19 Results for "

U-2 OS/PD-L1/SNAPtag cells

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "U-2 OS/PD-L1/SNAPtag cells" in MCE Product Catalog:

Cat. No.: HY-131028
Purity:  ≥95.0%
Synonyms: JF646 TFA
Janelia Fluor 646 TFA (JF646 TFA), a red fluorogenic fluorescent dye, can be used in the synthesis of Janelia Fluor 646 HaloTag and SNAP-Tag ligands. JF646 TFA is used in live cell imaging experiments . Janelia Fluor fluorescent dyes can be chemically conjugated to the specific HaloTag substrate (a chloroalkane ligand) to form a fluorescent ligand, rather than binding directly to the HaloTag protein itself. Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute (Ex/Em = 646/664 nm).
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Cat. No.: HY-136936
CAS No.: 2068027-79-0
Purity:  98.27%
PYBG-BODIPY is a dye and has a role as a fluorochrome. PYBG-BODIPY specifically and efficiently labels the target genetically encoded SNAP-tags in live cells .
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Cat. No.: HY-130736
CAS No.: 1811539-32-8
Synonyms: JF549, SE; JF549, NHS
Janelia Fluor? 549, SE (JF549, SE) is a cell-permeable fluorescent dye with an NHS ester (succinimidyl ester (SE)) reactive group. NHS esters react with primary amines and are commonly used to conjugate dyes to proteins, antibodies, amine-modified oligonucleotides, and other molecules. Janelia Fluor fluorescent dyes can be chemically conjugated to the specific HaloTag substrate (a chloroalkane ligand) to form a fluorescent ligand, rather than binding directly to the HaloTag protein itself. Janelia Fluor? 549, SE also acts as a ligand for self-labeling tags such as HaloTag and SNAP-tag, and can be used in live-cell imaging studies (Ex/Em = 549 nm/571 nm) .
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Cat. No.: HY-148958
CAS No.: 471918-16-8
Research Areas:  

Others

SNAP-Biotin is a cell-permeable SNAP-tag-targeted labeling reagent. SNAP-Biotin undergoes an irreversible covalent reaction with SNAP-tag to transfer biotin to the tag. SNAP-Biotin enables the detection of SNAP-tag fusion proteins via a streptavidin-HRP immunoblotting system and achieves biotinylation of SNAP-tag fusion proteins. SNAP-Biotin is applicable to triple-negative breast cancer-related research .
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Cat. No.: HY-136937
CAS No.: 2067339-51-7
PYBG-TMR is a dye and has a role as a fluorochrome. PYBG-TMR specifically and efficiently labels the target genetically encoded SNAP-tags in live cells . PYBG-TMR is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No.: HY-D2994
CAS No.: 2434651-49-5
Synonyms: SNAP-MaP555
Target:  

Fluorescent Dye

Research Areas:  

Others

SPY555-BG (SNAP-MaP555) is a cell-permeable fluorescent dye for SNAP-tag labeling of HIV-1 Gag, which enables visualization of HIV-1 intercellular transmission via SNAPf. SPY555-BG relies on irreversible covalent binding to the active-site cysteine of the SNAPf tag fused to HIV-1 Gag .
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Cat. No.: HY-D2933
Target:  

Fluorescent Dye

Research Areas:  

Others

SNAP-505 is a cell-permeable green fluorescent dye (Ex/Em ≈504/532 nm). It binds specifically and covalently to SNAP-tag fusion proteins, and is used for pulse-chase labeling and localization tracking of proteins in living cells. SNAP-505 can be applied to studies related to insulin granule formation, ER-Golgi protein trafficking, and other relevant processes .
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Cat. No.: HY-D2949
CAS No.: 2836233-28-2
SNAP-549 is a DY-549P1-labeled SNAP tag fluorescent probe, specifically designed for single-molecule imaging and dynamic tracking of proteins in living cells. SNAP-549 only labels SNAP-tag fusion proteins, with low background signals and forming irreversible connections, making it suitable for long-term observation .
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Cat. No.: HY-W1124386
CAS No.: 1820756-74-8
Synonyms: SNAP-DBCO
BG-DBCO (SNAP-DBCO) is a key bifunctional reagent that acts as a "bridge" in the ClickRNA-PROTAC system. BG-DBCO possesses a SNAPTag covalent anchoring handle and a copper-free click chemistry handle: one end covalently locks SNAPTag fusion proteins via BG, while the other end captures azide-modified target protein ligands through copper-free click chemistry (SPAAC), thereby assembling the "exogenous E3 fusion protein" and "POI ligand" into a complete PROTAC ternary complex in living cells .
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Cat. No.: HY-D2948
CAS No.: 928760-60-5
SNAP-430 is a (diethylamino) coumarin-labeled SNAP tag fluorescent probe. SNAP-430 can be used for making SNAP-tag fusion proteins inside living cells, on cell surfaces, or in vitro.
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Cat. No.: HY-D2984
CAS No.: 1308789-62-9
Synonyms: SNAP-PEG-NH2
Target:  

Fluorescent Dye

Research Areas:  

Others

BG-PEG-NH2 (SNAP-PEG-NH2) is an amino-terminal fluorescent probe building block and a precursor for site-specific labeling of SNAP-tag fusion proteins. BG-PEG-NH2 undergoes one-step coupling with activated carboxyl esters to form customized SNAP-tag substrates, which covalently bind to SNAP tags via a thioether bond formed at the Cys145 site. After coupling with a caged carboxyfluorescein, BG-PEG-NH2 forms a probe with Ex/Em = 500/524 nm following ultraviolet uncaging. Coupling of BG-PEG-NH2 with SeTau-647-NHS enables visualization of GPCR signal transduction. BG-PEG-NH2 is suitable for coupling reactions in aqueous phases or buffers, conjugation of labels, and labeling of intracellular or cell-surface proteins .
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Cat. No.: HY-D3367
Research Areas:  

Others

Th-TMR-S-SNAP is a fluorescent probe used for SNAP-tag labeling and wash-free live-cell imaging of intracellular SNAP-tag fusion proteins. The excitation wavelength of Th-TMR-S-SNAP is 561 nm, and its emission wavelength ranges from 570 to 620 nm .
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Cat. No.: HY-D2925
Synonyms: dTCO-SNAP
dTCOBG (dTCO-SNAP) is a SNAP-tag reactive benzylguanine (BG) analogue specifically designed for the specific labeling of immune cells. dTCOBG forms a stable thioether bond through the cysteine at the active site of SNAP-tag and O6-benzylguanine, resulting in a covalent linkage. dTCOBG demonstrates unique advantages in the labeling of macrophages derived from ER-HoxB8: it only labels SNAP-tag + macrophages, with no background signal in the control group. dTCOBG can be used for click chemistry labeling .
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Cat. No.: HY-D3603
CAS No.: 928817-42-9
Research Areas:  

Others

Benzylguanine-CY5 is a quenched fluorescent dye conjugate based on benzylguanine (BG). Benzylguanine-CY5 possesses the activity of specifically covalently labeling SNAP-tag fusion proteins. Benzylguanine-CY5 exhibits intramolecular fluorescence quenching in the unbound state; upon binding to SNAP-tag, the quenching guanine moiety is cleaved, and its fluorescence intensity increases. Benzylguanine-CY5 can be used for background-free specific fluorescent labeling and imaging studies of SNAP-tag fusion proteins in living cells .
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Cat. No.: HY-D2941
Synonyms: SNAP-AF
BGAF (SNAP-AF) is a fluorescent diacetyl fluorescein-labeled SNAP tag fluorescent probe, specifically designed for the covalent labeling of SNAP-tag fusion proteins in living cells. BGAF utilizes the specific reaction of the human DNA repair protein hAGT to achieve specific fluorescent labeling of the target protein in the living cell environment .
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Cat. No.: HY-D2935
CAS No.: 680622-88-2
CoDi3 is a covalent dimerization inducer. CoDi3 can specifically, covalently and irreversibly induce the dimerization of two proteins that have been fused with O6-alkylguanine-DNA alkyltransferase (AGT, also known as SNAP-tag) in living cells. CoDi3 can act as a "sensor" for protein-protein interactions .
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Cat. No.: HY-D2995
CAS No.: 945966-30-3
CoDi3 is a covalent dimerization inducer. CoDi3 can specifically, covalently and irreversibly induce the dimerization of two proteins that have been fused with O6-alkylguanine-DNA alkyltransferase (AGT, also known as SNAP-tag) in living cells. CoDi3 can act as a "sensor" for protein-protein interactions .
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Cat. No.: HY-D2939
CAS No.: 1622078-12-9
BGSBD is a SNAP-tag-based fluorescent probe (Ex/Em: 435 nm/516 nm) based on the environmentally sensitive fluorescent group SBD, specifically designed for protein labeling of live cells without washing. BGSBD achieves a 280-fold fluorescence enhancement after labeling by ingeniously utilizing the hydrophobic binding pocket of the SNAP-tag protein, providing an ideal tool for real-time monitoring of protein dynamics within cells .
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Cat. No.: HY-D2930
Synonyms: SNAP-SS-SulfoCy5
BG-SS-SulfoCy5 (SNAP-SS-SulfoCy5) is a SulfoCy5-labeled SNAP tag fluorescent probe, linked by a disulfide bond. BG-SS-SulfoCy5 combines the specific recognition of SNAP-tag, the cleavability of disulfide bond, and the excellent optical properties of SulfoCy5. BG-SS-SulfoCy5 can be used for tracking the internalization of cell surface proteins and multiple labeling experiments .
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