No.: 2645-22-9
Synonyms: Aldrithiol(TM)-4
Target:  

MOFs

Research Areas:  

Others

1,2-Di(pyridin-4-yl)disulfane (Aldrithiol(tm)-4) is a metal-organic framework (MOF).
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Cat. No.: HY-160789
CAS No.: 2415154-29-7
C3001a is a selective TREK-1 and TREK-2 channel activator with EC50 values of 12.81 μM and 11.31 μM, respectively. C3001a does not affect other two-pore domain K + (K2P) channels. C3001a binds to the cryptic binding site formed by P1 and TM4 in TREK-1. C3001a can be used for the study of pain and pancreatitis .
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Cat. No.: HY-168069
Research Areas:  

Infection

DHFR-IN-20 (Compound LA1) is a Plasmodium falciparum dihydrofolate reductase (DHFR) inhibitor, with Kis of 0.16, 0.30, 6.6 nM for PfDHFR-WT, PfDHFR-QM, HsDHFR. DHFR-IN-20 has antimalarial activities (IC50: 1.4 nM and 1.6 μM for P. falciparum carrying the wild-type (TM4/8.2) and the quadruple mutant (V1/S) PfDHFR enzyme .
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Cat. No.: HY-129372
CAS No.: 2101206-44-2
Target:  

ADC Linkers

Research Areas:  

Cancer

PDdB-Pfp is a cleavable ADC linker used for the agents that target for the extracellular loop 1 (ECL1) of TM4SF1 (transmembrane 4 L6 family member 1) .
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Cat. No.: HY-RS14606
Research Areas:  

Others

TM4SF1 Human Pre-designed siRNA Set A contains three designed siRNAs for TM4SF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS14607
Research Areas:  

Others

TM4SF19 Human Pre-designed siRNA Set A contains three designed siRNAs for TM4SF19 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS14608
Research Areas:  

Others

TM4SF20 Human Pre-designed siRNA Set A contains three designed siRNAs for TM4SF20 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS14609
Research Areas:  

Others

TM4SF4 Human Pre-designed siRNA Set A contains three designed siRNAs for TM4SF4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS14610
Research Areas:  

Others

TM4SF5 Human Pre-designed siRNA Set A contains three designed siRNAs for TM4SF5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS19821
Research Areas:  

Others

Tm4sf1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tm4sf1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS26317
Research Areas:  

Others

Tm4sf1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tm4sf1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P84875
Synonyms: TM-8; TM4-B; TM4SF16

Host:  

Mouse

Application:  

WB, IHC-P, FC, ELISA

Reactivity:  

Human, Mouse, Rat, Monkey

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Cat. No.: HY-P84875A
Synonyms: TM-8; TM4-B; TM4SF16

Host:  

Mouse

Application:  

WB, IHC-P, FC, ELISA

Reactivity:  

Human, Mouse, Rat, Monkey

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