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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
41 Results for "
TM4
" in MedChemExpress (MCE) Product Catalog:
Products (41)
41 Results for "TM4" in MCE Product Catalog:
Cat. No.: HY-N5109
CAS No.: 138664-32-1
Category:
Infection Alkaloids other families Monophenols Phenols Plants Disease Research Fields Isoquinoline Alkaloids
Target:
Category:
Infection Alkaloids Ranunculaceae Quinoline Alkaloids Aconitum carmichaeli Debx. Plants Disease Research Fields
Target:
Synonyms: R-40244
Research Areas:
Flurochloridone (R-40244) is a selective preemergence and persistent herbicide. Flurochloridone induces endoplasmic reticulum (ER) stress and activated unfolded protein response (UPR) signaling pathways. Flurochloridone impairs cell viability and induces cytotoxicity and apoptosis mediated by ER stress via activating eIF2α-ATF4/ATF6-CHOP-Bim/Bax signaling pathways in TM4 cells .
Cat. No.: HY-P990521
Target:
Research Areas:
Cat. No.: HY-P991187
Synonyms: AGX-101 Antibody
Target:
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PDP-Pfp is a reducible ADC Linker used as an active molecule targeting the extracellular loop 1 (ECL1) of TM4SF1 .
Cat. No.: HY-143862
CAS No.: 2340432-40-6
Target:
Research Areas:
Pparδ agonist 7 is a potent agonist of Pparδ. The peroxisome proliferator-activated receptor (PPAR) is a member of the intranuclear receptor transcription factor superfamily that plays a key role in the regulation of metabolic homeostasis, inflammation, cell growth and differentiation in vivo. Pparδ agonist 7 has the potential for the research of non-alcoholic fatty liver disease (NAFLD) (extracted from patent WO2019105234A1, compound TM4) .
Cat. No.: HY-W012423
CAS No.: 2645-22-9
Synonyms: Aldrithiol(TM)-4
1,2-Di(pyridin-4-yl)disulfane (Aldrithiol(tm)-4) is a metal-organic framework (MOF).
Cat. No.: HY-160789
CAS No.: 2415154-29-7
Target:
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C3001a is a selective TREK-1 and TREK-2 channel activator with EC50 values of 12.81 μM and 11.31 μM, respectively. C3001a does not affect other two-pore domain K + (K2P) channels. C3001a binds to the cryptic binding site formed by P1 and TM4 in TREK-1. C3001a can be used for the study of pain and pancreatitis .
Cat. No.: HY-168069
Research Areas:
DHFR-IN-20 (Compound LA1) is a Plasmodium falciparum dihydrofolate reductase (DHFR) inhibitor, with Kis of 0.16, 0.30, 6.6 nM for PfDHFR-WT, PfDHFR-QM, HsDHFR. DHFR-IN-20 has antimalarial activities (IC50: 1.4 nM and 1.6 μM for P. falciparum carrying the wild-type (TM4/8.2) and the quadruple mutant (V1/S) PfDHFR enzyme .
Cat. No.: HY-129372
CAS No.: 2101206-44-2
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PDdB-Pfp is a cleavable ADC linker used for the agents that target for the extracellular loop 1 (ECL1) of TM4SF1 (transmembrane 4 L6 family member 1) .
Cat. No.: HY-121337R
CAS No.: 61213-25-0
Synonyms: R-40244 (Standard)
Target:
Research Areas:
Flurochloridone (Standard) is the analytical standard of Flurochloridone. This product is intended for research and analytical applications. Flurochloridone (R-40244) is a selective preemergence and persistent herbicide. Flurochloridone induces endoplasmic reticulum (ER) stress and activated unfolded protein response (UPR) signaling pathways. Flurochloridone impairs cell viability and induces cytotoxicity and apoptosis mediated by ER stress via activating eIF2α-ATF4/ATF6-CHOP-Bim/Bax signaling pathways in TM4 cells .
Cat. No.: HY-RS14606
Target:
Research Areas:
TM4SF1 Human Pre-designed siRNA Set A contains three designed siRNAs for TM4SF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14607
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TM4SF19 Human Pre-designed siRNA Set A contains three designed siRNAs for TM4SF19 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14608
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TM4SF20 Human Pre-designed siRNA Set A contains three designed siRNAs for TM4SF20 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14609
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TM4SF4 Human Pre-designed siRNA Set A contains three designed siRNAs for TM4SF4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14610
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Research Areas:
TM4SF5 Human Pre-designed siRNA Set A contains three designed siRNAs for TM4SF5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19821
Target:
Research Areas:
Tm4sf1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tm4sf1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26317
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Tm4sf1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tm4sf1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
