13 Results for "

VEGF-B

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "VEGF-B" in MCE Product Catalog:

  • Recombinant Proteins Recommended:
3
3 Cited Publications
Cat. No.: HY-P72431
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Vascular endothelial growth factor B; VEGF-B; VRF
Species:  
Source:  
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Cat. No.: HY-P990540
Synonyms: CSL346; Reflocibart

Target:  

VEGFR

Research Areas:  

Metabolic Disease

Anti-VEGFB Antibody (CSL346; Reflocibart) is a humanized IgG4κ monoclonal antibody targeting VEGF-B, which binds to VEGF-B with high affinity to reduce its activity. Anti-VEGFB Antibody (CSL346) inhibits ectopic lipid deposition in the kidney, improves the histological manifestations of glomerular injury, and reduces proteinuria in animal models. Anti-VEGFB Antibody (CSL346) can be used in studies related to diabetic nephropathy .
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Cat. No.: HY-P99830
CAS No.: 1227158-72-6
Synonyms: KH902
Conbercept (KH902) is a recombinant fusion protein composed of VEGFR-1 (second domain) and VEGFR-2 (third and fourth domains) regions fused to human IgG1 Fc. Conbercept is a VEGF inhibitor (IC50 = 8.8 pM) and is a soluble receptor decoy that blocks all isoforms of VEGF-A (Kd = 0.5 pM), VEGF-B (Kd = 8 pM), VEGF-C, and PlGF (Kd = 5 pM). Conbercept has anti-inflammatory effects, can lower the levels of VEGF, TNF-α and IL-6, and reduce the infiltration of inflammatory cells. Conbercept decreases tumor growth in several oncology studies. Conbercept can be used for various eye diseases such as polypoidal choroidal vasculopathy (PCV), diabetic macular edema (DME) and pathologic myopia choroidal neovascularization (pmCNV) .
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Cat. No.: HY-P10831
CAS No.: 853995-60-5
Target:  

VEGFR

Research Areas:  

Cardiovascular Disease Cancer

GNQWFI, an anti-Flt1 peptide, is a VEGFR1-specific antagonist. GNQWFI blocks the interaction of VEGFR1 with various VEGFR1 ligands, such as VEGFA, VEGFB, and placental growth factor (PIGF) and inhibits VEGF-induced endothelial cell migration and tube formation. GNQWFI is promising for research of cancer, asthma, and other ocular diseases .
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Cat. No.: HY-P10550
Target:  

VEGFR

Research Areas:  

Cancer

VGB4 is a VEGF-A and VEGF-B antagonist peptide that duplicates two binding domains of VEGF-B (loop 1 and loop3) and are linked together by the receptor-binding domain of VEGF-A (loop3). VGB4 has significant anti-angiogenic and anti-tumor activities and can regulate tumor growth and metastasis through multiple mechanisms. VGB4 could be used in anti-tumor research .
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Cat. No.: HY-RS18083
Research Areas:  

Others

Vegfb Mouse Pre-designed siRNA Set A contains three designed siRNAs for Vegfb gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-174509
Target:  

mRNA

Research Areas:  

Cancer

Human VEGFB mRNA encodes the human vascular endothelial growth factor B (VEGFB) protein, a member of the platelet-derived growth factor (PDGF)/ vascular endothelial growth factor (VEGF) family. VEGFB is a growth factor for endothelial cells.
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Cat. No.: HY-RS15636
Research Areas:  

Others

VEGFB Human Pre-designed siRNA Set A contains three designed siRNAs for VEGFB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS24557
Research Areas:  

Others

Vegfb Rat Pre-designed siRNA Set A contains three designed siRNAs for Vegfb gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P82882
Synonyms: VEGFB; VRF; Vascular endothelial growth factor B; VEGF-B; VEGF-related factor; VRF

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse

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Cat. No.: HY-N19029
CAS No.: 21871-10-3
Vernodalin is an orally active, cytotoxic sesquiterpene lactone with a Kd value of 9.55 μM for p38 MAPK. Vernodalin downregulates the expression of phosphorylated ERK, JNK, AKT, PI3K, mTOR, p38MAPK, FAK, MMP-2, MMP-9, and uPA, while upregulates the expression of TIMP-1 and TIMP-2. Vernodalin increases ROS production, upregulates the expression of Bax and caspase 3, downregulates the expression of Bcl-2, and induces apoptosis (apoptosis), oxidative stress response and cell cycle arrest. Vernodalin inhibits the proliferation, adhesion and metastasis of cancer cells. Vernodalin enhances the activity of VEGF-B, AMPK and eNOS signaling pathways. Vernodalin alleviates myocardial injury and restores hemodynamic parameters. Vernodalin inhibits the growth of Trypanosoma brucei rhodesiense. Vernodalin can be used in research related to various cancers including gastric cancer, colorectal cancer and lung cancer, as well as African human trypanosomiasis and myocardial infarction .
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Cat. No.: HY-P11775A
Target:  

VEGFR

Research Areas:  

Cardiovascular Disease

Peptide HRH acetate is a polypeptide that specifically binds to VEGF receptors. Peptide HRH acetate inhibits VEGF-stimulated endothelial cell proliferation. Peptide HRH acetate inhibits angiogenesis and suppresses corneal neovascularization. Peptide HRH acetate can be used in anti-angiogenesis related studies .
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Cat. No.: HY-P11775
CAS No.: 1228536-06-8
Target:  

VEGFR

Research Areas:  

Cardiovascular Disease

Peptide HRH is a polypeptide that specifically binds to VEGF receptors. Peptide HRH inhibits VEGF-stimulated endothelial cell proliferation. Peptide HRH inhibits angiogenesis and suppresses corneal neovascularization. Peptide HRH can be used in anti-angiogenesis related studies .
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