8 Results for "

Vincamine

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "Vincamine" in MCE Product Catalog:

8
Vinpocetine
Vinpocetine
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8 Publications Verification
Cat. No.: HY-13295
CAS No.: 42971-09-5
Purity:  99.57%
Synonyms: Ethyl apovincaminate
Category:  

Cardiovascular Disease Neurological Disease Anti-aging Plants Indole Alkaloids Catharanthus roseus (L.) G. Don Apocynaceae Alkaloids Piperidine Alkaloids Disease Research Fields Cancer

Target:  

Sodium Channel IKK Phosphodiesterase (PDE)

Vinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na + channels. The IC50 value of Vinpocetine on direct IKK inhibition in the cell-free system is 17.17 μM. Vinpocetine is a phosphodiesterase (PDE) inhibitor and inhibits NF-κB-dependent inflammatory responses by directly targeting IκB kinase complex (IKK), and has been widely used for the treatment of cerebrovascular disorders .
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3
Vinburnine
Vinburnine
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3 Cited Publications
Cat. No.: HY-B1180
CAS No.: 4880-88-0
Synonyms: (-)-Eburnamonine; (-)-Vincamone
Category:  

Cardiovascular Disease Apocynaceae Alkaloids Hunteria zeylanica Plants Disease Research Fields Indole Alkaloids

Target:  

Drug Metabolite mAChR

Vincamone is a vinca alkaloid and a metabolite of vincamine, is a vasodilator.
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1
Vincamine
Vincamine
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1 Cited Publications
Cat. No.: HY-B1021
CAS No.: 1617-90-9
Category:  

Cardiovascular Disease Apocynaceae Alkaloids Plants Disease Research Fields Indole Alkaloids Catharanthus roseus (L.) G. Don

Target:  

Free Fatty Acid Receptor

Vincamine is a monoterpenoid indole alkaloid extracted from the Madagascar periwinkle. Vincamine is a peripheral vasodilator and exerts a selective vasoregulator action on the brain microcapilar circulation . Vincamine is a GPR40 agonist and acts as a β-cell protector by ameliorating β-cell dysfunction and promoting glucose-stimulated insulin secretion (GSIS). Vincamine improves glucose homeostasis in vivo, and has the potential for the type 2 diabetes mellitus (T2DM) research .
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Vinpocetine (Standard)
Vinpocetine (Standard)
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Cat. No.: HY-13295R
CAS No.: 42971-09-5
Synonyms: Ethyl apovincaminate (Standard)
Category:  

Apocynaceae Alkaloids Piperidine Alkaloids Plants Indole Alkaloids Catharanthus roseus (L.) G. Don

Target:  

Reference Standards Sodium Channel IKK Phosphodiesterase (PDE)

Vinpocetine (Standard) is the analytical standard of Vinpocetine. This product is intended for research and analytical applications. Vinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na + channels. The IC50 value of Vinpocetine on direct IKK inhibition in the cell-free system is 17.17 μM. Vinpocetine is a phosphodiesterase (PDE) inhibitor and inhibits NF-κB-dependent inflammatory responses by directly targeting IκB kinase complex (IKK), and has been widely used for the treatment of cerebrovascular disorders .
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Vincamine (Standard)
Vincamine (Standard)
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Cat. No.: HY-B1021R
CAS No.: 1617-90-9
Category:  

Apocynaceae Alkaloids Plants Indole Alkaloids Catharanthus roseus (L.) G. Don

Target:  

Reference Standards Free Fatty Acid Receptor

Vincamine (Standard) is the analytical standard of Vincamine. This product is intended for research and analytical applications. Vincamine is a monoterpenoid indole alkaloid extracted from the Madagascar periwinkle. Vincamine is a peripheral vasodilator and exerts a selective vasoregulator action on the brain microcapilar circulation . Vincamine is a GPR40 agonist and acts as a β-cell protector by ameliorating β-cell dysfunction and promoting glucose-stimulated insulin secretion (GSIS). Vincamine improves glucose homeostasis in vivo, and has the potential for the type 2 diabetes mellitus (T2DM) research .
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14α/β-Vindeburnol
14α/β-Vindeburnol
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Cat. No.: HY-105058A
Synonyms: 14α/β-RU 24722
Target:  

Drug Derivative

Research Areas:  

Neurological Disease

14α/β-Vindeburnol (14α/β-RU 24722) a synthetic molecule derived from the eburnamine-vincamine alkaloid group, has many neuropsychopharmacological and antidepressant-like effects .
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Vinpocetine-d5
Vinpocetine-d5
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Cat. No.: HY-13295S
CAS No.: 2734920-39-7
Vinpocetine-d5 is the deuterium labeled Vinpocetine. Vinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na+ channels. The IC50 value of Vinpocetine on direct IKK inhibition in the cell-free system is 17.17 μM. Vinpocetine is a phosphodiesterase (PDE) inhibitor and inhibits NF-κB-dependent inflammatory responses by directly targeting IκB kinase complex (IKK), and has been widely used for the treatment of cerebrovascular disorders .
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AF 698
AF 698
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Cat. No.: HY-129406
CAS No.: 82958-11-0
Target:  

Drug Derivative

Research Areas:  

Cardiovascular Disease

AF 698 is a phthalate derivative of Apovincamine (HY-135743) that can be used as a peripheral vasodilator with selective vasomotor effects on cerebral microvascular circulation. AF 698 has better vasodilator effect than Vincamine (HY-B1021), but there is no significant difference in the protective effect of the two drugs against hypobaric hypoxia-induced lethality in mice .
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