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VLA-2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Integrin (1) Small Interfering RNA (siRNA) (1)
By Research Areas:	Inflammation/Immunology (1) Neurological Disease (1)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

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Vatelizumab GBR500	Integrin	Neurological Disease Inflammation/Immunology
Vatelizumab (GBR500) is a monoclonal antibody that targets the α2 subunit (CD49b) of very late antigen 2 (VLA-2). Vatelizumab can be used for research on multiple sclerosis .

ITGA2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ITGA2 Human Pre-designed siRNA Set A contains three designed siRNAs for ITGA2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.	Product Name	Target	Research Area	Image

HY-P99524

Vatelizumab GBR500	Integrin	Neurological Disease Inflammation/Immunology
Vatelizumab (GBR500) is a monoclonal antibody that targets the α2 subunit (CD49b) of very late antigen 2 (VLA-2). Vatelizumab can be used for research on multiple sclerosis .

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P700752

	Integrin alpha 2 beta 1 Protein, Human (HEK293, His) 1 Publications Verification α2β1; Integrin alpha A1 beta 1; alpha A1 beta 1; alpha A1; beta 1; ITGA1&ITGB1; ITGA&ITGB; VLA-2, GPIa-IIa, CD49b; Integrin alpha A1 β 1; alpha A1 β 1; β 1	Human	HEK293
	ITGA2 Protein, a transmembrane receptor, is involved in cell adhesion, platelet aggregation, and tumor metastasis. Dysregulation of ITGA2 Protein has been associated with various disorders, including thrombosis and cancer. Targeting ITGA2 Protein may offer potential therapeutic interventions in these conditions by modulating cell adhesion, inhibiting blood clot formation, and preventing tumor metastasis. Integrin alpha 2 beta 1 Protein, Human (HEK293, His) is a recombinant protein dimer complex containing human-derived Integrin alpha 2 beta 1 protein, expressed by HEK293 , with C-His labeled tag. Integrin alpha 2 beta 1 Protein, Human (HEK293, His), has molecular weight of 110-140 kDa.

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Host:	Mouse (4) Rabbit (1)
Reactivity:	Human (5) Rat (3) Mouse (3)
Application:	IHC-P (3) ICC/IF (5) IF-Tissue (2) IP (1) IHC-F (2) WB (1) FC (3) ELISA (2)
Isotype:	IgG (3) IgG1 (2)
Conjugation:	Non-conjugated (5)
Clonality:	Monoclonal (4) Recombinant (1)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P84137

	Integrin alpha 2 Antibody (YA3834) ITGA2; BR; GPIa; HPA-5; VLA-2; VLAA2	ICC/IF, FC, ELISA	Human
	Integrin alpha 2 Antibody (YA3834) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Integrin alpha 2.

HY-P84137A

	Integrin alpha 2 Antibody (YA3834)(PBS only) ITGA2; BR; GPIa; HPA-5; VLA-2; VLAA2	ICC/IF, FC, ELISA	Human
	Integrin alpha 2 Antibody (YA3834) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Integrin alpha 2.

HY-P83362

	Integrin alpha 2 Antibody (YA3107) ITGA2; CD49B; Integrin alpha-2; CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia; GPIa; VLA-2 subunit alpha; CD49b	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	Integrin alpha 2 Antibody (YA3107) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Integrin alpha 2.

HY-P86740

	PTEN Antibody (YA6432) ITGA 2; MGC11227; MHAM; MMAC 1; MMAC1; Bannayan Zonana; BZS a; Multiple hamartoma(Cowden syndrome); Mutated in Mutiple Advanced Cancers 1; Phosphatase and Tensin Homolog; Phosphatidylinositol 345 trisphosphate 3 phosphatase and dual specificity protein phosphatase PTEN; Phosphatidylinositol 345 trisphosphate 3 phosphatase; Platelet antigen BR; PTEN 1; PTEN1; Tensin homolog; TEP 1; TEP1; VLA 2 Receptor alpha Subunit.	IHC-P, IHC-F, ICC/IF, IF-Tissue	Human, Mouse, Rat
	PTEN Antibody (YA6432) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to PTEN.

HY-P86740A

	PTEN Antibody (YA6432)(PBS only) ITGA 2; MGC11227; MHAM; MMAC 1; MMAC1; Bannayan Zonana; BZS a; Multiple hamartoma(Cowden syndrome); Mutated in Mutiple Advanced Cancers 1; Phosphatase and Tensin Homolog; Phosphatidylinositol 345 trisphosphate 3 phosphatase and dual specificity protein phosphatase PTEN; Phosphatidylinositol 345 trisphosphate 3 phosphatase; Platelet antigen BR; PTEN 1; PTEN1; Tensin homolog; TEP 1; TEP1; VLA 2 Receptor alpha Subunit.	IHC-P, IHC-F, ICC/IF, IF-Tissue	Human, Mouse, Rat
	PTEN Antibody (YA6432) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to PTEN.

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HY-RS06948

ITGA2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ITGA2 Human Pre-designed siRNA Set A contains three designed siRNAs for ITGA2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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